17 completed, 5 unknown, 1 recruiting, 1 terminated. 24 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 24 | Completed 17, Unknown 5, Recruiting 1, Terminated 1 |
Follow Saline Solution, Hypertonic: new trials by email Literature Review of Saline Solution, Hypertonic trials Research Report on Saline Solution, Hypertonic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SGLT-2 Inhibitor and High-Dose Furosemide Plus Small-Volume Hypertonic Saline Solution in Acute HF Dapagliflozin tablet, Hypertonic Saline Solution, 1 Ml, Furosemide Injection - Heart Failure Acute, Diabetes Type 2 | Phase 4 | Unknown | University of Palermo | 544 | 2024-06-01 | 2024-06-06 |
| Hypertonic Saline for MAC Hypertonic saline, Azithromycin, Ethambutol - Nontuberculous Mycobacterial Lung Disease, Nontuberculous Mycobacterium Infection | Phase 4 | Recruiting | Oregon Health and Science University | 50 | 2021-05-18 | 2026-10-20 |
| Trial on The Efficacy of Hypertonic Saline on Non-CF CSLD. Nebulized 5% Hypertonic saline - Bronchiectasis | Phase 4 | Completed | University of Malaya | 46 | 2021-02-04 | 2023-12-01 |
| Hypertonic Saline Inhalation in Acute Bronchiolitis normal saline and salbutamol, hypertonic saline and salbutamol, Hypertonic saline - Acute Bronchiolitis | Phase 4 | Unknown | Assiut University | 75 | 2020-07-20 | 2020-02-11 |
| Type and Frequency of Nasal Irrigation in Rhinosinusitis Patients Isotonic Saline ( 0.9% Sodium Chloride Saline), Hypertonic Saline ( 3% Sodium Chloride Saline) - Otorhinolaryngologic Diseases, Rhinosinusitis | Phase 4 | Unknown | Imam Abdulrahman Bin Faisal University | 100 | 2020-02-01 | 2020-01-22 |
| Randomized, Controlled Trial of Hyperosmotlar Saline for Rotator Cuff Repair Irrigation Solution Hypertonic saline - Arthroscopic Shoulder Surgery, Rotator Cuff Tear | Phase 4 | Unknown | Rothman Institute Orthopaedics | 100 | 2019-01-01 | 2018-11-13 |
| Hypertonic Saline for Fluid Resuscitation After Cardiac Surgery Hypertonic saline, 0.9% saline - Cardiovascular Diseases, Valvular Heart Disease | Phase 4 | Completed | Insel Gruppe AG, University Hospital Bern | 165 | 2018-02-27 | 2020-03-24 |
| The Hemodynamic Effects of Hypertonic Saline Preload Versus Coload Measured by Non-invasive Cardiometry in Patients Undergoing TURP Surgery hypertonic saline 3% - Transurethral Resection of Prostate Syndrome | Phase 4 | Completed | Nazmy Edward Seif | 100 | 2017-11-01 | 2025-02-12 |
| Efficacy and Safety of Rapid Intermittent Compared With Slow Continuous Correction in Severe Hyponatremia Patients 3% hypertonic saline - Hyponatremia Symptomatic | Phase 4 | Completed | Seoul National University Hospital | 178 | 2016-08-01 | 2020-04-09 |
| Hypertonic Saline Resuscitation in Trauma Patients After Hemorrhage Control Sodium Chloride [3%], Sodium Chloride [0.9%] - Abdominal Injuries | Phase 4 | Terminated | Fundacion Clinica Valle del Lili | 52 | 2015-11-27 | 2020-06-11 |
| Effects of Hypertonic Saline Solution (NACL 3%+NAHCO3) on Nasal Inflammation in Children With AR. RinASol- Pilot Study hypertonic saline solution (NACL 3%+NAHCO3), Saline Solution (NACL 0,9%) - Allergic Rhinitis | Phase 4 | Completed | Stefania La Grutta, MD | 30 | 2015-10-01 | 2017-01-12 |
| Efficacy and Safety of 3% Hypertonic Saline Inhalation (24h vs 72h) to Treat Acute Bronchiolitis in Hospitalized Infants 3 % hypertonic saline up to 72H, 3 % hypertonic saline up to 24H - Bronchiolitis | Phase 4 | Completed | University Hospital, Grenoble | 120 | 2014-11-01 | 2017-11-06 |
| Nebulized Hypertonic Saline for Inpatient Use in COPD hypertonic saline, standard saline - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | OhioHealth | 70 | 2014-10-01 | 2017-11-22 |
| Epinephrine, Dexamethasone, and Hypertonic Saline in Bronchiolitis, Randomised Clinical Trial of Efficacy and Safety Epinephrine and Dexamethasone, Hypertonic Saline, Normal Saline - Bronchiolitis | Phase 4 | Completed | Hospital General Naval de Alta Especialidad - Escuela Medico Naval | 120 | 2013-01-01 | 2015-07-08 |
| Comparison of 20% Mannitol and 3% Hypertonic Saline for Cerebral Relaxation During Elective Supratentorial Craniotomies 20% mannitol bolus administration, Hypertonic saline 3% bolus administration - Osmotherapy, Intracranial Pressure | Phase 4 | Unknown | Université de Sherbrooke | 80 | 2012-09-01 | 2012-12-07 |
| Efficacy of Nebulised Hypertonic Saline (3%) Among Children With Bronchiolitis. L-Epinephrine and Normal Saline (0.9%), L-Epinephrine and Hypertonic Saline (3%) - Bronchiolitis | Phase 4 | Completed | Dr. Aayush Khanal, MD | 100 | 2011-01-01 | 2013-05-31 |
| 7% Hypertonic Saline for Acute Bronchiolitis Hypertonic saline and epinephrine, Normal saline and epinephrine - Acute Bronchiolitis | Phase 4 | Completed | Le Bonheur Children's Hospital | 101 | 2010-11-01 | 2013-06-11 |
| Hypertonic Saline for Acute Bronchiolitis Nebulized 3% saline, Nebulized 0.9% Normal Saline - Bronchiolitis, Viral, Saline Solution, Hypertonic | Phase 4 | Completed | Children's Hospital of Philadelphia | 62 | 2010-10-01 | 2014-08-19 |
| Study of Long-term Treatment With Hypertonic Saline in Patients With Cystic Fibrosis Hypertonic saline - Cystic Fibrosis | Phase 4 | Completed | Adelaida Lamas Ferreiro | 71 | 2009-03-01 | 2013-01-30 |
| Effectiveness of Nebulized Hypertonic Saline and Epinephrine in Hospitalized Infants With Bronchiolitis 3% hypertonic saline solution - Bronchiolitis | Phase 4 | Completed | Federico II University | 136 | 2008-11-01 | 2011-02-21 |
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Bronchiolitis (6) · Bronchiolitis, Viral (2) · Pulmonary Disease, Chronic Obstructive (2) · Abdominal Injuries (1) · Brain Injuries (1) · Brain Injuries, Traumatic (1) · Bronchiectasis (1) · Cardiovascular Diseases (1) · Chronic Cough (1) · Cystic Fibrosis (1) · Diabetes Mellitus, Type 2 (1) · Dyspnea (1) · Heart Valve Diseases (1) · Hyponatremia (1) · Inflammation (1)
University Hospital, Grenoble (2) · Adelaida Lamas Ferreiro (1) · Assiut University (1) · Children's Hospital of Philadelphia (1) · Dr. Aayush Khanal, MD (1) · Federal University of São Paulo (1) · Federico II University (1) · Fundacion Clinica Valle del Lili (1) · Hamad Medical Corporation (1) · Haukeland University Hospital (1) · Hospital General Naval de Alta Especialidad - Escuela Medico Naval (1) · Imam Abdulrahman Bin Faisal University (1) · Insel Gruppe AG, University Hospital Bern (1) · Le Bonheur Children's Hospital (1) · Nazmy Edward Seif (1)
United States (4) · Canada (2) · France (2) · Italy (2) · Colombia (1) · Egypt (1) · Malaysia (1) · Mexico (1) · Nepal (1) · Norway (1) · Qatar (1) · Saudi Arabia (1) · South Korea (1) · Spain (1) · Switzerland (1)
Aayush Khanal, MD (1) · Adelaida Lamas, MD (1) · Anna M Nathan (1) · Arun Sharma, MD (1) · Daniel Davis, MD (1) · Fakir C Gami, MD (1) · Giuseppe Miceli, PhD (1) · Jay Pershad, MD (1) · Jean-Francois Payen, MD, PhD (1) · Joerg C Schefold, MD (1) · Joseph Zorc, MD, MSCE (1) · Khalid M. Al-Ansari, FRCPC,FAAP (1)
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