6 completed, 2 terminated, 1 active not recruiting, 1 unknown. 10 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 6, Terminated 2, Active not recruiting 1, Unknown 1 |
| Phase 3 | 3 | Completed 2, Unknown 1 |
Follow Glycine: new trials by email Literature Review of Glycine trials Research Report on Glycine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Nasal Treatment for COVID-19 Optate, Placebo - COVID-19, Healthy | Phase 2 | Active not recruiting | Indiana University | 24 | 2023-06-27 | 2026-05-28 |
| The Effects of Glycine on Atherosclerosis and Metabolic Syndrome-related Parameters. Glycine - Metabolic Syndrome, Dyslipidemias | Phase 2 / Phase 3 | Unknown | Prof. Tony hayek MD | 50 | 2019-03-01 | 2019-02-21 |
| Neurobiology of a Mutation in Glycine Metabolism in Psychotic Disorders Glycine, placebo - Schizo-affective Disorder, Bipolar Disorder | Phase 2 | Completed | Mclean Hospital | 2 | 2012-12-10 | 2017-09-19 |
| Effect of Glycine in Cystic Fibrosis Glycine, Placebo - Cystic Fibrosis | Phase 2 | Terminated | Instituto Nacional de Enfermedades Respiratorias | 13 | 2012-03-01 | 2014-11-05 |
| A Randomized Double-Blind Control-Comparison Crossover Trial of Oral Glutamine to Suppress Frequently Recurrent Herpes Labialis Glutamine, Glycine - Herpes Labialis, Herpes Simplex Virus | Phase 2 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 11 | 2009-06-01 | 2012-06-11 |
| Glycine vs Placebo for the Schizophrenia Prodrome Glycine, Placebo - Schizophrenia Prodrome | Phase 2 / Phase 3 | Completed | Yale University | 8 | 2006-03-01 | 2020-04-02 |
| Facilitation of NMDA Receptor Function in Patients With Schizophrenia and Co-morbid Alcoholism Glycine, placebo - Alcoholism, Schizophrenia | Phase 2 | Completed | Yale University | 20 | 2003-06-01 | 2018-01-17 |
| Glycine Treatment of Prodromal Symptoms glycine - Schizophrenia | Phase 2 | Completed | Yale University | 10 | 2002-07-01 | 2012-03-29 |
| Glycine to Treat Psychotic Disorders in Children Glycine - Psychotic Disorder, Schizoaffecitve Disorder | Phase 2 | Completed | National Institute of Mental Health (NIMH) | 10 | 2000-05-01 | 2008-03-04 |
| Adjunctive Treatment for Decreasing Symptoms of Schizophrenia d-cycloserine, glycine, placebo - Schizophrenia, Schizoaffective Disorder | Phase 2 / Phase 3 | Completed | University of Maryland, Baltimore | 240 | 2000-01-01 | 2019-08-20 |
Schizophrenia (4) · Psychotic Disorders (3) · Alcoholism (1) · Atherosclerosis (1) · Bipolar Disorder (1) · COVID-19 (1) · Cognitive Dysfunction (1) · Cystic Fibrosis (1) · Diabetes Mellitus (1) · Dyslipidemias (1) · Herpes Labialis (1) · Herpes Simplex (1) · Hyperglycinemia, Nonketotic (1) · Metabolic Syndrome (1) · Obesity (1)
Yale University (3) · Indiana University (1) · Instituto Nacional de Enfermedades Respiratorias (1) · Mclean Hospital (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · National Institute of Mental Health (NIMH) (1) · Prof. Tony hayek MD (1) · University of Maryland, Baltimore (1)
United States (7) · Israel (1) · Mexico (1)
Scott W Woods, MD (2) · Deborah L Levy, PhD (1) · Ismene Petrakis, M.D. (1) · Mario H Vargas, MD, MSc (1) · Tony Hayek, MD (1) · William T Carpenter, MD (1)
PMID 23089076, PMID 17898352, PMID 29246256, PMID 31279534
R01MH059807 (1), R21MH097470 (1)