13 completed, 6 unknown, 2 withdrawn, 1 not yet recruiting. 24 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 24 | Completed 13, Unknown 6, Withdrawn 2, Not yet recruiting 1, Recruiting 1, Terminated 1 |
Follow Acetaminophen: new trials by email Literature Review of Acetaminophen trials Research Report on Acetaminophen
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison Of Acetaminophen, NSAIDs, And Trypsin-Chymotrypsin Plus Acetaminophen For Post-Endodontic Pain After Single-Visit Root Canal Treatment Acetaminophen, NSAID, trypsin-chymotrypsin - Symptomatic Irreversible Pulpitis (SIP) | Early Phase 1 | Recruiting | Dow University of Health Sciences | 90 | 2026-08-02 | 2026-08-19 |
| Quadro-Iliac Plane Block for Pain Control After Posterior Spinal Instrumentation Surgery Fentanyl (IV), Meperidine, Paracetamol (acetaminophen) - Posterior Spinal Instrumentation Patients | Early Phase 1 | Not yet recruiting | Istanbul Medipol University Hospital | 60 | 2026-08-01 | 2026-08-28 |
| Paracetamol Plus Tramadol Versus Fentanyl As Preemptive Analgesia For Enhanced Recovery After Day Case Surgeries tramadol plus paracetamol, Fentanyl, propofol and muscle relaxant (cisatracurium) - Preemptive Paracetamol Plus Tramadol and Preemptive Fentanyl | Early Phase 1 | Unknown | Zagazig University | 102 | 2024-09-01 | 2024-08-20 |
| Pain Control Following Third Molar Surgery Paracetamol and Ibuprofen. The combination of the Paracetamol and Ibuprofen will be given together every 8 hours, Paracetamol and Ibuprofen. The combination of the Paracetamol and Ibuprofen will be given alternatively every four hours - Post Operative Pain, Impacted Third Molar Tooth | Early Phase 1 | Unknown | University of Sharjah | 56 | 2024-07-01 | 2024-07-23 |
| Pain Relief After Corneal Collagen Cross-Linking Gabapentin, Targin, NSAID - Provide Evidence-based Recommendations for Clinicians to Optimize Pain Control After CXL | Early Phase 1 | Unknown | Assaf-Harofeh Medical Center | 51 | 2024-02-01 | 2024-01-19 |
| Posterior Tibia Nerve Neuroprolotherapy for Dysmenorrhea Posterior tibial nerve neuroprolotherapy, Acetaminophen 500Mg Tab - Dysmenorrhea, Prolotherapy | Early Phase 1 | Unknown | Taichung Armed Forces General Hospital | 60 | 2023-11-23 | 2024-03-06 |
| Melphalan on Disease Burden Measured by Next Generation Sequencing Before AHCT (Autologous Hematopoietic Cell Transplant) for Multiple Myeloma Evomela, Next Generation Sequencing, Prochlorperazine - Multiple Myeloma | Early Phase 1 | Withdrawn | Koen van Besien | 2023-09-01 | 2024-04-02 | |
| Fentanyl vs Dexmedetomidine for Arthriscopic Shoulder Intervention in Elderly. Dexmedetomidine - Shoulder Lesions | Early Phase 1 | Completed | Cairo University | 36 | 2022-09-03 | 2022-11-21 |
| Prevention of Post-Operative Shivering paracetamol, ondansetron, normal saline - Post-Operative Shivering | Early Phase 1 | Completed | Cairo University | 120 | 2021-01-06 | 2022-03-31 |
| Towards Enhanced Recovery After Cesarean Ibuprofen, acetaminophen, oxycodone - Cesarean Section Complications | Early Phase 1 | Completed | University of Oklahoma | 33 | 2020-12-12 | 2023-03-14 |
| Multimodal Opioid-free Anesthesia Versus Opioid-based Anesthesia for Patients Undergoing Cardiac Valve Surgeries: RCT Dexmedetomidine 0.5 mic/kg/h, Fentanyl 1 mic/kg/hr - Anesthesia | Early Phase 1 | Completed | Cairo University | 60 | 2020-12-01 | 2023-08-30 |
| Pain Management Following Sinus Surgery Ibuprofen 600Mg Tablet, Standard Regimen | Tylenol - Nasal Sinus; Inflammation, Opioid Abuse | Early Phase 1 | Terminated | University of Nebraska | 10 | 2020-11-07 | 2023-09-06 |
| Impact of Acetaminophen on Postoperative Delirium Elderly Patients After Non-cardiac Surgery Acetaminophen, Sufentanil - Acetaminophen, Delirium in Old Age | Early Phase 1 | Unknown | Xiangya Hospital of Central South University | 164 | 2019-02-15 | 2019-03-08 |
| Nonopioid Analgesia After Arthroscopic Meniscus Surgery Celecoxib, Hydrocodon/Acetaminophen, Ketorolac - Meniscus Disorder, Narcotic Use | Early Phase 1 | Completed | Henry Ford Health System | 61 | 2019-01-22 | 2023-12-05 |
| 4-methylpyrazole and Acetaminophen Metabolism Fomepizole, APAP - Healthy Adult Volunteers | Early Phase 1 | Completed | University of Arizona | 6 | 2018-07-01 | 2019-09-26 |
| Controlled Trial to Determine Most Effective Post-Operative Analgesia After Third Molar Extraction Ketorolac, Oxycodone, Acetaminophen - Pain, Post-operative, Third Molar | Early Phase 1 | Completed | United States Naval Medical Center, San Diego | 80 | 2018-02-14 | 2024-07-10 |
| Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery IV acetaminophen, Fentanyl, PO acetaminophen - Emergence Agitation, Pain | Early Phase 1 | Completed | Nemours Children's Clinic | 143 | 2017-10-03 | 2020-01-18 |
| A Cohort Study Evaluating the Efficacy of PO Magnesium in the Treatment of Acute Traumatic Brain Injury in Adolescents Magnesium Oxide, Acetaminophen, Zofran ODT 4 MG Disintegrating Oral Tablet - Concussion Post Syndrome | Early Phase 1 | Completed | Corewell Health South | 17 | 2017-09-01 | 2024-11-29 |
| Acupuncture for Pain in the Emergency Department Auricular Acupuncture, Acupuncture, Placebo Acupuncture - Musculoskeletal Pain, Pain | Early Phase 1 | Withdrawn | Loma Linda University | 2017-07-27 | 2017-07-28 | |
| The Effect of Timing of Intravenous Paracetamol Administration on Post-surgical Pain IV paracetamol, IV saline (NaCl 0.9 %) - Obesity, Morbid | Early Phase 1 | Unknown | Soroka University Medical Center | 126 | 2017-07-01 | 2017-07-25 |
Showing 20 of 24. Sign in to see all of them.
Pain, Postoperative (4) · Agnosia (2) · Pain (2) · Acute Pain (1) · Delirium (1) · Dysmenorrhea (1) · Emergence Delirium (1) · Glaucoma (1) · Multiple Myeloma (1) · Musculoskeletal Pain (1) · Obesity, Morbid (1) · Opioid-Related Disorders (1) · Post-Concussion Syndrome (1) · Postoperative Hemorrhage (1) · Sinusitis (1)
Cairo University (3) · Johns Hopkins University (2) · Assaf-Harofeh Medical Center (1) · Corewell Health South (1) · Dow University of Health Sciences (1) · Hadassah Medical Organization (1) · Henry Ford Health System (1) · Istanbul Medipol University Hospital (1) · Koen van Besien (1) · Loma Linda University (1) · Nemours Children's Clinic (1) · Soroka University Medical Center (1) · Sun Yat-sen University (1) · Taichung Armed Forces General Hospital (1) · United States Naval Medical Center, San Diego (1)
United States (10) · Egypt (4) · Israel (2) · China (1) · Pakistan (1) · Taiwan (1) · Turkey (Türkiye) (1) · United Arab Emirates (1)
Alexander Zlotnic, PhdMD (1) · Carlos A Archilla, MD (1) · Christie Barnes, MD (1) · Christopher Trigger, MD, CAQSM (1) · Dalia K Ismail (1) · Henry D Jampel, MD (1) · Kamis Gaballah, PhD (1) · Koen van Besien, MD, PhD (1) · Michael Semionov, MD (1) · Patrick T Morrell, DMD (1) · Pavan Parikh, MD (1) · Richard L Skolasky, ScD (1) · Toufic R Jildeh, MD (1) · Traci Marin, PhD (1) · Yair Binyamin, MD (1)
PMID 11748392, PMID 19961114, PMID 20608558, PMID 21224800, PMID 21252836, PMID 21495003, PMID 21516915, PMID 21823370, PMID 22250276, PMID 22833138, PMID 23011043, PMID 23054575, PMID 25723660, PMID 31768936, PMID 39656149, PMID 40160919, PMID 40181005, PMID 41014734, PMID 42028138