5 completed, 3 recruiting, 2 terminated, 1 unknown. 11 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 11 | Completed 5, Recruiting 3, Terminated 2, Unknown 1 |
| Phase 2 | 2 | Recruiting 2 |
Follow Phenylephrine: new trials by email Literature Review of Phenylephrine trials Research Report on Phenylephrine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Complication Rates in Cataract Surgery Patients Treated With Combined Pre-operative NSAID, OMIDRIA, and Subconjunctival Triamcinolone Acetonide Compared With Peri-operative SOC Omidria, {0.3%-1% Intraocular Solution}, VIGAMOX {0.5% moxifloxacin hydrochloride}, Kenalog {0.4 ml, 10mg/ml, triamcinolone acetonide}, Ketorolac (0.5%) {Toradol}, moxifloxacin (0.5%) {VIGAMOX}, prednisolone acetate (1%) {Pred Forte} - Cataract | Phase 1 / Phase 2 | Recruiting | Inder Paul Singh, M.D. | 94 | 2024-07-10 | 2024-11-29 |
| Use of Phenylephrine for Assessment of Mitral Regurgitation Severity Mydfrin - Mitral Regurgitation | Phase 1 / Phase 2 | Recruiting | Montefiore Medical Center | 35 | 2020-12-01 | 2025-07-20 |
| The Effect of Local Antioxidant Therapy on Racial Differences in Vasoconstriction Control (Phenylephrine), Phenylephrine + Apocynin, Phenylephrine + Allopurinol - Cardiovascular Diseases, Cardiovascular Risk Factor | Phase 1 | Completed | The University of Texas at Arlington | 24 | 2018-10-01 | 2020-11-05 |
| To Investigate the Gastrointestinal Behaviour of Two Triple Combination Products in Healthy Male Volunteers Acetaminophen 650mg+Dextromethorphan 20mg+Phenylephrine 10mg, Acetaminophen 325mg+Dextromethorphan 10mg+Phenylephrine 5mg - Common Cold | Phase 1 | Completed | GlaxoSmithKline | 28 | 2018-03-01 | 2019-06-24 |
| A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems Albuterol Sulfate, Nicardipine Hydrochloride, Dobutamine Hydrochloride - Drug-Related Side Effects and Adverse Reactions, Cardiovascular System Disease | Phase 1 | Terminated | Cambridge University Hospitals NHS Foundation Trust | 18 | 2017-04-24 | 2021-03-22 |
| The Effect of Brimonidine on Intraocular Pressure When Dilating Routine Patients Alphagan, Phenylephrine, Tropicamide - Intraocular Pressure | Phase 1 | Completed | Wake Forest University Health Sciences | 5 | 2016-09-01 | 2018-08-09 |
| Cardiovascular Effects of Angiotensin (1-7) in Essential Hypertension Angiotensin (1-7), Trimethaphan, Phenylephrine - Hypertension, Hypertension, Essential | Phase 1 | Terminated | Vanderbilt University | 24 | 2015-01-01 | 2024-01-09 |
| Phenylephrine Tumescence for Hemostasis in Surgery for Burn Injury Phenylephrine - Blood Loss, Surgical | Phase 1 | Recruiting | University of Manitoba | 24 | 2014-12-01 | 2026-05-14 |
| Vasopressors for Cerebral Oxygenation dopamine, phenylephrine - Hypoxia, Hypotension | Phase 1 | Unknown | Samsung Medical Center | 50 | 2012-12-01 | 2013-12-11 |
| To Test Bioequivalence Between Two Formulations of Paracetamol/Phenylephrine Paracetamol 500 mg/Phenylephrine 5 mg tablets, Paracetamol 1000 mg/Phenylephrine 10 mg sachet - Respiratory Tract Infections | Phase 1 | Completed | McNeil AB | 40 | 2010-03-01 | 2012-07-10 |
| The Pathophysiology of Orthostatic Hypotension Standing or upright tilt, Microneurography, QSweat - Autonomic Nervous System Diseases, Orthostatic Hypotension | Phase 1 | Completed | Vanderbilt University Medical Center | 10 | 1996-12-01 | 2021-05-12 |
Cardiovascular Diseases (2) · Autonomic Nervous System Diseases (1) · Blood Loss, Surgical (1) · Burns (1) · Cataract (1) · Common Cold (1) · Dizziness (1) · Drug-Related Side Effects and Adverse Reactions (1) · Essential Hypertension (1) · Headache (1) · Hemorrhage (1) · Hypertension (1) · Hypotension (1) · Hypotension, Orthostatic (1) · Hypoxia (1)
Cambridge University Hospitals NHS Foundation Trust (1) · GlaxoSmithKline (1) · Inder Paul Singh, M.D. (1) · McNeil AB (1) · Montefiore Medical Center (1) · Samsung Medical Center (1) · The University of Texas at Arlington (1) · University of Manitoba (1) · Vanderbilt University (1) · Vanderbilt University Medical Center (1) · Wake Forest University Health Sciences (1)
United States (7) · Canada (1) · Ireland (1) · South Korea (1) · United Kingdom (1)
Elisabeth Kruse, PhD (1) · Emily M Garland, PhD (1) · Hyun Joo Ahn (1) · Italo Biaggioni, MD (1) · Joseph Cheriyan, MBCHB, MA, FRCP (1) · Keith Walter, MD (1) · Mario Garcia, MD (1) · Paul Singh, MD (1)
2009 (1)