11 completed, 3 unknown, 1 enrolling by invitation, 1 recruiting. 18 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 18 | Completed 11, Unknown 3, Enrolling by invitation 1, Recruiting 1, Terminated 1, Withdrawn 1 |
Follow Cozaar: new trials by email Literature Review of Cozaar trials Research Report on Cozaar
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD) Finerenone, Semaglutide, Lotensin - Chronic Kidney Disease, Type 2 Diabetes | Phase 4 | Enrolling by invitation | Baylor Research Institute | 64 | 2026-04-08 | 2026-10-13 |
| Secondhand Tobacco Smoke and Cardiovascular Disease Losartan, Placebo - Cardiovascular Diseases, Hypertension | Phase 4 | Recruiting | University of California, San Francisco | 100 | 2021-03-30 | 2026-08-19 |
| Renohemodynamic Effects of Combined empagliflOzin and LosARtan Empagliflozin 10 MG, Losartan 50Mg Tab, Placebo - Diabetes Mellitus, Type 2, Diabetic Kidney Disease | Phase 4 | Completed | Amsterdam UMC, location VUmc | 24 | 2020-11-04 | 2021-10-08 |
| Nighttime Losartan in Continous Ambulatory Peritoneal Dialysis (NVCAPD) Losartan - Hypertension,Nephropathy | Phase 4 | Unknown | Fifth Affiliated Hospital, Sun Yat-Sen University | 68 | 2018-12-01 | 2018-11-05 |
| AT1R Blockade and Periodic Breathing During Sleep in Hypoxia Hyperoxic Hypercapnic Ventilatory Response Test, Hypoxic Hypercapnic Ventilatory Response Test, Repeated Hypoxic Apneas - Sleep Disordered Breathing, Hypoxia | Phase 4 | Completed | University of British Columbia | 14 | 2018-01-01 | 2020-09-04 |
| Phase 4, Vedolizumab-4002 Post-marketing, Disease-Drug-Drug Interaction Study Caffeine, Losartan, Omeprazole - Colitis, Ulcerative, Crohn Disease | Phase 4 | Withdrawn | Takeda | 2016-11-01 | 2020-10-27 | |
| Effect of Losartan on Airway Mucociliary Dysfunction in Patients With COPD and Chronic Bronchitis Losartan 50 mg, Losartan 100 mg - COPD, Chronic Bronchitis | Phase 4 | Terminated | University of Miami | 31 | 2016-03-31 | 2020-08-20 |
| Add-on Pentoxifylline to Losartan Versus Increasing Dose of Losartan on NT-PRO BNP in Type 2 Diabetics With Nephropathy Pentoxifylline, Losartan - Diabetic Nephropathies | Phase 4 | Completed | Tehran University of Medical Sciences | 59 | 2015-04-01 | 2016-12-30 |
| Comparison of Blood Pressure Lowering Effect Between Fimasartan and Losartan Fimasartan, Losartan - Hypertension | Phase 4 | Unknown | Chuncheon Sacred Heart Hospital | 40 | 2014-11-01 | 2016-11-08 |
| Efficacy and Safety of Abelmoschus Manihot for IgA Nephropathy Losartan, Abelmoschus manihot - IgA Nephropathy | Phase 4 | Unknown | Chen Xiangmei | 1600 | 2014-09-01 | 2016-07-06 |
| Comparision of Blood Pressure Variability Between Amlodipine and Losartan Amlodipine, Losartan - Hypertension | Phase 4 | Completed | Wonju Severance Christian Hospital | 144 | 2013-04-01 | 2017-05-12 |
| Comparison Between Losartan and Benazepril in Diabetic Hypertensive Patients Not Controlled by Amlodipine Benazepril, Losartan - Hypertension, Diabetes Mellitus | Phase 4 | Completed | Hospital Universitario Pedro Ernesto | 30 | 2012-05-01 | 2016-02-01 |
| Olmesartan Comparison to Losartan in Hypertensive Subjects olmesartan medoxomil, Placebo, losartan potassium - Hypertension | Phase 4 | Completed | Daiichi Sankyo | 941 | 2009-08-01 | 2011-03-09 |
| Aliskiren Combined With Losartan in Proteinuric, Non-diabetic Chronic Kidney Disease Aliskiren, Losartan - Kidney Disease | Phase 4 | Completed | The University of Hong Kong | 80 | 2009-07-01 | 2015-07-03 |
| Efficacy of Losartan in Preventing Progression of COPD Losartan, Placebo - COPD, Emphysema | Phase 4 | Completed | Johns Hopkins University | 106 | 2008-07-01 | 2017-04-25 |
| Losartan in Hypertensive Men and Women With Sleep Apnea Before and on Continuous Positive Airway Pressure (CPAP) Treatment Losartan, CPAP - Hypertension, Sleep Apnea | Phase 4 | Completed | Skaraborg Hospital | 90 | 2008-06-01 | 2020-10-22 |
| A Randomized Clinical Trial To Study Losartan On Endothelial Dysfunction and Insulin Resistance In Obese Patients losartan, Placebo control - Obesity, Hypertension | Phase 4 | Completed | Brigham and Women's Hospital | 53 | 2007-05-01 | 2018-09-06 |
| The Effects of Angiotensin II Receptor Blockade on Kidney Function and Scarring After Liver Transplant Cozaar - Liver Transplant Recipients | Phase 4 | Completed | Mayo Clinic | 62 | 2004-12-01 | 2012-01-06 |
Hypertension (7) · Bronchitis, Chronic (2) · Diabetes Mellitus, Type 2 (2) · Diabetic Nephropathies (2) · Proteinuria (2) · Pulmonary Disease, Chronic Obstructive (2) · Sleep Apnea Syndromes (2) · Albuminuria (1) · Cardiovascular Diseases (1) · Colitis, Ulcerative (1) · Crohn Disease (1) · Diabetes Mellitus (1) · Emphysema (1) · Glomerulonephritis, IGA (1) · Hyperglycemia (1)
Amsterdam UMC, location VUmc (1) · Baylor Research Institute (1) · Brigham and Women's Hospital (1) · Chen Xiangmei (1) · Chuncheon Sacred Heart Hospital (1) · Daiichi Sankyo (1) · Fifth Affiliated Hospital, Sun Yat-Sen University (1) · Hospital Universitario Pedro Ernesto (1) · Johns Hopkins University (1) · Mayo Clinic (1) · Skaraborg Hospital (1) · Takeda (1) · Tehran University of Medical Sciences (1) · The University of Hong Kong (1) · University of British Columbia (1)
United States (8) · China (2) · Brazil (1) · Canada (1) · Iran (1) · Netherlands (1) · South Korea (1) · Sweden (1)
Alireza Esteghamati, MD (1) · Byung-Su Yoo, MD, PhD (1) · Cheng Wang, Director (1) · Daniel van Raalte, MD PhD (1) · Glen Foster, PhD (1) · K.V. Narayanan Menon, M.D. (1) · Mario F Neves, MD, DSc. (1) · Mark A Creager, MD (1) · Mehrdad Arjomandi, MD (1) · Rafael Calderon, MD (1) · Robert A. Wise, MD (1) · Ronaldo A Gismondi, MD, MSc. (1) · Sydney CW Tang, MD (1)
PMID 21861845, PMID 22763801, PMID 26414380, PMID 26465872, PMID 27548072, PMID 28395659, PMID 32410951, PMID 38299639, PMID 38682786, PMID 38770818, PMID 42492489
P50HL084945 (1), R01HL133240 (1), R01HL139365 (1)