9 completed, 2 active not recruiting, 2 terminated, 2 unknown. 17 Phase 2, 5 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 17 | Completed 9, Active not recruiting 2, Terminated 2, Unknown 2, Not yet recruiting 1, Recruiting 1 |
| Phase 3 | 5 | Active not recruiting 2, Completed 2, Recruiting 1 |
| Phase 1 | 1 | Unknown 1 |
Follow Haloperidol: new trials by email Literature Review of Haloperidol trials Research Report on Haloperidol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effectiveness of HP and TMZ Synergism on Adult Recurrence GBM Haloperidol Tablets, Temozolomide - Glioblastoma Multiforme | Phase 2 | Not yet recruiting | Southern Medical University, China | 200 | 2024-12-01 | 2024-01-23 |
| Comparative Efficacy of Dexamethasone - Ondansetron Versus Dexamethasone - Haloperidol in Reducing PONV Ondansetron, Haloperidol - Laparoscopic Cholecystectomy | Phase 2 | Completed | Universitas Padjadjaran | 38 | 2023-11-01 | 2024-05-24 |
| Combination of Haloperidol and Magnesium for Delirium Prevention in Critically Ill Elderly Haloperidol Injection - Delirium in Old Age | Phase 2 / Phase 3 | Completed | Ain Shams University | 135 | 2022-11-01 | 2023-12-13 |
| Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy Haloperidol, Chlorpromazine, Valproate - Delirium, Epileptics | Phase 2 / Phase 3 | Recruiting | M.D. Anderson Cancer Center | 42 | 2022-07-19 | 2025-11-18 |
| Meth-OD: A Study of IXT-m200 in Patients With Toxicity From Methamphetamine Overdose IXT-m200, Lorazepam, Haloperidol - Methamphetamine Intoxication (Disorder) | Phase 2 | Terminated | InterveXion Therapeutics, LLC | 20 | 2021-06-30 | 2023-11-18 |
| Study to Compare Clozapine vs Treatment as Usual in People With Intellectual Disability & Treatment-resistant Psychosis Clozapine, haloperidol, pimozide, olanzapine, risperidone, amisulpride - Psychosis, Intellectual Disability | Phase 2 | Unknown | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 75 | 2020-11-26 | 2024-03-20 |
| Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care Haloperidol, Lorazepam, Placebo - Delirium, Locally Advanced Malignant Neoplasm | Phase 2 / Phase 3 | Active not recruiting | M.D. Anderson Cancer Center | 110 | 2019-07-17 | 2026-06-15 |
| Rapid Agitation Control With Ketamine in the Emergency Department Ketalar, Midazolam injection, Haloperidol - Violent Aggressive Behavior, Ketamine | Phase 2 | Completed | David Barbic | 81 | 2018-05-29 | 2020-11-30 |
| Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer Chlorpromazine, Haloperidol, Quality-of-Life Assessment - Advanced Malignant Neoplasm, Delirium | Phase 2 / Phase 3 | Active not recruiting | M.D. Anderson Cancer Center | 70 | 2017-06-05 | 2026-09-14 |
| Antipsychotic Effects of Sorghum Bicolor (JOBELYN) in the Treatment of Schizophrenia Jobelyn, Haloperidol - Schizophrenia and Disorders With Psychotic Features | Phase 1 / Phase 2 | Unknown | Federal Neuro-Psychiatric Hospital, Yaba | 100 | 2017-06-01 | 2017-02-16 |
| D1 and D2 Dopamine Receptors in Gambling and Amphetamine Reinforcement Haloperidol, Fluphenazine, Dexedrine - Pathological Gambling | Phase 2 | Completed | Centre for Addiction and Mental Health | 60 | 2009-09-01 | 2016-04-25 |
| Study of Preladenant for the Treatment of Neuroleptic Induced Akathisia (Study P05145) Preladenant, Placebo, Anticholinergic agents or propanolol - Akathisia, Drug-Induced, Antipsychotic Agents | Phase 2 | Terminated | Merck Sharp & Dohme LLC | 46 | 2007-08-15 | 2018-11-07 |
| Pilot Study of Haloperidol to Treat Critical Illness Delirium Haloperidol - Delirium, Critical Illness | Phase 2 | Completed | University of Colorado, Denver | 20 | 2005-12-01 | 2012-11-14 |
| A Comparison of Dexmedetomidine and Haloperidol in Patients With Intensive Care Unit (ICU)-Associated Agitation and Delirium dexmedetomidine, haloperidol - Delirium, Agitation | Phase 2 | Completed | Austin Health | 20 | 2005-01-01 | 2013-01-24 |
| The MIND Study: Modifying the INcidence of Delirium Ziprasidone, Haloperidol, Placebo - Delirium, Cognition Disorders | Phase 2 | Completed | Vanderbilt University | 102 | 2004-12-01 | 2016-01-29 |
| Ziprasidone vs. Sertraline/Haloperidol in Psychotic Depression Ziprasidone, Sertraline, Haloperidol - Affective Disorders | Phase 2 / Phase 3 | Completed | Duke University | 72 | 2003-04-01 | 2014-08-19 |
| A Comparison of Study Drug With Placebo and Haloperidol in Patients With Schizophrenia Lurasidone 20 mg, Lurasidone 40mg, Lurasidone 80 mg - Schizophrenia | Phase 2 | Completed | Sumitomo Pharma America, Inc. | 356 | 2002-07-01 | 2014-04-17 |
Delirium (6) · Critical Illness (2) · Neoplasm Metastasis (2) · Recurrence (2) · Aggression (1) · Akathisia, Drug-Induced (1) · Cognition Disorders (1) · Emergencies (1) · Epilepsy (1) · Gambling (1) · Glioblastoma (1) · Intellectual Disability (1) · Mental Disorders (1) · Mood Disorders (1) · Movement Disorders (1)
M.D. Anderson Cancer Center (3) · Ain Shams University (1) · Austin Health (1) · Centre for Addiction and Mental Health (1) · David Barbic (1) · Duke University (1) · Federal Neuro-Psychiatric Hospital, Yaba (1) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (1) · InterveXion Therapeutics, LLC (1) · Merck Sharp & Dohme LLC (1) · Southern Medical University, China (1) · Sumitomo Pharma America, Inc. (1) · Universitas Padjadjaran (1) · University of Colorado, Denver (1) · Vanderbilt University (1)
United States (8) · Canada (2) · Egypt (2) · Brazil (1) · India (1) · Indonesia (1) · Nigeria (1) · Spain (1)
David Hui (2) · Adel Elsheshai, MD (1) · Benedicto Crespo Facorro, Professor (1) · Daniela Lobo, MD, Ph.D. (1) · David Barbic, MD MSc FRCPC, (1) · David Hui, MD (1) · Dian Mardiani, M.D (1) · E Wesley Ely, MD, MPH (1) · Frederick Cassidy, MD (1) · George Simpson, MD (1) · Ivor S Douglas, MD (1) · Michael C Reade, MBBS FJFICM (1)
PMID 19454032, PMID 20095068, PMID 30477544, PMID 32479786, PMID 36919514, PMID 37249604, PMID 38807685, PMID 39831535, PMID 40742738
R21NR016736 (1), U01DA053043 (1)