15 completed, 4 recruiting, 1 not yet recruiting, 1 suspended. 22 Phase 2, 7 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 22 | Completed 15, Recruiting 4, Not yet recruiting 1, Suspended 1, Unknown 1 |
| Phase 3 | 7 | Completed 4, Not yet recruiting 1, Recruiting 1, Suspended 1 |
| Phase 1 | 2 | Recruiting 2 |
Follow Phenylephrine: new trials by email Literature Review of Phenylephrine trials Research Report on Phenylephrine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Study of DA-001 as a Treatment for Hair Shedding Reduction and Hair Re-Growth DA-001, Placebo, Phenylephrine - Telogen Effluvium, Female Pattern Hair Loss | Phase 2 / Phase 3 | Not yet recruiting | Applied Biology, Inc. | 1120 | 2026-05-01 | 2026-04-13 |
| Study of Complication Rates in Cataract Surgery Patients Treated With Combined Pre-operative NSAID, OMIDRIA, and Subconjunctival Triamcinolone Acetonide Compared With Peri-operative SOC Omidria, {0.3%-1% Intraocular Solution}, VIGAMOX {0.5% moxifloxacin hydrochloride}, Kenalog {0.4 ml, 10mg/ml, triamcinolone acetonide}, Ketorolac (0.5%) {Toradol}, moxifloxacin (0.5%) {VIGAMOX}, prednisolone acetate (1%) {Pred Forte} - Cataract | Phase 1 / Phase 2 | Recruiting | Inder Paul Singh, M.D. | 94 | 2024-07-10 | 2024-11-29 |
| Vasopressor Impact on Brain Circulation, Organ Blood Flow and Tissue Oxygenation During Anesthesia Noradrenalin, Phenylephrine - Hypotension | Phase 2 / Phase 3 | Recruiting | University of Aarhus | 32 | 2023-12-20 | 2026-03-19 |
| The Effect of CPC on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near Syncope CPC - Capsaicin, Phenylephrine, Caffeine, Tilt Table Test, Placebo - Syncope, Vasovagal | Phase 2 | Completed | University of Wisconsin, Madison | 143 | 2021-07-20 | 2024-07-17 |
| Use of Phenylephrine for Assessment of Mitral Regurgitation Severity Mydfrin - Mitral Regurgitation | Phase 1 / Phase 2 | Recruiting | Montefiore Medical Center | 35 | 2020-12-01 | 2025-07-20 |
| Methylene Blue as a Third-line Vasopressor in Septic Shock Methylene Blue, Phenylephrine - Septic Shock | Phase 2 | Unknown | Carilion Clinic | 250 | 2019-12-01 | 2022-07-26 |
| The Phenylephrine vs. Norepinephrine Infusion Undergoing Cesarean Section Norepinephrine, Phenylephrine, Ringer's Solution - Cesarean Section Complications | Phase 2 / Phase 3 | Completed | China International Neuroscience Institution | 238 | 2019-02-20 | 2020-02-10 |
| Norepinephrine or Phenylephrine in Bolus for Hypotension in Cesarean Delivery Phenylephrine 100 mcg, Norepinephrine 5 mcg - Hypotension, Spinal Anesthesia | Phase 2 | Completed | Hospital dos Servidores do Estado do Rio de Janeiro | 72 | 2018-10-01 | 2021-04-13 |
| Ephedrine and Phenylephrine for Spinal Hypotension Phenylephrine, Ephedrine - Spinal Hypotension | Phase 2 / Phase 3 | Completed | Assiut University | 60 | 2017-02-07 | 2020-10-27 |
| Phenylephrine and Noradrenaline for Post Spinal Anesthesia Hypotension phenylephrine, Norepinephrine, Bupivacaine - Adverse Anesthesia Outcome | Phase 2 | Completed | Kasr El Aini Hospital | 200 | 2017-01-01 | 2017-05-03 |
| Study of the Safety, Efficacy and PK of EYN-1601 in Dilation of the Pupil MDD-administered EYN-1601, Phenylephrine 2.5% Eyedrop, Phenylephrine 10% Eyedrop - Mydriasis | Phase 2 | Completed | Eyenovia Inc. | 12 | 2016-10-01 | 2022-07-27 |
| Phenylephrine and Hypotension During Spinal Anesthesia for Cesarean Section Phenylephrine, Placebo - Anesthesia, Obstetrical, Anesthesia, Spinal | Phase 2 | Completed | Assiut University | 980 | 2016-06-01 | 2017-05-18 |
| Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV Microneurography, Combat virtual reality video clip, Handgrip Exercise - Stress Disorders, Post-Traumatic | Phase 2 | Recruiting | Emory University | 134 | 2015-10-01 | 2026-05-18 |
| Target Hemodynamics and Brain Injury During General Anesthesia in the Elderly Hemodynamic target, Phenylephrine, Intravenous fluids - Post-operative Cognitive Dysfunction | Phase 2 / Phase 3 | Suspended | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 1812 | 2014-10-01 | 2018-04-13 |
| A Novel Closed-loop Integrated System for the Maintenance of Haemodynamic Stability vasopressor delivery automated system, phenylephrine, ephedrine - Hypotension | Phase 2 / Phase 3 | Completed | KK Women's and Children's Hospital | 252 | 2013-05-01 | 2026-08-07 |
| Closed-loop Double-vasopressor Automated System to Treat Hypotension During Spinal Anaesthesia for Caesarean Section Vasopressor automated delivery system, Phenylephrine, Ephedrine - Hypotension | Phase 2 / Phase 3 | Completed | KK Women's and Children's Hospital | 216 | 2011-10-01 | 2026-08-06 |
| Hemodynamics and Extravascular Lung Water in Acute Lung Injury Diuresis (furosemide) part I, Fluid Bolus (crystalloid or albumin), Vasopressors (Norepinephrine, Vasopressin, Phenylephrine, Epinephrine) - Acute Lung Injury | Phase 2 | Completed | Oregon Health and Science University | 33 | 2008-02-01 | 2019-09-10 |
| Phenylephrine in Septic Shock Phenylephrine, Norepinephrine - Septic Shock | Phase 2 | Completed | University of Roma La Sapienza | 32 | 2007-11-01 | 2017-10-26 |
| Phenylephrine Versus Norepinephrine in Septic Shock Phenylephrine - Septic Shock | Phase 2 | Completed | University of Roma La Sapienza | 15 | 2007-01-01 | 2007-06-01 |
| The Use of Nasal Phenylephrine in Infants With Bronchiolitis Phenylephrine - Bronchiolitis | Phase 2 | Completed | Akron Children's Hospital | 50 | 2005-01-01 | 2009-01-12 |
Showing 20 of 22. Sign in to see all of them.
Hypotension (6) · Shock, Septic (3) · Sepsis (2) · Acute Lung Injury (1) · Alopecia (1) · Bronchiolitis (1) · Cataract (1) · Cognitive Dysfunction (1) · Delirium (1) · Mitral Valve Insufficiency (1) · Mydriasis (1) · Respiratory Distress Syndrome (1) · Stress Disorders, Post-Traumatic (1) · Syncope (1) · Syncope, Vasovagal (1)
Assiut University (2) · KK Women's and Children's Hospital (2) · University of Roma La Sapienza (2) · Akron Children's Hospital (1) · Applied Biology, Inc. (1) · Carilion Clinic (1) · China International Neuroscience Institution (1) · Emory University (1) · Eyenovia Inc. (1) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (1) · Hospital dos Servidores do Estado do Rio de Janeiro (1) · Inder Paul Singh, M.D. (1) · Kasr El Aini Hospital (1) · King Faisal University (1) · Medical University of Vienna (1)
United States (7) · Egypt (3) · Italy (3) · Austria (1) · Brazil (1) · China (1) · Denmark (1) · Saudi Arabia (1) · Singapore (1)
Alessandro Santini, MD (1) · Andrea Morelli, M.D. (1) · Andrea Morelli, MD (1) · Andy Goren, MD (1) · Antonio Pesenti, MD (1) · Ban L Sng, FANZCA (1) · Ban Leong Sng, FANZCA (1) · Charles Phillips, M.D. (1) · Frank Biscardi (1) · Jeanie Park, MD (1) · Luciano Gattinoni, MD, FRCP (1) · Mads Rasmussen, MD, PhD (1) · Mario Garcia, MD (1)
PMID 19017409, PMID 24256483, PMID 29373334, PMID 30243062, PMID 32894044, PMID 34101716, PMID 40132839