45 completed, 9 terminated, 6 unknown, 4 recruiting. 18 Phase 4, 17 Phase 2, 13 Phase 3, 11 Not applicable, 10 Phase 1.
Follow Cozaar: new trials by email Literature Review of Cozaar trials Research Report on Cozaar
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD) Finerenone, Semaglutide, Lotensin - Chronic Kidney Disease, Type 2 Diabetes | Phase 4 | Enrolling by invitation | Baylor Research Institute | 64 | 2026-04-08 | 2026-10-13 |
| The Effect of Losartan on Cephalexin losartan, cephalexin - Possible Interaction Between Losartan and Cephalexin, Healthy | Phase 1 | Completed | Aleksi Tornio | 13 | 2026-03-04 | 2026-10-01 |
| Losartan and Social Processing Losartan potassium 50mg, Placebo - Social Cognition | Early Phase 1 | Completed | University of Oxford | 68 | 2024-08-19 | 2026-09-24 |
| A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial) Losartan, Amlodipine, Placebo - Coarctation of Aorta, High Blood Pressure | Phase 3 | Recruiting | Mayo Clinic | 120 | 2024-04-01 | 2026-09-11 |
| The Effects of Losartan on Attention Control: An Eye-tracking Study Losartan, Placebo - Healthy | Not applicable | Unknown | University of Electronic Science and Technology of China | 80 | 2024-03-05 | 2024-04-11 |
| Losartan Modulates Neural Responses to Looming Visual Stimuli: An Eye-tracking Study Losartan, Placebo - Healthy | Not applicable | Unknown | University of Electronic Science and Technology of China | 80 | 2024-03-05 | 2024-04-11 |
| FOLFIRINOX + Elraglusib + Losartan In Pancreatic Cancer FOLFIRNINOX, Losartan, 9-ING-41 - Pancreatic Adenocarcinoma, Pancreatic Adenocarcinoma Metastatic | Phase 2 | Active not recruiting | Colin D. Weekes, M.D., PhD | 70 | 2022-03-21 | 2026-09-11 |
| Effect of Losartan in Cystic Fibrosis (CF)-NIH Grant #133240 Losartan - Cystic Fibrosis | Early Phase 1 | Completed | University of Kansas Medical Center | 13 | 2022-02-15 | 2026-05-01 |
| NeoOPTIMIZE: Early Switching of mFOLFIRINOX or Gemcitabine/Nab-Paclitaxel Before Surgery for the Treatment of Resectable, Borderline Resectable, or Locally-Advanced Unresectable Pancreatic Cancer Capecitabine, Fluorouracil, Irinotecan Hydrochloride - Pancreatic Adenocarcinoma, Stage 0 Pancreatic Cancer American Joint Committee on Cancer v8 | Phase 2 | Active not recruiting | OHSU Knight Cancer Institute | 42 | 2021-05-27 | 2026-01-14 |
| Secondhand Tobacco Smoke and Cardiovascular Disease Losartan, Placebo - Cardiovascular Diseases, Hypertension | Phase 4 | Recruiting | University of California, San Francisco | 100 | 2021-03-30 | 2026-08-19 |
| Renohemodynamic Effects of Combined empagliflOzin and LosARtan Empagliflozin 10 MG, Losartan 50Mg Tab, Placebo - Diabetes Mellitus, Type 2, Diabetic Kidney Disease | Phase 4 | Completed | Amsterdam UMC, location VUmc | 24 | 2020-11-04 | 2021-10-08 |
| Host Response Mediators in Coronavirus (COVID-19) Infection - Is There a Protective Effect of Losartan and Other ARBs on Outcomes of Coronavirus Infection? Losartan, Valsartan, Azilsartan - Covid19, SARS-CoV Infection | Phase 3 | Terminated | University of British Columbia | 341 | 2020-10-09 | 2023-02-16 |
| Losartan for Patients With COVID-19 Requiring Hospitalization Losartan, Placebo - Corona Virus Infection, Acute Respiratory Distress Syndrome | Phase 2 | Completed | University of Minnesota | 205 | 2020-04-13 | 2022-06-29 |
| Losartan for Patients With COVID-19 Not Requiring Hospitalization Losartan, Placebo - Corona Virus Infection, Acute Respiratory Distress Syndrome | Phase 2 | Completed | University of Minnesota | 117 | 2020-04-09 | 2022-05-04 |
| COVID MED Trial - Comparison Of Therapeutics for Hospitalized Patients Infected With COVID-19 Losartan, Placebo - SARS-CoV-2 Infection | Phase 2 / Phase 3 | Terminated | Bassett Healthcare | 15 | 2020-04-06 | 2022-03-24 |
| Study of Open Label Losartan in COVID-19 Losartan - COVID-19 | Phase 1 | Completed | University of Kansas Medical Center | 34 | 2020-04-04 | 2024-08-02 |
| Chinese Medicine Treat for Hypertensive Renal Injury Losartan 100Mg Tab, Qianyangyuyin 20g Granule, placebo - Hypertension, Renal Injury | Phase 2 / Phase 3 | Unknown | Jiangsu Province Hospital of Traditional Chinese Medicine | 520 | 2019-09-10 | 2019-09-06 |
| Losartan and Hypofractionated Rx After Chemo for Tx of Borderline Resectable or Locally Advanced Pancreatic Cancer Hypofractionated Radiation Therapy, Losartan, Losartan Potassium - Borderline Resectable Pancreatic Adenocarcinoma, Locally Advanced Pancreatic Ductal Adenocarcinoma | Phase 1 | Completed | University of Utah | 22 | 2019-08-08 | 2026-07-06 |
| Nighttime Losartan in Continous Ambulatory Peritoneal Dialysis (NVCAPD) Losartan - Hypertension,Nephropathy | Phase 4 | Unknown | Fifth Affiliated Hospital, Sun Yat-Sen University | 68 | 2018-12-01 | 2018-11-05 |
| AT1R Blockade and Periodic Breathing During Sleep in Hypoxia Hyperoxic Hypercapnic Ventilatory Response Test, Hypoxic Hypercapnic Ventilatory Response Test, Repeated Hypoxic Apneas - Sleep Disordered Breathing, Hypoxia | Phase 4 | Completed | University of British Columbia | 14 | 2018-01-01 | 2020-09-04 |
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Hypertension (21) · COVID-19 (5) · Coronavirus Infections (4) · Diabetic Nephropathies (4) · Proteinuria (4) · Diabetes Mellitus, Type 2 (3) · Kidney Diseases (3) · Renal Insufficiency, Chronic (3) · Respiratory Distress Syndrome (3) · Severe Acute Respiratory Syndrome (3) · Bronchitis, Chronic (2) · Cardiovascular Diseases (2) · Cystic Fibrosis (2) · Essential Hypertension (2) · Glomerulonephritis, IGA (2)
University of Minnesota (3) · Brigham and Women's Hospital (2) · Emory University (2) · Massachusetts General Hospital (2) · Mayo Clinic (2) · Organon and Co (2) · Roxane Laboratories (2) · Seoul National University Hospital (2) · University of British Columbia (2) · University of California, San Francisco (2) · University of Electronic Science and Technology of China (2) · University of Kansas Medical Center (2) · University of Miami (2) · Vanderbilt University (2) · Aleksi Tornio (1)
United States (42) · China (5) · Canada (4) · South Korea (4) · Brazil (2) · Sweden (2) · Argentina (1) · Belgium (1) · Bulgaria (1) · Colombia (1) · Egypt (1) · Finland (1) · France (1) · Hungary (1) · Iran (1)
Benjamin Becker, Dr (2) · Christopher Tignanelli, MD (2) · Dennis N. Morrison, D.O. (2) · Hee Gyung Kang, Ph.D (2) · Italo Biaggioni, MD (2) · Mark A Creager, MD (2) · Matthias Salathe, MD (2) · Michael Puskarich, MD, MS (2) · Ahmed Shokier (1) · Aleksi Tornio, M.D., Ph.D. (1) · Alexander Egbe, MBBS, MPH (1) · Alireza Esteghamati, MD (1) · Anna Booher, MD (1) · Anthony J Viera, MD, MPH (1)
PMID 32658300, PMID 38682786, PMID 10851208, PMID 11927799, PMID 12119802, PMID 12923400, PMID 15738343, PMID 16391172, PMID 16533484, PMID 18426998, PMID 19047577, PMID 19738158, PMID 21130977, PMID 21861845, PMID 22718189, PMID 22763801, PMID 22801444, PMID 23266540, PMID 23545707, PMID 23622922, PMID 24621999, PMID 24875194, PMID 25405392, PMID 26414380, PMID 26465872, PMID 27548072, PMID 27612501, PMID 28395659, PMID 29948025, PMID 29992039, PMID 30541065, PMID 30859504, PMID 31573977, PMID 32410951, PMID 34027894, PMID 34195577, PMID 34275593, PMID 34437304, PMID 34473343, PMID 35229827, PMID 35294537, PMID 38299639, PMID 38770818, PMID 39325643, PMID 41734211, PMID 42158940, PMID 42442666, PMID 42492489, PMID 42745010, PMID 9369256
2025 (1), P50HL084945 (1), R01HL133240 (1), R01HL139365 (1), R01HL162830 (1), R03DK096157 (1), U01AG050499 (1), U01AI105872 (1), U01HL068270 (1), U54RR014616 (1)