28 completed, 1 terminated. 17 Phase 3, 6 Phase 1, 2 Phase 2, 2 Phase 4.
By phase and status
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
A Study of Certolizumab Pegol to Evaluate Pharmacokinetics and Safety in Adult Healthy Chinese Subjects Certolizumab Pegol, Placebo - Healthy Subjects | Phase 1 | Completed | UCB Pharma SA | 36 | 2015-03-01 | 2015-08-14 |
An Open-label Extension Study of Certolizumab Pegol in Chinese Patients With Rheumatoid Arthritis Who Enrolled in RA0044 Certolizumab Pegol - Rheumatoid Arthritis | Phase 3 | Completed | UCB Pharma SA | 347 | 2014-11-01 | 2018-10-16 |
Single-site, Open-label, Randomized, Cross-over Study in Healthy Chinese Subjects to Evaluate the Bioequivalence of Single-dose Rotigotine Transdermal Patch Comparing 2 Different Formulations Rotigotine PR2.2.1, Rotigotine PR2.1.1 - Healthy | Phase 1 | Completed | UCB Pharma SA | 50 | 2014-02-01 | 2014-07-29 |
Bioavailability/Bioequivalence Study Between Lacosamide Tablet and Solution for Infusion in Healthy Japanese Subjects Lacosamide infusion, Lacosamide oral - Healthy Volunteers | Phase 1 | Completed | UCB Pharma SA | 26 | 2013-11-01 | 2014-09-12 |
Open-label, Randomized, Active-controlled Study of LEV Used as Monotherapy in Patients With Partial-Onset Seizures Levetiracetam, Carbamazepine - Epilepsy, Partial Seizures | Phase 3 | Completed | UCB Pharma SA | 436 | 2013-09-01 | 2017-08-15 |
Study to Evaluate the Safety, Tolerability, and Efficacy of Long-term Adjunctive Therapy With Lacosamide in Adults With Partial-onset Seizures Lacosamide - Epilepsy, Partial-onset Seizures | Phase 3 | Completed | UCB Pharma SA | 473 | 2013-03-26 | 2021-08-17 |
Comparison of Brivaracetam Oral Tablet (10 mg, 50 mg, 75 mg and 100 mg) and Brivaracetam Injection (100 mg) in Healthy Volunteers Brivaracetam 10 mg oral tablet, Brivaracetam 50 mg oral tablet, Brivaracetam 75 mg oral tablet - Healthy Volunteers | Phase 1 | Completed | UCB Pharma SA | 25 | 2013-01-01 | 2013-04-15 |
Noninterventional Examination of Subcutaneous (sc) Tumor Necrosis Factor (TNF) Inhibitors Rheumatoid Arthritis | | Completed | UCB Pharma SA | 1723 | 2012-12-01 | 2020-12-22 |
Scintigraphic Detection of the Biodistribution of Tumor Necrosis Factor With a Radiolabeled Anti-TNFα in Patients With Active Rheumatoid Arthritis and Active Axial and Peripheral Spondyloarthritis administration of Cimzia®, Immunoscintigraphy with radiolabeled Cimzia®. - Axial and Peripheral Spondyloarthritis, Rheumatoid Arthritis | Phase 3 | Completed | University Hospital, Ghent | 41 | 2012-10-18 | 2019-08-26 |
Evaluation of Long-term Safety, and Efficacy of Brivaracetam (BRV) Used as Adjunctive Treatment in Subjects With Epilepsy Brivaracetam - Epilepsy | Phase 3 | Completed | UCB Pharma SA | 26 | 2012-10-01 | 2018-07-11 |
A Trial to Evaluate the Efficacy and Safety of Adjunctive Therapy With Lacosamide in Adults With Partial-Onset Seizures Lacosamide 50 mg, Lacosamide 100 mg, Placebo - Epilepsy, Partial Onset Seizures | Phase 3 | Completed | UCB Pharma SA | 548 | 2012-09-01 | 2017-08-25 |
A Study to Investigate the Drug-Drug Interactions of Brivaracetam and Ethanol in Healthy Male Subjects Brivaracetam, Ethanol, Brivaracetam Placebo - Healthy Volunteers | Phase 1 | Completed | UCB Pharma SA | 18 | 2012-09-01 | 2018-10-11 |
Effect of Brivaracetam (BRV) on Nonpsychotic Behavioral Side Effects in Subjects Treated Previously With Levetiracetam (LEV) Brivaracetam - Epilepsy | Phase 3 | Completed | UCB Pharma SA | 29 | 2012-07-01 | 2018-07-11 |
Sleep Efficiency Assessed by Polysomnography (PSG Sleep Lab Testing) in Advanced Parkinson's Disease Placebo, Rotigotine - Advanced Idiopathic Parkinson's Disease | Phase 4 | Terminated | UCB Pharma SA | 1 | 2012-03-01 | 2025-04-03 |
Health-related Quality of Life and Patient-reported Outcomes in Rheumatoid Arthritis Patients Treated With Certolizumab Pegol Rheumatoid Arthritis | | Completed | UCB Pharma SA | 81 | 2012-01-01 | 2014-03-19 |
A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis Certolizumab Pegol, Placebo, Methotrexate - Rheumatoid Arthritis | Phase 3 | Completed | UCB Pharma SA | 880 | 2012-01-01 | 2026-08-25 |
Study to Assess the Short- and Long-term Efficacy of Certolizumab Pegol Plus Methotrexate Compared to Adalimumab Plus Methotrexate in Subjects With Moderate to Severe Rheumatoid Arthritis (RA) Inadequately Responding to Methotrexate Certolizumab Pegol (CZP), Adalimumab (ADA), Methotrexate (MTX) - Rheumatoid Arthritis | Phase 4 | Completed | UCB Pharma SA | 915 | 2011-12-01 | 2018-07-31 |
Open-label Long-term Study of Adjunctive Brivaracetam in Pediatric Subjects With Epilepsy Brivaracetam (BRV) - Epilepsy | Phase 3 | Completed | UCB Pharma SA | 257 | 2011-08-01 | 2025-10-20 |
Open-label Study of Levetiracetam Intravenous Infusion in Children (1 Month-4 Years Old) With Epilepsy Levetiracetam - Epilepsy | Phase 2 | Completed | UCB Pharma SA | 19 | 2008-05-01 | 2015-07-15 |
Brivaracetam as add-on Treatment in Adolescents and Adults Suffering From Epilepsy Placebo, Brivaracetam - Epilepsy | Phase 3 | Completed | UCB Pharma SA | 480 | 2007-10-01 | 2018-04-03 |
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Conditions studied
Epilepsy (11) · Arthritis, Rheumatoid (6) · Crohn Disease (2) · Asthma (1) · Dermatitis, Atopic (1) · Epilepsies, Partial (1) · Epilepsy, Generalized (1) · Epilepsy, Tonic-Clonic (1) · Myoclonic Epilepsies, Progressive (1) · Myoclonus (1) · Narcolepsy (1) · Seizures (1) · Sleep Wake Disorders (1) · Spondylarthritis (1) · Unverricht-Lundborg Syndrome (1)
Interventions
brivaracetam (8) · Certolizumab Pegol (6) · Levetiracetam (4) · Lacosamide (3) · Methotrexate (2) · Adalimumab (1) · Carbamazepine (1) · Ethanol (1) · Radioimmunodetection (1) · Seletracetam (1) · Sodium Oxybate (1) · Tablets (1) · levocetirizine (1) · rotigotine (1)
Countries
Germany (11) · Belgium (9) · Spain (9) · United States (9) · France (8) · Italy (8) · Czechia (7) · Hungary (7) · Poland (7) · United Kingdom (7) · China (6) · Austria (5) · Canada (5) · Netherlands (5) · Sweden (5)
Top investigators
Filip Van den Bosch, MD (1)
Results publications
PMID 33461041, PMID 26899665, PMID 28004320, PMID 35285519, PMID 20363366, PMID 22050371, PMID 23533164, PMID 23859801, PMID 24116853, PMID 24256083, PMID 26432008, PMID 26666500, PMID 27165179, PMID 27265725, PMID 27335114, PMID 27403334, PMID 27494777, PMID 27589414, PMID 27608437, PMID 27863807, PMID 27988967, PMID 28236727, PMID 28279891, PMID 28410341, PMID 28666080, PMID 29414542, PMID 29908435, PMID 30098648, PMID 32100960, PMID 32432339, PMID 34155568, PMID 34218211, PMID 34246118, PMID 35582748, PMID 37597326, PMID 38788664, PMID 39222436, PMID 40737960, PMID 42263998
NIH funding
2005 (3), 2004 (1), 2009 (1), 2014 (1)