91 completed, 15 recruiting, 11 active not recruiting, 9 unknown. 100 Not applicable, 16 Phase 2, 13 Phase 1, 13 Phase 3, 6 Phase 4.
Follow Cognitive Behavioral Therapy (CBT): new trials by email Literature Review of Cognitive Behavioral Therapy (CBT) trials Research Report on Cognitive Behavioral Therapy (CBT)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multi-site Feasibility of an Integrated Treatment for the Biology and Experience of Depression: The MULTIBED Study Cognitive Behavioral Therapy (CBT), Whole-Body Hyperthermia - Major Depressive Disorder | Not applicable | Not yet recruiting | University of California, San Francisco | 60 | 2026-12-01 | 2026-10-13 |
| Modality Choice Before and After Failure for the Treatment of Painful Diabetic Neuropathy Cognitive Behavioral Therapy (CBT), Oral Medication, Topical Medication - Painful Diabetic Neuropathy (PDN), Diabetic Nephropathies | Phase 4 | Not yet recruiting | University of Michigan | 600 | 2026-11-01 | 2026-10-21 |
| A Two-Part Intervention to Target Cardiovascular Health Lifestyle Medicine, Cognitive Behavioral Therapy (CBT), Lifestyle Medicine with CBT Group - Autism, Adverse Childhood Experience | Not applicable | Enrolling by invitation | University of California, Los Angeles | 130 | 2026-08-05 | 2026-09-11 |
| Project Q: Cue-based Treatment Intervention to Promote Cessation Among People Who Smoke Lightly or Non-daily Cognitive Behavioral Therapy (CBT), Cue-based treatment intervention - Tobacco Use Disorder | Not applicable | Recruiting | Duke University | 60 | 2026-07-07 | 2026-10-21 |
| Effectiveness of Acceptance and Commitment Therapy for Chronic Non-Malignant Pain: A Randomized Controlled Trial Acceptance and Commitment Therapy (ACT), Cognitive Behavioral Therapy (CBT) - Chronic Non-Malignant Pain (Chronic Musculoskeletal Pain, Chronic Widespread Pain) | Not applicable | Active not recruiting | GIFT University | 60 | 2026-05-13 | 2026-07-16 |
| Brief Cognitive Behavioral Therapy for Suicide Prevention in a Brazilian Sample: a Study Protocol of a Randomized Clinical Trial Brief Cognitive-Behavioral Therapy (BCBT) for Suicide Prevention, Supportive Therapy - Suicide Ideation, Suicide Attempts | Phase 3 | Not yet recruiting | University of Sao Paulo | 150 | 2026-05-10 | 2026-05-08 |
| Adapting and Implementing a Nurse Care Management Model to Care for Rural Patients With Chronic Pain Cognitive Behavioral Therapy (CBT), Exercise Counseling and tele-EnhanceFitness, Care Coordination - Chronic Pain | Not applicable | Enrolling by invitation | University of Washington | 450 | 2026-04-01 | 2026-04-27 |
| Psychological Options for Wellness and Recovery (POWeR) Trial for Veterans With Chronic Back/Neck Pain Pain reprocessing therapy (PRT), Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), Usual Care - Chronic Pain, Back Pain | Not applicable | Recruiting | University of Colorado, Denver | 360 | 2026-03-27 | 2026-03-31 |
| AI-Guided CBT for Depression and Anxiety AI-Guided Cognitive Behavioral Therapy, Cognitive Behavioral Therapy (CBT) - Depression - Major Depressive Disorder, Anxiety Disorders | Not applicable | Recruiting | Aleksandra Stojanovic | 120 | 2026-01-07 | 2026-05-08 |
| CBT, Breathing Exercises, and Psychoeducation on Tinnitus-Related Distress Cognitive Behavioral Therapy (CBT), 4-7-8 Breathing Exercise, Psychoeducation - Tinnitus | Not applicable | Completed | Ege University | 70 | 2026-01-05 | 2026-09-09 |
| Virtual Reality Treatment for Trauma Related to COVID-19 Infection VR Exposure Therapy, Cognitive Behavioral Therapy (CBT), Supportive Psychotherapy - PTSD, PTSD Symptoms | Not applicable | Not yet recruiting | Soonchunhyang University Hospital | 100 | 2025-11-01 | 2025-10-09 |
| Effect of Cognitive Behavioral Therapy on Auditory Hallucinations and NLR in Schizophrenia Patients Cognitive Behavioral Therapy (CBT), risperidone - Schizophrenia Patients, Auditory Hallucination | Not applicable | Completed | Hasanuddin University | 50 | 2025-11-01 | 2026-04-17 |
| MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study) 3,4-Methyl enedioxy methamphetamine, Methamphetamine, Cognitive Behavioral Therapy (CBT) - Obsessive-Compulsive Disorder | Phase 2 | Recruiting | Carolyn Rodriguez | 40 | 2025-09-10 | 2026-03-05 |
| Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer: A Randomized Clinical Trial Cognitive Behavioral Therapy (CBT), Education, Questionnaires - Childhood Cancer Survivor, Chronic Pain | Not applicable | Recruiting | St. Jude Children's Research Hospital | 116 | 2025-09-05 | 2026-09-03 |
| Comparative Efficacy of Cognitive Behavioral and Mindfulness Therapies in Reducing Post-Traumatic Stress Disorder Among Interpersonal Violence Survivors Cognitive Behavioral Therapy (CBT), Mindfulness-Based Therapy (MBT), Psychoeducation - Post-traumatic Stress Disorder (PTSD), Post-Traumatic Stress Disorder | Not applicable | Active not recruiting | GIFT University | 60 | 2025-08-27 | 2026-09-03 |
| Efficacy of Traditional Integrated Islamic Psychotherapy and Cognitive Behavioural Therapy for Migraine: A Randomized Controlled Trial Cognitive Behavioral Therapy (CBT), Traditional Integrated Islamic Psychotherapy (TIIP), Medication Group - Chronic Migraine Headache | Not applicable | Completed | GIFT University | 45 | 2025-03-10 | 2026-09-03 |
| Psychological Treatment for Paraphilic Disorders Cognitive behavioral therapy (CBT) - Paraphilic Disorders | Not applicable | Recruiting | Region Stockholm | 14 | 2025-03-04 | 2026-06-04 |
| RCT of Short-Term Psychoanalytic vs. Cognitive Behavioral Therapy for GAD Psychoanalytic Psychotherapy, Cognitive Behavioral Therapy (CBT) - Generalized Anxiety Disorder | Not applicable | Recruiting | Beykoz University | 60 | 2025-02-01 | 2025-02-18 |
| Fatigue Reduction in Chronic Kidney Disease (CKD) Cognitive Behavioral Therapy (CBT) - Chronic Kidney Diseases, Fatigue | Not applicable | Completed | NYU Langone Health | 5 | 2025-01-30 | 2025-12-18 |
| EEG Evaluation of CBT for Obsessive-Compulsive Disorder Cognitive Behavioral Therapy (CBT) - Obsessive-Compulsive Disorder | Not applicable | Active not recruiting | Uskudar University | 60 | 2025-01-01 | 2025-06-03 |
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Depression (35) · Anxiety Disorders (20) · Stress Disorders, Post-Traumatic (14) · Depressive Disorder, Major (9) · Generalized Anxiety Disorder (8) · Chronic Pain (7) · Obsessive-Compulsive Disorder (7) · Phobia, Social (6) · Schizophrenia (6) · Attention Deficit Disorder with Hyperactivity (5) · Substance-Related Disorders (5) · Binge-Eating Disorder (4) · Cocaine-Related Disorders (4) · Psychotic Disorders (4) · Bipolar Disorder (3)
Massachusetts General Hospital (8) · University of California, Los Angeles (5) · Karolinska Institutet (4) · University of Michigan (4) · Fred Hutchinson Cancer Center (3) · GIFT University (3) · Medical University of South Carolina (3) · NYU Langone Health (3) · Stanford University (3) · University of California, San Francisco (3) · University of Washington (3) · Dartmouth-Hitchcock Medical Center (2) · Duke University (2) · Emory University (2) · Icahn School of Medicine at Mount Sinai (2)
United States (93) · Sweden (6) · Netherlands (5) · Pakistan (5) · Turkey (Türkiye) (5) · Germany (3) · Canada (2) · China (2) · Egypt (2) · Australia (1) · Brazil (1) · Indonesia (1) · Italy (1) · Mexico (1) · Norway (1)
Ashley E Mason, PhD (3) · Denise E Wilfley, Ph.D. (2) · Frederick M Hecht, MD (2) · Mark P Jensen, Ph.D. (2) · Sabine Wilhelm, PhD (2) · Alice Kuo, MD, PhD (1) · Alicia E Meuret, PhD (1) · Amy Farabaugh, Ph.D. (1) · Andreas Bechdolf, Dr. (1) · Anna M Georgiopoulos, MD (1) · Anne Guhn, Dr. (1) · Arthur J. Barsky, MD (1)
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