7 completed, 2 recruiting, 1 active not recruiting, 1 terminated. 11 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 7, Recruiting 2, Active not recruiting 1, Terminated 1 |
| Phase 2 | 3 | Active not recruiting 1, Completed 1, Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Valganciclovir vs. Letermovir for CMV Prophylaxis in Heart Transplant Letermovir, Valganciclovir - CMV Viremia, Heart Transplant Infection | Phase 2 / Phase 3 | Recruiting | Columbia University | 150 | 2025-09-12 | 2026-10-02 |
| BiodEgradable Soaked Amiodarone paTch Use for the Prevention of Atrial Fibrillation After Cardiac Surgery topical amiodarone, saline solution patch - Atrial Fibrillation (AF) | Phase 3 | Recruiting | Jilin Heart Hospital | 500 | 2025-02-15 | 2025-12-09 |
| Extended-release Buprenorphine Compared to Sublingual Buprenorphine in Rural Settings (RXR) Injectable extended-release buprenorphine, Sublingual buprenorphine-naloxone - Opioid-Related Disorders, Substance-Related Disorders | Phase 3 | Completed | Yih-Ing Hser | 140 | 2024-10-14 | 2026-04-29 |
| Effect of 'Cramp Bites' on Period Cramps in Women Aged 18-25 Cramp Bites by Aunt Flo's Kitchen - Dysmenorrhea Primary, Dysmenorrhea | Phase 2 / Phase 3 | Completed | Cornell University | 12 | 2022-07-21 | 2024-04-12 |
| Metformin in Alzheimer's Dementia Prevention Placebo oral tablet, extended release metformin - Mild Cognitive Impairment | Phase 2 / Phase 3 | Active not recruiting | Columbia University | 326 | 2021-03-22 | 2026-08-11 |
| Topical Vancomycin for Neurosurgery Wound Prophylaxis Vancomycin - Infection, Surgery | Phase 3 | Completed | Columbia University | 1103 | 2014-10-01 | 2025-10-29 |
| eMOMS of Rochester electronic intervention during pregnancy and postpartum, electronic intervention during pregnancy, Control - Gestational Weight Gain, Postpartum Weight Retention | Phase 3 | Completed | University of Rochester | 1641 | 2011-05-01 | 2015-12-02 |
| Safety and Tolerability of the Ketogenic Diet in Amyotrophic Lateral Sclerosis (ALS) KetoCal - Amyotrophic Lateral Sclerosis | Phase 3 | Terminated | Johns Hopkins University | 1 | 2009-11-01 | 2015-04-01 |
| Complementary and Alternative Medicine for Urological Symptoms(CAMUS) Saw Palmetto - first 24 weeks, Placebo - first 24 weeks, Saw Palmetto - weeks 24 - 48 - Urological | Phase 3 | Completed | University of Alabama at Birmingham | 369 | 2008-02-01 | 2012-10-12 |
| Treatment and Prevention of Severe Anemia in Pregnant Zanzibari Women multivitamin, mebendazole - Anemia, Low Birth Weight | Phase 3 | Completed | Cornell University | 2500 | 2004-04-01 | 2026-02-13 |
| Supplemental Selenium and Vitamin E and Pulmonary Function Vitamin E, Selenium, Vitamin E placebo - Chronic Obstructive Pulmonary Disease, Lung Diseases | Phase 3 | Completed | Cornell University | 2920 | 2003-08-01 | 2017-12-12 |
Amyotrophic Lateral Sclerosis (1) · Anemia (1) · Atrial Fibrillation (1) · Bacterial Infections (1) · Behavior (1) · Birth Weight (1) · Central Nervous System Infections (1) · Cognitive Dysfunction (1) · Dysmenorrhea (1) · Gestational Weight Gain (1) · Hyperplasia (1) · Infections (1) · Lung Diseases (1) · Lung Diseases, Obstructive (1) · Menstruation Disturbances (1)
Amiodarone (1) · Buprenorphine (1) · Control Groups (1) · Geritol (1) · Injections (1) · Mebendazole (1) · Metformin (1) · Postpartum Period (1) · Pregnancy (1) · Selenium (1) · Valganciclovir (1) · Vancomycin (1) · Vitamin E (1) · letermovir (1)
United States (8) · Canada (1) · China (1) · Tanzania (1)
Alan Cantor, PhD (1) · Christine M Olson, PhD (1) · E. Sander Connolly, M.D. (1) · Isabel D Fernandez, MD, MPH, PhD (1) · James M Tielsch, PhD (1) · Larissa Mooney, MD (1) · Massimo G Lemma, PhD (1) · Michael Barry, MD (1) · Patricia A. Cassano, PhD (1) · Rebecca J Stoltzfus, PhD (1) · Yih-Ing Hser, PhD (1)
PMID 21497839, PMID 21741692, PMID 21954478, PMID 23083656, PMID 25143156, PMID 25889509, PMID 25957183, PMID 27012420, PMID 27519183, PMID 28069560, PMID 28573669, PMID 29743026, PMID 30554184, PMID 34088249, PMID 37203336, PMID 41850520
R01AG062624 (1), R01HL071022 (1), U01DK063788 (1), UG1DA049435 (1)