505 completed, 194 unknown, 176 recruiting, 62 terminated. 1087 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1087 | Completed 505, Unknown 194, Recruiting 176, Terminated 62, Not yet recruiting 53, Active not recruiting 43, Withdrawn 32, Enrolling by invitation 14, Suspended 8 |
Follow Transcranial Direct Current Stimulation: new trials by email Literature Review of Transcranial Direct Current Stimulation trials Research Report on Transcranial Direct Current Stimulation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multiparameter Optimized tES for Memory in Aging Transcranial electrical stimulation - Healthy Aging | Not applicable | Withdrawn | Medical University of South Carolina | 2026-12-31 | 2026-02-25 | |
| Improving Awareness for Spatial Neglect With tDCS transcranial direct current stimulation (tDCS) - Stroke, Anosognosia | Not applicable | Not yet recruiting | University of Geneva, Switzerland | 12 | 2026-12-01 | 2025-05-30 |
| Cognitive Enhancement in Recurrent Depression (The COG-D-R Study) Depression Cognitive Training, Non-Specific Cognitive Training, tDCS (active stimulation) - Aging, Depression | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 69 | 2026-12-01 | 2026-10-21 |
| Influence of Transcranial Electrical Stimulation on Arm and Hand Function After Cervical Spinal Cord Injury transcranial direct current stimulation (tDCS) + FTP, transcranial pulsed current stimulation (tPCS) + FTP, transcranial random noise stimulation (tRNS) + FTP - Spinal Cord Injury | Not applicable | Not yet recruiting | Shepherd Center, Atlanta GA | 12 | 2026-12-01 | 2026-11-05 |
| Network-based tDCS for Apathy transcranial direct current stimulation, sham stimulation - Apathy, Brain Stimulation | Not applicable | Not yet recruiting | Hebrew SeniorLife | 20 | 2026-11-10 | 2026-10-28 |
| A Novel Multimodal Approach to Promote Motor Recovery and Plasticity After Stroke tRNS (Transcranial Random Noise Stimulation), FES (Functional Electrical Stimulation)-assisted task-specific practice, Sham-tRNS (Transcranial Random Noise Stimulation) - Stroke | Not applicable | Not yet recruiting | University of Utah | 78 | 2026-11-02 | 2026-10-22 |
| Transcranial Electrical Stimulation for Comorbid Depression and Chronic Pain tDCS, alpha-tACS, Sham - Depression Disorder, Chronic Pain | Not applicable | Recruiting | Shanghai Mental Health Center | 160 | 2026-11-01 | 2026-09-04 |
| Effects of Anodal Transcranial Direct Current Stimulation on Muscle Inhibition After ACL Reconstruction Anodal Transcranial Direct Current Stimulation (tDCS), Standard Physical Therapy - ACL Reconstruction | Not applicable | Not yet recruiting | University of Lahore | 64 | 2026-11-01 | 2026-10-09 |
| Combined Functional Electrical and Transcranial Direct Current Stimulation for Foot Drop Standard protocol for combo of FES and tDCS - Falls, Foot Drop | Not applicable | Recruiting | Saint Joseph's University, Philadelphia | 30 | 2026-11-01 | 2026-10-22 |
| Lily's Grace Temporal Interference TES-TI, Sham Stimulation, Structural and Functional MRI - Epilepsy | Not applicable | Not yet recruiting | University of Wisconsin, Madison | 24 | 2026-11-01 | 2026-10-30 |
| Transcranial Direct Current Stimulation for Chemotherapy-Related Chronic Pain in Cancer Survivors Active tDCS with Sternberg task, Sham tDCS with Sternberg task - Chronic Pain, Neuropathic Pain | Not applicable | Not yet recruiting | Instituto de investigación e innovación biomédica de Cádiz | 60 | 2026-11-01 | 2026-11-03 |
| Cerebellar Brain Stimulation Plus Language Therapy for People at Risk of Poor Aphasia Recovery After Stroke Cathodal cerebellar transcranial direct current stimulation, Computerized language therapy - Aphasia, Stroke | Not applicable | Not yet recruiting | Johns Hopkins University | 8 | 2026-11-01 | 2026-11-03 |
| Dynamic Stabilometry Combined With Transcranial Direct Current Stimulation for Balance and Motor Recovery After Ischemic Stroke Dynamic Stabilometry With Biofeedback, Static Stabilometry, Anodal tDCS - Hemiparesis, Ischemic Stroke | Not applicable | Not yet recruiting | Samara State Medical University | 120 | 2026-10-28 | 2026-11-03 |
| tACS for Working Memory in Schizophrenia transcranial alternating current stimulation, sham stimulation - Schizophrenia, Working Memory | Not applicable | Recruiting | Central South University | 30 | 2026-10-26 | 2026-10-28 |
| Comparative Effects of tDCS and tACS on Pain, Dexterity, and Strength in Diabetic Peripheral Neuropathy Transcranial Direct Current Stimulation (tDCS), Transcranial Alternating Current Stimulation (tACS) - Diabetic Peripheral Neuropathy (DPN) | Not applicable | Active not recruiting | University of Management and Technology Lahore | 46 | 2026-10-22 | 2026-11-03 |
| Mechanistic Validation of Human Multipolar TES-TI: Amplitude Modulation, Frequency, and Benchmarking TES-TI with hdEEG - Transcranial Electric Stimulation | Not applicable | Recruiting | University of Wisconsin, Madison | 24 | 2026-10-09 | 2026-10-23 |
| Effects of Non-invasive Brain Stimulation on Pain Avoidance Behavior in Chronic Pain Patients transcranial alternating current stimulation (tACS) - Complex Regional Pain Syndrome (CRPS) | Not applicable | Recruiting | The Cleveland Clinic | 30 | 2026-10-01 | 2026-08-28 |
| Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls TES-TI, Sham TES-TI - Schizophrenia | Not applicable | Recruiting | University of Wisconsin, Madison | 20 | 2026-10-01 | 2026-10-01 |
| Effects of Transcranial Direct Current Stimulation on Cyberaggressive Behaviour in Adults Anodal transcranial direct current stimulation, Cathodal transcranial direct current stimulation, Sham transcranial direct current stimulation - Cyberaggression | Not applicable | Not yet recruiting | Nanyang Technological University | 159 | 2026-10-01 | 2026-11-02 |
| Noninvasive Brain Stimulation Combined With Written Exposure Therapy for PTSD in Military Personnel With TBI Transcranial Direct Current Stimulator, Written Exposure Therapy - Post Traumatic Stress Disorder | Not applicable | Not yet recruiting | The University of Texas Health Science Center at San Antonio | 150 | 2026-09-30 | 2026-07-20 |
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Stroke (161) · Cognitive Dysfunction (63) · Schizophrenia (55) · Depression (52) · Chronic Pain (43) · Alzheimer Disease (40) · Depressive Disorder, Major (39) · Parkinson Disease (38) · Aphasia (26) · Anxiety Disorders (23) · Ischemic Stroke (22) · Brain Injuries, Traumatic (21) · Multiple Sclerosis (21) · Psychotic Disorders (21) · Pain (20)
Charite University, Berlin, Germany (22) · University of Minnesota (22) · Spaulding Rehabilitation Hospital (18) · Mahidol University (16) · Riphah International University (16) · Federal University of Paraíba (14) · Johns Hopkins University (14) · University of Liege (13) · Hebrew SeniorLife (12) · Hospital de Clinicas de Porto Alegre (12) · Medical University of South Carolina (12) · The Hong Kong Polytechnic University (12) · Seoul National University Hospital (11) · Xuanwu Hospital, Beijing (11) · The University of Texas at Dallas (10)
United States (353) · China (69) · Brazil (66) · Germany (61) · France (49) · Canada (42) · Italy (41) · Belgium (34) · Spain (34) · United Kingdom (34) · South Korea (23) · Taiwan (19) · Pakistan (18) · Turkey (Türkiye) (17) · Hong Kong (16)
Mirza Obaid Baig, MSPT (10) · Wanalee Klomjai, PhD (8) · Suellen Andrade (7) · Felipe Fregni, MD, PhD, MPH (6) · Wolnei Caumo, PhD (5) · Brad Manor, PhD (4) · Felipe Fregni, MD PhD MPH (4) · Flavio Frohlich, PhD (4) · Joan Camprodon, MD, PhD, MPH (4) · Stephen Bornheim, Msc (4) · Wen Li, PhD (4) · Yvonne Han, PhD (4) · Alvaro Pascual-Leone, Dr. (3)
PMID 33175411, PMID 28709880, PMID 10990547, PMID 17452283, PMID 16427357, PMID 19348793, PMID 20633386, PMID 21320389, PMID 22031888, PMID 27866120, PMID 28440034, PMID 34196963, PMID 15753425, PMID 17086200, PMID 19064743, PMID 19109497, PMID 19833552, PMID 20395612, PMID 21631313, PMID 22037126, PMID 22581236, PMID 22695026, PMID 23370085, PMID 24345389, PMID 24574549, PMID 26848997, PMID 26890096, PMID 27056623, PMID 28566193, PMID 29550525, PMID 30083095, PMID 30902640, PMID 31617873, PMID 31672712, PMID 32147282, PMID 33045706, PMID 34062145, PMID 34785366, PMID 34930421, PMID 37689323, PMID 10234222, PMID 10348007, PMID 10385840, PMID 10560028, PMID 10576727, PMID 10781919, PMID 10796360, PMID 10881154, PMID 11150345, PMID 11240089
1RF1MH116987-01 (2), 2017 (2), K23MH111977 (2), P2CHD086844 (2), R01MH132209 (2), 1IK2RX002420-01A2 (1), 1UG3DA048508-01 (1), 1UG3DA061594 (1), 2015 (1), 2016 (1), 2018 (1), 2023 (1), 5KL2TR001429 (1), F31DC020352 (1), I01RX000180 (1)