7 completed, 2 terminated, 1 suspended. 10 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 7, Terminated 2, Suspended 1 |
| Phase 2 | 3 | Completed 1, Suspended 1, Terminated 1 |
Follow Cozaar: new trials by email Literature Review of Cozaar trials Research Report on Cozaar
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Losartan on Cephalexin losartan, cephalexin - Possible Interaction Between Losartan and Cephalexin, Healthy | Phase 1 | Completed | Aleksi Tornio | 13 | 2026-03-04 | 2026-10-01 |
| Study of Open Label Losartan in COVID-19 Losartan - COVID-19 | Phase 1 | Completed | University of Kansas Medical Center | 34 | 2020-04-04 | 2024-08-02 |
| Losartan and Hypofractionated Rx After Chemo for Tx of Borderline Resectable or Locally Advanced Pancreatic Cancer Hypofractionated Radiation Therapy, Losartan, Losartan Potassium - Borderline Resectable Pancreatic Adenocarcinoma, Locally Advanced Pancreatic Ductal Adenocarcinoma | Phase 1 | Completed | University of Utah | 22 | 2019-08-08 | 2026-07-06 |
| Pilot Trial: the Safety and Feasibility of Losartan for Pulmonary Vein Stenosis Losartan - Pulmonary Vein Stenosis, Children | Phase 1 / Phase 2 | Suspended | The Hospital for Sick Children | 40 | 2016-05-01 | 2019-07-30 |
| Pilot Study of Losartan and N-acetylcysteine as Inhibitors of Muscle Oxidative Stress in Elderly N-acetylcysteine, Losartan, Placebo losartan - Aging | Phase 1 / Phase 2 | Completed | The University of Texas Medical Branch, Galveston | 6 | 2011-07-01 | 2018-05-08 |
| Contribution of Angiotensin II to Supine Hypertension in Autonomic Failure Losartan, Captopril, Placebo - Hypertension, Pure Autonomic Failure | Phase 1 | Terminated | Vanderbilt University | 12 | 2011-03-01 | 2018-08-24 |
| Pharmacokinetic Study in Patients With Chronic Kidney Disease and Healthy Volunteers Propranolol, Losartan, Eprosartan - Kidney Disease | Phase 1 | Completed | University of California, San Francisco | 24 | 2010-03-01 | 2013-05-30 |
| Pilot Study of a Multi-Drug Regimen for Severe Pulmonary Fibrosis in Hermansky-Pudlak Syndrome Losartan, Zileuton, N-Acetylcysteine - Hermansky-Pudlak Syndrome (HPS), Pulmonary Fibrosis | Phase 1 / Phase 2 | Terminated | National Human Genome Research Institute (NHGRI) | 3 | 2007-04-01 | 2013-08-02 |
| The Effect of Losartan and Losartan Plus Isosorbide Mononitrate on Central Blood Pressure Measurements (0954-317) losartan potassium, Comparator: isosorbide mononitrate (ISMN), Comparator: losartan + ISMN - Hypertension | Phase 1 | Completed | Organon and Co | 13 | 2006-08-01 | 2022-02-09 |
| Treatment of Supine Hypertension in Autonomic Failure Clonidine, Nitroglycerin transdermal, Dipyridamole/ Aspirin (Aggrenox) - Hypertension | Phase 1 | Completed | Vanderbilt University | 152 | 2001-01-01 | 2017-10-13 |
Hypertension (3) · Multiple System Atrophy (2) · Pure Autonomic Failure (2) · Albinism (1) · Albinism, Oculocutaneous (1) · COVID-19 (1) · Hermanski-Pudlak Syndrome (1) · Kidney Diseases (1) · Lung Diseases (1) · Metabolic Diseases (1) · Pancreatic Neoplasms (1) · Platelet Storage Pool Deficiency (1) · Pulmonary Fibrosis (1) · Respiratory Insufficiency (1) · Shy-Drager Syndrome (1)
Vanderbilt University (2) · Aleksi Tornio (1) · National Human Genome Research Institute (NHGRI) (1) · Organon and Co (1) · The Hospital for Sick Children (1) · The University of Texas Medical Branch, Galveston (1) · University of California, San Francisco (1) · University of Kansas Medical Center (1) · University of Utah (1)
United States (7) · Canada (1) · Finland (1)
Italo Biaggioni, MD (2) · Aleksi Tornio, M.D., Ph.D. (1) · Astrid M Horstman, PhD (1) · Christopher A Caldarone, MD (1) · Leslie Z Benet, PhD (1) · Lynda Frassetto, MD (1) · Matthias Salathe (1) · Melinda Sheffield-Moore, PhD (1) · Shane Lloyd (1) · Thomas Markello, M.D. (1)
PMID 10851208, PMID 11927799, PMID 12119802, PMID 12923400, PMID 15738343, PMID 16391172, PMID 16533484, PMID 18426998, PMID 19047577, PMID 19738158, PMID 21130977, PMID 22801444, PMID 23266540, PMID 32658300, PMID 9369256, PMID 9890307
2025 (1)