10 completed, 5 unknown, 2 recruiting, 1 terminated. 9 Not applicable, 4 Phase 3, 3 Phase 4, 2 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 3, Recruiting 2, Unknown 2, Terminated 1, Withdrawn 1 |
| Phase 3 | 4 | Completed 4 |
| Phase 4 | 3 | Unknown 2, Completed 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 1 | Unknown 1 |
Follow Plasmalyte: new trials by email Literature Review of Plasmalyte trials Research Report on Plasmalyte
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Heart-Lung Machine: Impact of the Priming Solution on Acid-Base Balance, Electrolytes and Outcome on Patients Undergoing Cardiac Surgery Ringer's Acetate 80, Plasmalyte, Ringer's Acetate no add - Acid Base Imbalance, Osmolality Disturbance | Not applicable | Recruiting | Region Skane | 80 | 2025-09-01 | 2025-12-05 |
| To Study Effect of Injection Pentoxifylline on Liver Growth After Major Liver Surgery Pentoxifylline (also known as oxpentifylline), Plasmalyte - Liver Regeneration | Not applicable | Recruiting | Institute of Liver and Biliary Sciences, India | 60 | 2025-01-01 | 2025-07-25 |
| Evaluation of the Protective Efficacy of TV003 or Previous Zika Infection Against Infection With ZIKV-SJRP Challenge Compared to DENV and ZIKV-naïve Controls Against Infection With ZIKV-SJRP Challenge TetraVax-DV-TV003 (TV003), Plasmalyte, Challenge virus ZIKV-SJRP/2016-184 - Zika Virus | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 27 | 2024-09-24 | 2026-03-09 |
| Cartilage Recovery in Adults With Knee Osteorthritis by Mesenchymal Cell Therapy: Randomized Trial of Radiologic and Clinical Outcomes INMUNOCEM, PLACEBO COMPARATOR - Knee Osteoarthritis | Phase 2 | Unknown | GUSTAVO SALGUERO | 32 | 2023-10-01 | 2023-07-07 |
| Efficacy of 5% Albumin v/s Plasmalyte in Combination With 20% Albumin for Fluid Resuscitation in Cirrhosis With Sepsis Induced Hypotension 20% Albumin, 5% Albumin, Plasmalyte - Liver Cirrhosis | Not applicable | Unknown | Institute of Liver and Biliary Sciences, India | 120 | 2023-09-30 | 2023-10-10 |
| Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure Norepinephrine, Lactated Ringers, Intravenous, normal saline - Respiratory Failure, Hypotension and Shock | Phase 3 | Completed | Wright State University | 42 | 2022-08-09 | 2024-07-15 |
| Better Evidence for Selecting Transplant Fluids Plasma-Lyte 148 (approx. pH 7.4) IV Infusion, 0.9% SODIUM CHLORIDE 9g/L injection BP - End Stage Kidney Disease, Delayed Graft Function | Phase 3 | Completed | The University of Queensland | 808 | 2018-01-26 | 2024-10-15 |
| Influence of Albumin on Acute Renal Dysfunction Associated With Cardiac Surgery Under Extracorporeal Circulation Human albumin, Plasmalyte - Acute Kidney Injury | Phase 4 | Unknown | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 250 | 2018-01-10 | 2018-01-25 |
| Fluid Resuscitation in Burn Patients Plasmalyte, Ringer lactate - Severe Burns, Fluid Resuscitation | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 28 | 2017-08-09 | 2019-12-13 |
| A Low ChloridE hyperTonic Solution for Brain Edema Sodium chloride /sodium acetate (16.4%), Sodium chloride (23.4%), PlasmaLyte - Subarachnoid Hemorrhage, Acute Kidney Injury | Phase 1 | Completed | Emory University | 59 | 2017-06-28 | 2023-05-01 |
| Comparison of Colloid (20% Albumin) Versus Crystalloid (Plasmalyte) for Fluid Resuscitation in Cirrhotics With Sepsis Induced Hypotension. 20% Albumin, Plasmalyte - Cirrhosis With Sepsis | Not applicable | Completed | Institute of Liver and Biliary Sciences, India | 100 | 2016-12-01 | 2021-08-26 |
| Comparison of Ringer Lactate and Isotonic Acetate Solution as Perioperative Maintenance Fluid for Children Ringer Lactate, Plasmalyte - Hyponatremia | Not applicable | Unknown | Post Graduate Institute of Medical Education and Research, Chandigarh | 50 | 2016-09-01 | 2016-10-18 |
| Fresh Frozen Plasma and Plasmalyte ® for Priming Cardiopulmonary Bypass in Infants and Children Surgery with CPB, Fresh Frozen Plasma, Plasmalyte - Congenital Heart Disease | Not applicable | Completed | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 60 | 2015-10-01 | 2018-12-05 |
| Effects of Goal-directed Fluid Therapy on Post-operative Outcomes in Children Undergoing Scoliosis Repair Plasmalyte, Goal-directed fluid therapy (GDT) - Scoliosis, Acute Kidney Injury | Not applicable | Terminated | University of British Columbia | 14 | 2015-06-01 | 2017-10-26 |
| Crystalloids or Colloids for Goal-directed Fluid Therapy With Closed-loop Assistance in Major Surgery Plasmalyte, Volulyte - Surgery | Phase 4 | Completed | Brugmann University Hospital | 160 | 2015-02-24 | 2018-01-19 |
| Perioperative Fluid Therapy With Balanced Crystalloids Plasmalyte, Ringerfundin - Acid Base Imbalance | Phase 3 | Completed | University Hospital Olomouc | 112 | 2014-01-01 | 2017-05-09 |
| Comparison of Priming Constituents in Patients Undergoing CPB Assisted Cardiac Surgery: HES 130/0.4 or Albumin 5% prime crystalloid, Human Albumin, Voluven - Coronary Artery Disease, Aortic Valve Disease | Not applicable | Withdrawn | University of Saskatchewan | 2013-11-01 | 2019-05-03 | |
| The Aim of This Investigation is to Compare the Influence of 0.9% Saline and Plasmalyte Solution on Acid-base Balance and Electrolytes in Healthy Patients Undergoing Major Spine Surgeries. 0.9% normal saline, plasmalyte - Spinal Surgery | Not applicable | Completed | Yonsei University | 50 | 2012-03-01 | 2013-05-16 |
| Chloride High Level Of Resuscitation Infusion Chloride High Level Of Resuscitation Infusion Delivered Evaluation Lower chloride fluids (Hartmann's solution and Plasmalyte®) - Shock, Critical Illness | Phase 4 | Unknown | Austin Health | 7000 | 2009-02-01 | 2010-02-25 |
Acute Kidney Injury (3) · Acid-Base Imbalance (2) · Acidosis (2) · Critical Illness (2) · Shock (2) · Aortic Valve Disease (1) · Burns (1) · Coronary Artery Disease (1) · Delayed Graft Function (1) · Heart Defects, Congenital (1) · Hyponatremia (1) · Hypotension (1) · Kidney Failure, Chronic (1) · Liver Cirrhosis (1) · Osteoarthritis, Knee (1)
Institute of Liver and Biliary Sciences, India (3) · Assistance Publique - Hôpitaux de Paris (1) · Austin Health (1) · Brugmann University Hospital (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · Emory University (1) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1) · GUSTAVO SALGUERO (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · Region Skane (1) · The University of Queensland (1) · University Hospital Olomouc (1) · University of British Columbia (1) · University of Saskatchewan (1)
India (4) · United States (3) · Australia (2) · Belgium (2) · Canada (2) · France (1) · New Zealand (1) · South Korea (1) · Spain (1) · Sweden (1)
Alexandre Joosten, MD (1) · Anna Durbin, M.D. (1) · Brigitte Ickx, Md, Pr (1) · Dr Abhinav Verma, MD (1) · Jo-Anne E Marcocoux, M. Sc. (1) · Jo-Anne E Marcoux, M. Sc. (1) · Jordi Miralles, MD (1) · Matthew Koroscil, MD (1) · Matthieu Legrand, MD, PhD (1) · Michael Collins, MBChB,FRACP,PhD (1) · Mona Momeni, MD,PhD (1) · Neerja Bhardwaj, MD (1) · Nor'azim Mohd Yunos, MBBS (1) · Owen Samuels, MD (1)
PMID 16537374, PMID 21037437, PMID 21705897, PMID 22816029, PMID 23073953, PMID 24253140, PMID 25472864, PMID 26123384, PMID 30428930, PMID 32391156, PMID 32450917, PMID 35042554, PMID 35460725, PMID 37343576
2008 (1), 2025 (1)