26 completed, 3 unknown, 2 terminated, 1 recruiting. 14 Phase 2, 7 Phase 3, 5 Phase 1, 3 Not applicable, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 14 | Completed 12, Terminated 1, Unknown 1 |
| Phase 3 | 7 | Completed 6, Terminated 1 |
| Phase 1 | 5 | Completed 5 |
| Not applicable | 3 | Completed 2, Unknown 1 |
| Phase 4 | 2 | Completed 1, Terminated 1 |
Follow Wegener's Granulomatosis: new trials by email Literature Review of Wegener's Granulomatosis trials Research Report on Wegener's Granulomatosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vasculitis Pregnancy Registry Online questionnaires - Vasculitis, Behcet's Disease | Recruiting | University of Pennsylvania | 100 | 2015-11-01 | 2026-01-23 | |
| Abatacept for the Treatment of Relapsing, Non-Severe, Granulomatosis With Polyangiitis (Wegener's) Abatacept, placebo - Granulomatosis With Polyangiitis (Wegener's), Granulomatosis With Polyangiitis | Phase 3 | Completed | University of South Florida | 65 | 2015-04-25 | 2024-07-29 |
| Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases Interleukin 2 - Rheumatoid Arthritis, Ankylosing Spondylitis | Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 81 | 2014-01-06 | 2021-07-20 |
| Reproductive Health in Men and Women With Vasculitis Giant Cell Arteritis, Takayasu's Arteritis | Completed | University of South Florida | 467 | 2011-02-01 | 2014-06-26 | |
| American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) Diagnostic and Classification Criteria for Primary Systemic Vasculitis Wegener's Granulomatosis, Microscopic Polyangiitis | Unknown | University of Oxford | 3588 | 2011-01-01 | 2016-08-19 | |
| Study of One Protein Implicated in Wegener Disease Physiopathology Endpoint Classification - Wegener's Granulomatosis | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 138 | 2010-05-01 | 2026-03-31 |
| Interventional Cryotherapy for the Eradication of Benign Airway Disease ("ICE the BAD") CryoSpray Ablation - Lung Diseases, Obstructive, Sarcoidosis | Phase 4 | Terminated | CSA Medical, Inc. | 5 | 2008-10-01 | 2015-08-18 |
| Abatacept in Treating Adults With Mild Relapsing Wegener's Granulomatosis Abatacept - Wegener's Granulomatosis | Phase 1 / Phase 2 | Completed | University of Pennsylvania | 20 | 2008-02-01 | 2016-01-18 |
| Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years prednisone, methylprednisolone,cyclophosphamides, Cyclophosphamide, Azathioprine,prednisone,methylprednisolone, Mycophenolate mofetil,methotrexate - Vasculitis, Wegener's Granulomatosis | Phase 4 | Completed | Assistance Publique - Hôpitaux de Paris | 108 | 2005-07-01 | 2011-09-12 |
| Rituximab for the Treatment of Wegener's Granulomatosis and Microscopic Polyangiitis Rituximab plus cyclophosphamide placebo (rituximab group), Cyclophosphamide plus rituximab placebo (control group), Azathioprine - Vasculitis, Wegener's Granulomatosis | Phase 2 / Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 197 | 2005-01-01 | 2017-04-21 |
| Mycophenolate Mofetil for Treatment of Relapses of Wegener's Disease or Microscopic Polyangiitis (MPA) mycophenolate mofetil, cyclophosphamide - Wegener's Granulomatosis, Vasculitis | Phase 3 | Completed | University Medical Center Groningen | 84 | 2004-12-01 | 2024-08-27 |
| RATTRAP: Infliximab Versus Rituximab in Systemic Necrotizing Vasculitides Infliximab, Rituximab - Wegener's Granulomatosis, Churg-Strauss Syndrome | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 20 | 2004-05-01 | 2007-11-19 |
| Phase II Study on Gusperimus in Patients With Refractory Wegener's Granulomatosis Gusperimus - Wegener's Granulomatosis | Phase 2 | Completed | Nippon Kayaku Co., Ltd. | 45 | 2003-12-01 | 2017-03-06 |
| An Open Label Pilot Study Examining the Use of Rituximab in Patients With Wegener's Granulomatosis Who Have Experienced Disease Relapse on Standard Therapies Rituximab - Wegener's Granulomatosis | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 10 | 2003-10-01 | 2008-03-04 |
| Anti-Cytokine Therapy for Vasculitis Infliximab, Cyclophosphamide, Prednisolone - Wegener's Granulomatosis, Renal Limited Vasculitis | Phase 2 | Completed | University Hospital Birmingham NHS Foundation Trust | 37 | 2003-01-01 | 2008-09-16 |
| Daclizumab to Treat Wegener's Granulomatosis Daclizumab - Wegener's Granulomatosis | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 75 | 2002-06-01 | 2008-03-04 |
| Etanercept for Wegener's Granulomatosis Etanercept - Wegener's Granulomatosis | Phase 2 / Phase 3 | Completed | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 181 | 2000-06-01 | 2007-12-28 |
| Prevention of Glucocorticoid-Induced Osteoporosis in Rheumatic Diseases: Alendronate Versus Alfacalcidol. Alendronate versus alfacalcidol (1-alpha OH vitamin D) - Rheumatoid Arthritis, Polymyalgia Rheumatica | Phase 3 | Completed | UMC Utrecht | 200 | 2000-05-01 | 2006-11-29 |
| Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases anti-thymocyte globulin, cyclophosphamide, cyclosporine - Purpura, Schoenlein-Henoch, Graft Versus Host Disease | Not applicable | Unknown | Fairview University Medical Center | 10 | 2000-03-01 | 2005-06-24 |
| Comparison of Treatments to Maintain Disease Remission in Patients With Wegener's Granulomatosis and Related Vasculitis Syndromes Mycophenolate Mofetil - Vasculitis, Wegener's Granulomatosis | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 75 | 2000-02-01 | 2008-03-04 |
Showing 20 of 32. Sign in to see all of them.
Granulomatosis with Polyangiitis (32) · Vasculitis (22) · Microscopic Polyangiitis (11) · Churg-Strauss Syndrome (7) · Polyarteritis Nodosa (6) · Recurrence (5) · Giant Cell Arteritis (4) · Inflammation (4) · Takayasu Arteritis (4) · Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (3) · Arthritis, Rheumatoid (3) · Behcet Syndrome (3) · IgA Vasculitis (3) · Systemic Vasculitis (3) · Lung Diseases (2)
Cardiovascular Diseases (32) · Lung Diseases, Interstitial (32) · Skin Diseases (32) · Skin Diseases, Vascular (32) · Skin and Connective Tissue Diseases (32) · Autoimmune Diseases (31) · Immune System Diseases (31) · Lung Diseases (30) · Respiratory Tract Diseases (30) · Vascular Diseases (30) · Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (29) · Systemic Vasculitis (29) · Pathologic Processes (14) · Pathological Conditions, Signs and Symptoms (14) · Brain Diseases (13)
Cyclophosphamide (8) · Mycophenolic Acid (5) · Methylprednisolone (4) · Prednisone (4) · Azathioprine (3) · Methotrexate (3) · Rituximab (3) · Abatacept (2) · Etanercept (2) · Infliximab (2) · Plasma Exchange (2) · Antilymphocyte Serum (1) · Control Groups (1) · Cryoelectron Microscopy (1) · Cryosurgery (1)
National Institute of Allergy and Infectious Diseases (NIAID) (12) · Assistance Publique - Hôpitaux de Paris (4) · Cambridge University Hospitals NHS Foundation Trust (2) · University of Pennsylvania (2) · University of South Florida (2) · CSA Medical, Inc. (1) · Fairview University Medical Center (1) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (1) · National Institutes of Health Clinical Center (CC) (1) · Nippon Kayaku Co., Ltd. (1) · UMC Utrecht (1) · University Hospital Birmingham NHS Foundation Trust (1) · University Medical Center Groningen (1) · University of Oxford (1) · University of Parma (1)
United States (21) · France (5) · Netherlands (5) · United Kingdom (5) · Germany (3) · Canada (2) · Czechia (2) · Denmark (2) · Ireland (2) · Italy (2) · Sweden (2) · Argentina (1) · Australia (1) · Austria (1) · Belgium (1)
John H. Stone, MD, MPH (2) · Megan Clowse, MD, MPH (2) · Peter A Merkel, MD, MPH (2) · Amanda M. Terry, MA (1) · Arne Slungaard (1) · Carlo Buzio, MD (1) · Carol A Langford, MD, MHS (1) · Carol A. Langford, MD, MHS (1) · Caroline OS Savage (1) · Coen Stegeman, MD PhD (1) · David Jayne (1) · Jeffrey P Krischer, PhD (1) · Kirsten de Groot (1)
PMID 12905485, PMID 15751091, PMID 15838068, PMID 15986348, PMID 16378799, PMID 16646004, PMID 16914703, PMID 17407214, PMID 17557758, PMID 19451574, PMID 20647199, PMID 22127969, PMID 22975753, PMID 23615499, PMID 23754238, PMID 23902481, PMID 24323392, PMID 25047592, PMID 25693055, PMID 25776953, PMID 26387933, PMID 26621483, PMID 27696762, PMID 27940595, PMID 28592297, PMID 29016646, PMID 30472651, PMID 31216123, PMID 33367837, PMID 34618687, PMID 38825350, PMID 38825354
U54AR057319 (2)