3 completed, 3 recruiting, 1 terminated, 1 withdrawn. 8 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 3, Recruiting 3, Terminated 1, Withdrawn 1 |
| Phase 2 | 1 | Completed 1 |
Follow sodium thiosulfate: new trials by email Literature Review of sodium thiosulfate trials Research Report on sodium thiosulfate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss Audiometric Test, Auditory Brainstem Response, Biospecimen Collection - Childhood Medulloblastoma | Phase 3 | Recruiting | Children's Oncology Group | 225 | 2023-02-20 | 2026-08-25 |
| Better Evidence and Translation for Calciphylaxis Vitamin K1, Magnesium citrate, Sodium Thiosulfate - Calciphylaxis | Phase 3 | Recruiting | University of Sydney | 350 | 2021-08-26 | 2025-08-13 |
| A Multi-institutional Study for Treatment of Children With Newly Diagnosed Hepatoblastoma Using a Modified PHITT Strategy Sodium Thiosulfate Injection, Primary surgery resection, mono CDDP-Group A2 - Hepatoblastoma | Phase 3 | Recruiting | Shanghai Children's Medical Center | 330 | 2021-03-01 | 2026-05-04 |
| Sodium Thiosulfate for Treatment of Calcinosis Associated With Juvenile and Adult Dermatomyositis Sodium Thiosulfate - Dermatomyositis, Idiopathic Inflammatory Myopathies | Phase 2 / Phase 3 | Completed | National Institute of Environmental Health Sciences (NIEHS) | 15 | 2017-10-05 | 2024-11-26 |
| A Phase 3 Clinical Trial of Intravenous Sodium Thiosulfate in Acute Calciphylaxis Patients Sodium Thiosulfate, Placebo-Normal Saline - Calciphylaxis | Phase 3 | Terminated | Hope Pharmaceuticals | 29 | 2017-05-24 | 2020-05-19 |
| Double-blind Trial of Sodium Thiosulfate for the Treatment of Pain Associated With Calcific Uremic Arteriolopathy Sodium thiosulfate, Placebo - Calciphylaxis, Calcific Uremic Arteriolopathy | Phase 3 | Withdrawn | American Regent, Inc. | 2015-01-30 | 2025-05-07 | |
| Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy sodium thiosulfate, examination - Brain Tumor, Central Nervous System Tumor | Phase 3 | Completed | Children's Oncology Group | 131 | 2008-06-23 | 2023-11-09 |
| Cisplatin With or Without Sodium Thiosulfate in Treating Young Patients With Stage I, II, or III Childhood Liver Cancer cisplatin, sodium thiosulfate - Liver Cancer, Ototoxicity | Phase 3 | Completed | University of Birmingham | 116 | 2007-12-15 | 2018-05-29 |
Calciphylaxis (3) · Hepatoblastoma (3) · Calcinosis (2) · Liver Neoplasms (2) · Medulloblastoma (2) · Ototoxicity (2) · Brain Neoplasms (1) · Calcium Metabolism Disorders (1) · Central Nervous System Neoplasms (1) · Dermatomyositis (1) · Metabolic Diseases (1) · Myositis (1) · Neuroblastoma (1) · Osteosarcoma (1) · Ovarian Germ Cell Cancer (1)
Children's Oncology Group (2) · American Regent, Inc. (1) · Hope Pharmaceuticals (1) · National Institute of Environmental Health Sciences (NIEHS) (1) · Shanghai Children's Medical Center (1) · University of Birmingham (1) · University of Sydney (1)
United States (5) · Canada (3) · Australia (2) · United Kingdom (2) · China (1) · New Zealand (1)
Adam I Schiffenbauer, M.D. (1) · Craig Sherman, MD (1) · David R. Freyer, DO, MS (1) · Linda Mundy, MD, PhD (1) · Meg Jardine (1) · Milind D. Ronghe, MD (1) · Ralph Salloum (1) · Yi-Jin Gao, MD (1)
PMID 27914822, PMID 29924955, PMID 22547603, PMID 23831416, PMID 27884679, PMID 31160205, PMID 39186385
U10CA180886 (1)