4 completed, 1 active not recruiting. 5 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 4, Active not recruiting 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 1 | Completed 1 |
Follow Codeine: new trials by email Literature Review of Codeine trials Research Report on Codeine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure Carbidopa-Levodopa 25 Mg-100 Mg Oral Tablet, Naproxen 500 Mg, Opioids - Opioid Use, Opioid Dependence | Phase 2 | Active not recruiting | Northwestern University | 60 | 2021-01-01 | 2024-11-27 |
| E7 TCR T Cells for Human Papillomavirus-Associated Cancers E7 TCR cells, Aldesleukin, Fludarabine - Papillomavirus Infections, Cervical Intraepithelial Neoplasia | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 224 | 2017-01-27 | 2026-03-09 |
| Proof-of-concept Study to Assess the Efficacy, Tolerability and Safety of a Single Intraarticular Dose of GZ389988 Versus Placebo in Patients With Painful Osteoarthritis of the Knee placebo, GZ389988, acetaminophen or paracetamol - Osteoarthritis | Phase 2 | Completed | Genzyme, a Sanofi Company | 104 | 2016-07-21 | 2022-04-13 |
| Idiopathic Intracranial Hypertension Treatment Trial Acetazolamide, Placebo, Formal weight loss counselling program - Idiopathic Intracranial Hypertension | Phase 2 / Phase 3 | Completed | St. Luke's-Roosevelt Hospital Center | 165 | 2010-01-01 | 2018-12-12 |
| Codeine in Sickle Cell Disease Codeine (30 mg) - Sickle Cell Disease | Phase 1 / Phase 2 | Completed | PriCara, Unit of Ortho-McNeil, Inc. | 60 | 2005-03-01 | 2011-06-30 |
Pain (2) · Anemia, Sickle Cell (1) · Back Injuries (1) · Back Pain (1) · Carcinoma in Situ (1) · Chronic Pain (1) · Diplopia (1) · Headache (1) · Obesity (1) · Opioid-Related Disorders (1) · Osteoarthritis (1) · Papilledema (1) · Papillomavirus Infections (1) · Pseudotumor Cerebri (1) · Tinnitus (1)
Genzyme, a Sanofi Company (1) · National Cancer Institute (NCI) (1) · Northwestern University (1) · PriCara, Unit of Ortho-McNeil, Inc. (1) · St. Luke's-Roosevelt Hospital Center (1)
United States (4) · Canada (1) · Germany (1)
Apkar V Apkarian, PhD (1) · Michael Wall, MD (1) · Scott M Norberg, D.O. (1) · Stacy S. Shord, PharmD (1)
PMID 24756302, PMID 24756514, PMID 24781936, PMID 25370510, PMID 25370513, PMID 26024112, PMID 26335066, PMID 26618282, PMID 26778344, PMID 26934136, PMID 27694262, PMID 28130349, PMID 28492874, PMID 31351965, PMID 33558725
2014 (1), U10EY017281 (1), U10EY017387 (1)