45 completed, 18 terminated, 13 unknown, 9 recruiting. 95 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 95 | Completed 45, Terminated 18, Unknown 13, Recruiting 9, Not yet recruiting 5, Withdrawn 3, Enrolling by invitation 2 |
Follow Vancomycin: new trials by email Literature Review of Vancomycin trials Research Report on Vancomycin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Use of Fidaxomicin Compared to Vancomycin for Decolonization of C. Difficile in Patients With Inflammatory Bowel Disease Vancomycin (POC), Fidaxomicin - Inflammatory Bowel Disease (IBD), Clostridioides Difficile Infection | Phase 4 | Not yet recruiting | Brigham and Women's Hospital | 60 | 2026-09-01 | 2025-11-03 |
| Early Discontinuation of Antibiotics in Paediatric High-risk Febrile Neutropenia Early Discontinuation of Antibiotics, Standard Antibiotic Continuation Strategy - Febrile Neutropenia (FN), Pediatric Cancer | Phase 4 | Not yet recruiting | Hospital Universitari Vall d'Hebron Research Institute | 136 | 2026-06-01 | 2026-05-15 |
| Efficacy and Cost-Effectiveness of Topical Vancomycin Powder in Preventing Pediatric Ventriculoperitoneal Shunt Infections Across Different Etiologies Topical Vancomycin Powder, Standard Perioperative Care - Hydrocephalus, Ventriculoperitoneal Shunt Infection | Phase 4 | Not yet recruiting | Assiut University | 164 | 2026-05-01 | 2026-04-23 |
| Prevention of Infections in Cardiac Surgery (PICS): a Cluster-randomized Factorial Cross-over Trial Cefazolin, Vancomycin - Infection, Surgical Site | Phase 4 | Not yet recruiting | Hamilton Health Sciences Corporation | 38000 | 2026-03-01 | 2026-03-12 |
| A Pragmatic Clinical Trial Comparing the Risk of Acute Kidney Injury During Treatment With Vancomycin and Piperacillin-Tazobactam vs. Vancomycin and Cefepime in Hospitalized Patients Vancomycin, Piperacillin-tazobactam, Cefepime - Acute Kidney Injury | Phase 4 | Recruiting | University of Pennsylvania | 750 | 2026-01-28 | 2026-02-13 |
| A Study of Antibiotic Delivery to Prevent Infection After Breast Tissue Expander Placement Tissue Expander (TE), Vancomycin and Gentamicin, Stimulan Rapid Cure - Breast Cancer | Phase 4 | Recruiting | Memorial Sloan Kettering Cancer Center | 392 | 2025-10-21 | 2026-07-10 |
| Does Staphylococcus Aureus Bacteremia Early Dual Therapy Improve Outcomes? Early Dual IV Antibiotic Therapy - MRSA, Early Dual IV Antibiotic Therapy - MSSA, Single Agent IV Antibiotic Therapy - MRSA - Staphylococcus Aureus Bacteremia | Phase 4 | Enrolling by invitation | West Virginia University | 300 | 2025-09-15 | 2026-09-17 |
| Daptomycin vs. Vancomycin for the Treatment of Methicillin Resistant S. Aureus Bacteremia Daptomycin for Injection, Vancomycin (IV) - Staphylococcus Aureus Septicemia, Staphylococcus Aureus Bacteremia | Phase 4 | Recruiting | Todd C. Lee MD MPH FIDSA | 300 | 2024-11-14 | 2026-09-09 |
| Linezolid or Vancomycin Surgical Site Infection Prophylaxis Vancomycin Injection, Linezolid Injection - Antibiotic Prophylaxis, General Surgery | Phase 4 | Recruiting | Assistance Publique Hopitaux De Marseille | 1160 | 2024-11-12 | 2026-02-05 |
| Powdered Intrawound Vancomycin in Open Fractures Trial Vancomycin 1000 MG - Open Fracture, Trauma | Phase 4 | Not yet recruiting | University of Manitoba | 350 | 2024-11-01 | 2024-09-19 |
| Prophylactic Antibiotics for Surgical Site Infections and Beta-Lactam Allergy cephalosporin, Second tier antibiotic (Vancomycin) - Surgical Site Infection, Beta-lactam Allergy | Phase 4 | Withdrawn | University of Texas Southwestern Medical Center | 2024-08-16 | 2023-12-15 | |
| Vancomycin in TKAs Vancomycin - Total Knee Arthroplasty | Phase 4 | Recruiting | University of California, San Diego | 30 | 2024-06-10 | 2026-06-03 |
| Antibiotics and Vaccine Immune Responses Study BCG vaccine, Yellow Fever vaccine, Vancomycin Oral Capsule - Vaccine Response Impaired | Phase 4 | Recruiting | South Australian Health and Medical Research Institute | 348 | 2023-11-23 | 2026-09-17 |
| Comparing Oral Versus Parenteral Antimicrobial Therapy Amoxicillin, amoxicillin-clavulanate, cefadroxil, cefpodoxime, cefalexin, ciprofloxacin, delafloxacin, doxycycline, levofloxacin, linezolid, Ampicillin, ampicillin-sulbactam, cefazolin, cefepime, ceftaroline, ceftazidime, ceftazidime-avibactam, dalbavancin, daptomycin, ertapenem - Endovascular Infection, Bone and Joint Infection | Phase 4 | Terminated | West Virginia University | 94 | 2023-08-04 | 2025-08-26 |
| Continuous vs. Intermittent Infusion Vancomycin Vancomycin Continuous Infusion, Vancomycin Intermittent Infusion - Vancomycin | Phase 4 | Completed | Aaron Cook | 37 | 2023-05-22 | 2025-12-15 |
| Efficacy of Diluted Betadine vs Antibiotic Installation Before Surgical Wound Closure in Prevention of Post Cardiac Surgery Wound Infection Betadine, Vancomycin - Surgical Wound Infection | Phase 4 | Unknown | Assiut University | 80 | 2022-09-01 | 2022-03-11 |
| The Effect of Intrawound Vancomycin Powder in Spine Surgery Vancomycin - Spine Disease | Phase 4 | Recruiting | Windsor-Essex Compassionate Care Community | 1643 | 2022-03-27 | 2024-04-23 |
| Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL) Amoxycillin, Cefalexin, Dicloxacillin, Linezolid, Levofloxacin, Rifampicin, Ampicillin, Oxacillin, Vancomycin, Daptomycin, Ceftriaxone, Cefepime, Ceftaroline - Endocarditis | Phase 4 | Terminated | West Virginia University | 5 | 2022-03-16 | 2026-05-05 |
| Staphylococcus Aureus Network Adaptive Platform Trial Cefazolin, Penicillin, Clindamycin - Staphylococcus Aureus Bacteremia | Phase 4 | Recruiting | University of Melbourne | 8000 | 2022-02-16 | 2026-05-06 |
| Bezlotoxumab Versus FMT for Multiple Recurrent CDI Bezlotoxumab, Fecal Microbiota Transplantation (FMT), Vancomycin oral - Clostridium Infections, Clostridioides Difficile | Phase 4 | Withdrawn | Leiden University Medical Center | 2022-01-01 | 2023-03-28 |
Showing 20 of 95. Sign in to see all of them.
Infections (12) · Clostridium Infections (11) · Surgical Wound Infection (11) · Staphylococcal Infections (5) · Endocarditis (4) · Febrile Neutropenia (4) · Fractures, Open (4) · Bacteremia (3) · Cellulitis (3) · Diarrhea (3) · Neoplasms (3) · Pneumonia (3) · Pneumonia, Ventilator-Associated (3) · Acute Kidney Injury (2) · Arrhythmias, Cardiac (2)
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (4) · Pfizer (3) · Population Health Research Institute (3) · West Virginia University (3) · Assiut University (2) · Astellas Pharma Europe Ltd. (2) · Forest Laboratories (2) · University Hospital, Ghent (2) · University of California, San Diego (2) · University of Cincinnati (2) · University of Colorado, Denver (2) · Washington University School of Medicine (2) · Aaron Cook (1) · Assistance Publique Hopitaux De Marseille (1) · Baylor College of Medicine (1)
United States (55) · Canada (9) · Spain (7) · Belgium (6) · France (5) · Australia (4) · Germany (4) · Poland (4) · Puerto Rico (4) · Russia (4) · United Kingdom (4) · Argentina (3) · Austria (3) · Brazil (3) · Greece (3)
Donald Poretz, MD (2) · Pieter De Cock, Prof (2) · A. Krishna Rao, MD, MS (1) · Aaron M Cook, PharmD (1) · Aki Havulinna, MD, PhD (1) · Alan G Smulian, M.B.B.Ch. (1) · Andrew Krahn, MD (1) · Andrew Maternowski, MD (1) · Anne Smits, MD (1) · Arif R Sawari, MD, MSc, MBA (1) · Arif R. Sarwari, MD, MSc, MBA (1) · Brandon Oto (1)
PMID 24011955, PMID 15327406, PMID 15509186, PMID 18719064, PMID 19222623, PMID 19376733, PMID 20350927, PMID 20458318, PMID 21412147, PMID 22083832, PMID 22770644, PMID 24279701, PMID 25048851, PMID 26196695, PMID 26529126, PMID 26547411, PMID 26592763, PMID 27600290, PMID 28101605, PMID 29273269, PMID 29608680, PMID 29937192, PMID 30355158, PMID 30858203, PMID 30911926, PMID 30915685, PMID 30995208, PMID 31833540, PMID 32011685, PMID 32029130, PMID 32222460, PMID 32859235, PMID 33413809, PMID 33441409, PMID 33560404, PMID 34017999, PMID 34303860, PMID 35833959, PMID 37797310, PMID 37837651, PMID 39934879, PMID 40260835, PMID 41159585, PMID 41419216, PMID 41433510, PMID 41974145, PMID 42102324, PMID 42308484, PMID 42309115
2025 (1), R21AI176298 (1)