8 completed, 3 recruiting, 2 unknown, 1 terminated. 14 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 14 | Completed 8, Recruiting 3, Unknown 2, Terminated 1 |
Follow Buspirone: new trials by email Literature Review of Buspirone trials Research Report on Buspirone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Buspirone for Anxiety in Autistic Youth buspirone, Placebo - Anxiety, Autism Spectrum Disorder | Phase 4 | Recruiting | Massachusetts General Hospital | 20 | 2026-09-01 | 2026-09-17 |
| Buspirone Treatment of Anxiety in Williams Syndrome Buspirone - Williams Syndrome, Anxiety | Phase 4 | Completed | Massachusetts General Hospital | 20 | 2021-08-01 | 2024-12-03 |
| Buspirone for Weak or Absent Esophageal Peristalsis Buspirone Hydrochloride 10 MG, Placebo - Dysphagia, Esophageal | Phase 4 | Unknown | Universitaire Ziekenhuizen KU Leuven | 25 | 2021-07-06 | 2024-07-03 |
| Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment Acetazolamide + supplemental oxygen + PAP therapy, Zolpidem + PAP therapy, Buspirone + PAP therapy - Sleep Disordered Breathing, Able Bodied | Phase 4 | Recruiting | VA Office of Research and Development | 200 | 2021-01-07 | 2026-07-20 |
| Buspirone and Melatonin for Depression Following Traumatic Brain Injury Buspirone, Mealatonin - Depression, Brain Injuries, Traumatic | Phase 4 | Recruiting | Massachusetts General Hospital | 10 | 2020-08-01 | 2026-05-06 |
| Improving Driving in Young People With Autism Spectrum Disorders Buspirone - Autism Spectrum Disorder | Phase 4 | Completed | Massachusetts General Hospital | 26 | 2018-10-31 | 2021-03-18 |
| Buspirone Plus Omeprazole for Functional Dyspepsia Buspirone, Placebo Oral Tablet - Dyspepsia | Phase 4 | Completed | Isfahan University of Medical Sciences | 70 | 2016-03-01 | 2018-02-23 |
| Mechanistic Investigation Of Intestinal Cytochrome p450 3A4 Following Roux-en-Y Surgery And Its Effect on Plasma Concentrations of Buspirone Buspirone, Buspirone and Grapefruit Juice - Gastric Bypass | Phase 4 | Terminated | North Dakota State University | 12 | 2015-06-01 | 2018-08-24 |
| Randomized，Controlled and Open-label Study of Buspirone add-on Treatment in Patients With Major Depression Disorder Buspirone, Paroxetine - Major Depression Disorder | Phase 4 | Unknown | Si Tianmei | 240 | 2014-08-01 | 2014-10-23 |
| Buspirone for the Treatment of Traumatic Brain Injury (TBI) Irritability and Aggression Buspirone, Placebo - Traumatic Brain Injury | Phase 4 | Completed | Indiana University | 81 | 2013-05-15 | 2026-02-24 |
| Buspirone Treatment for Marijuana Dependence Buspirone, Placebo - Marijuana Dependence | Phase 4 | Completed | Medical University of South Carolina | 175 | 2009-09-01 | 2016-08-10 |
| Dexmed/Buspirone Synergism on Shivering dexmedetomidine, buspirone, Bus and Dex - Hypothermia | Phase 4 | Completed | The Cleveland Clinic | 8 | 2004-09-01 | 2016-06-29 |
| Effects of Buspirone in Opiate Withdrawal Buspirone - Heroin Dependence | Phase 4 | Completed | National Institute on Drug Abuse (NIDA) | 2002-01-01 | 2017-01-12 | |
| Sequenced Treatment Alternatives to Relieve Depression (STAR*D) citalopram, BuproprionSR, buspirone - Depression | Phase 4 | Completed | National Institute of Mental Health (NIMH) | 4000 | 2001-07-01 | 2009-09-25 |
Anxiety Disorders (4) · Autism Spectrum Disorder (2) · Brain Injuries, Traumatic (2) · Depression (2) · Depressive Disorder, Major (2) · Aggression (1) · Autistic Disorder (1) · Behavior (1) · Deglutition Disorders (1) · Depressive Disorder, Treatment-Resistant (1) · Dyspepsia (1) · Heroin Dependence (1) · Hypothermia (1) · Marijuana Abuse (1) · Sleep Apnea Syndromes (1)
Massachusetts General Hospital (4) · Indiana University (1) · Isfahan University of Medical Sciences (1) · Medical University of South Carolina (1) · National Institute of Mental Health (NIMH) (1) · National Institute on Drug Abuse (NIDA) (1) · North Dakota State University (1) · Si Tianmei (1) · The Cleveland Clinic (1) · Universitaire Ziekenhuizen KU Leuven (1) · VA Office of Research and Development (1)
United States (10) · Belgium (1) · China (1)
A. John Rush, MD (1) · Aimee McRae-Clark, Pharm.D. (1) · Flora Hammond, MD (1) · Jan Tack (1) · Laure Buydens-Branchey, M.D. (1) · M Safwan Badr, MD (1) · Rainer Lenhardt, MD, PhD (1) · Robyn P Thom, MD (1)
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I01CX001944 (1), R01DA026782 (1)