16 completed, 3 terminated, 2 not yet recruiting, 2 recruiting. 26 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 26 | Completed 16, Terminated 3, Not yet recruiting 2, Recruiting 2, Unknown 2, Active not recruiting 1 |
Follow Nicotine Chewing Gum: new trials by email Literature Review of Nicotine Chewing Gum trials Research Report on Nicotine Chewing Gum
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Smoking Cessation Medication And Rewards Using a Teamlet to Treat Tobacco Use Disorder (SMARTTT 2.0) Among Persons With HIV: A Multi-site Hybrid Type 2 Effectiveness-implementation Trial nicotine patch, nicotine gum, nicotine lozenge, varenicline, bupropion, Multi-target Contingency Management, Teamlet booster - Tobacco Use Disorder/Cigarette Smoking, HIV | Phase 4 | Not yet recruiting | Yale University | 794 | 2027-09-30 | 2026-09-23 |
| Evaluating an Innovative Tobacco Treatment Approach for Veterans in Substance Use Treatment Healthy Changes Nicotine Replacement Therapy (NRT), Cessation Treatment Nicotine Replacement Therapy (NRT), Cessation Treatment Counseling - Cigarette Smoking, Veterans | Phase 4 | Not yet recruiting | VA Office of Research and Development | 112 | 2027-04-01 | 2026-09-14 |
| Varenicline for Smoking Reduction in Veterans Not Ready To Quit Motivation-Phase Varenicline, Motivation-Phase Nicotine Mini-Lozenge, Cessation-Phase Combination Nicotine Replacement Therapy (NRT) - Veterans, Tobacco Use Disorder | Phase 4 | Recruiting | VA Office of Research and Development | 400 | 2026-08-17 | 2026-08-31 |
| Smoking Cessation Program in the Construction Sector Nicorette, Tobacco Quit-line, Brief Behavioral Counseling - Smoking Cessation, Tobacco Use Cessation | Phase 4 | Active not recruiting | University of Miami | 608 | 2024-04-10 | 2026-08-21 |
| BREATHE 2 Clinic Stop-Smoking Treatment Outreach Study Text message smoking treatment, Nicotine replacement therapy sampling, Wisconsin Tobacco QuitLine Referral - Quitting Smoking, Smoking Cessation | Phase 4 | Completed | University of Wisconsin, Madison | 12376 | 2023-07-24 | 2026-06-26 |
| Smoking Cessation and Menstrual Cycle Phase Timing of nicotine replacement therapy start date, Nicotine Replacement Therapy Agent - Nicotine Dependence, Tobacco Smoking | Phase 4 | Recruiting | Centre for Addiction and Mental Health | 1200 | 2022-11-30 | 2026-03-19 |
| Research and Innovation to Stop E-cigarette/Vaping in Young Adults Nicotine patch, Phone Counseling, Digital Coaching - Nicotine Dependence, E-Cig Use | Phase 4 | Completed | Ohio State University | 508 | 2021-07-28 | 2024-07-29 |
| A Smart Approach to Treating Tobacco Use Disorder in Persons Living With HIV Nicotine patch, nicotine gum, nicotine nasal spray, nicotine inhaler, Varenicline or bupropion, Contingency Management - Tobacco Use Cessation | Phase 4 | Completed | Yale University | 323 | 2020-07-27 | 2026-01-05 |
| Smoking Cessation in Hispanic Construction Workers Nicorette Gum, Nicoderm CQ, Smoking Quitline Referral - Smoking Cessation | Phase 4 | Completed | University of Miami | 134 | 2017-04-13 | 2019-11-07 |
| Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia Nicotine replacement therapy, Bupropion, cognitive-behavioral smoking cessation counseling - Schizophrenia, Cigarette Smoking | Phase 4 | Completed | Duke University | 35 | 2017-03-27 | 2019-07-10 |
| Mobile Contingency Management for Concurrent Abstinence From Alcohol and Smoking Nicotine Replacement Therapy, Bupropion, Cognitive Behavioral Treatment - Smoking Cessation, Alcohol Drinking | Phase 4 | Completed | Duke University | 45 | 2016-11-01 | 2021-04-28 |
| Changing the Default for Tobacco Treatment Opt Out Treatment Program, Nicotine Replacement Therapy, Opt In Treatment Program - Tobacco Use Cessation | Phase 4 | Completed | University of Kansas Medical Center | 1000 | 2016-09-01 | 2022-12-01 |
| Effect of Smoking Reduction on Endothelial Glucocalyx and Vascular Function Varenicline, nicotine - Smoking Cessation | Phase 4 | Unknown | University of Athens | 600 | 2014-12-03 | 2020-04-03 |
| Abstinence Reinforcement Therapy (ART) for Homeless Veteran Smokers Nicotine Patches, mobile contingency management (mCM), Smoking cessation counseling - Tobacco Use Disorder, Homelessness | Phase 4 | Completed | VA Office of Research and Development | 133 | 2014-10-01 | 2022-01-04 |
| e-Cigarettes Versus NRT Gum for Smoking Cessation Nicotine polacrilex, STAM 1100mAh CE4 eGo Clearomizer - Nicotine Addiction, Smoking Cessation | Phase 4 | Terminated | Creighton University | 10 | 2013-08-01 | 2016-01-14 |
| Nicotine Gum Recovery After Colorectal Surgery Nicotine gum, Regular chewing gum - Post-operative Ileus | Phase 4 | Terminated | The Cleveland Clinic | 4 | 2012-08-01 | 2017-08-22 |
| Identifying Treatments to Motivate Smokers to Quit Nicotine Patch, Nicotine Gum, Motivational Interviewing - Smoking, Smoking Cessation | Phase 4 | Completed | University of Wisconsin, Madison | 517 | 2010-06-01 | 2015-12-16 |
| Improving the Population-Wide Effectiveness of U.S. Tobacco Cessation Quitlines Nicotine patch, Nicotine gum, CMAC - Smoking, Smoking Cessation | Phase 4 | Completed | University of Wisconsin, Madison | 987 | 2010-04-01 | 2016-12-08 |
| Effect of Daily Nicotine Patch Application on Mechanical Ventilation Weaning in Smoking Patients Nicotine patch, Placebo - Smoking, Mechanical Ventilation | Phase 4 | Unknown | University of Paris 5 - Rene Descartes | 600 | 2010-01-01 | 2010-04-16 |
| Evaluation of the Safety Profile, Quit and Reduction Rate After Nicorette® Gum and Patch Treatment Nicotine Gum, Nicotine Patch - Tobacco Dependence | Phase 4 | Completed | McNeil AB | 300 | 2009-02-01 | 2012-07-13 |
Showing 20 of 26. Sign in to see all of them.
Smoking Cessation (14) · Tobacco Use Disorder (10) · Cigarette Smoking (5) · Smoking (5) · Tobacco Use Cessation (4) · Schizophrenia (3) · Psychotic Disorders (2) · Substance-Related Disorders (2) · Tobacco Smoking (2) · Vaping (2) · Alcohol Drinking (1) · Alcoholism (1) · Ileus (1) · Medication Adherence (1) · Smoking Reduction (1)
University of Wisconsin, Madison (4) · Duke University (3) · VA Office of Research and Development (3) · Yale University (3) · McNeil AB (2) · University of Miami (2) · Centre for Addiction and Mental Health (1) · Creighton University (1) · National Institute on Drug Abuse (NIDA) (1) · North Suffolk Mental Health Association (1) · Ohio State University (1) · The Cleveland Clinic (1) · University of Athens (1) · University of Kansas Medical Center (1) · University of Paris 5 - Rene Descartes (1)
United States (21) · Canada (1) · China (1) · France (1) · Greece (1)
A Eden Evins, MD, MPH (2) · E. Jennifer Edelman, MD, MHS (2) · Taghrid Asfar, MD (2) · Amy J Arouni, MD (1) · Danielle E McCarthy, PhD (1) · David J Lee, PhD (1) · Didier Journois, M.D. Ph.D. (1) · Elisabeth A Kruse, PhD (1) · Elizabeth G Klein, PhD (1) · Eric A. Dedert, Ph.D. (1) · Evan Myers, MD, MPH (1) · George Pavlidis, MD (1) · Ignatios Ikonomidis, MD (1) · Jackie Mao (1)
PMID 37230961, PMID 17632223, PMID 17763111, PMID 17888856, PMID 19664750, PMID 22992296, PMID 28549278, PMID 28806908, PMID 29454141, PMID 31426671, PMID 33063570, PMID 33794354, PMID 35435813, PMID 36848129, PMID 37005655, PMID 37335995, PMID 39665734, PMID 40489501, PMID 41758512
1RC1CA144382-01 (1), P01CA180945 (1), P50CA143188 (1), R01AA011197 (1), R01CA243910 (1), R01HL131512 (1), R21CA202993 (1)