19 completed, 14 recruiting, 12 unknown, 4 active not recruiting. 26 Not applicable, 14 Phase 2, 4 Phase 1, 2 Early Phase 1, 2 Phase 3.
Follow Vestibular Schwannoma: new trials by email Literature Review of Vestibular Schwannoma trials Research Report on Vestibular Schwannoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Role of ChatGPT in Vestibular Schwannoma Management Use of chatGPT for 1 week - Vestibular Schwannoma | Not applicable | Withdrawn | University of Southern California | 2027-01-01 | 2026-01-13 | |
| Luvometinib in Combination With Serplulimab for NF2-Related Tumors Luvometinib, Serplulimab - NF2-related Schwannomatosis, NF2 | Phase 1 / Phase 2 | Not yet recruiting | Beijing Tiantan Hospital | 30 | 2026-07-31 | 2026-07-16 |
| Platform Research for Innovative Medicines in NF2-SWN (PRIME-NF2) Selumetinib 25mg/m2, Luvometinib, Serplulimab - Neurofibromatosis Type 2, Vestibular Schwannoma | Phase 2 | Not yet recruiting | Beijing Tiantan Hospital | 200 | 2026-07-18 | 2026-07-20 |
| Selumetinib for NF2-Related Schwannomatosis Selumetinib - Neurofibromatosis Type 2, NF2 | Phase 2 | Not yet recruiting | Beijing Tiantan Hospital | 20 | 2026-07-15 | 2026-07-16 |
| Measuring Vestibular Organ Function With Weak Alternating Current Stimulation Active transcranial electrical vestibular stimulation (Active EVS), Sham transcranial electrical vestibular stimulation (Sham EVS), Control measurement - Vestibular Disorder, Vestibular Schwannoma | Not applicable | Enrolling by invitation | Aalto University | 30 | 2026-06-08 | 2026-07-01 |
| Long Term Follow-up Study of AAVAnc80-antiVEGF Gene Therapy Vestibular Schwannoma | Enrolling by invitation | Akouos, Inc. | 100 | 2026-03-02 | 2026-07-16 | |
| Steroids for Facial Nerve Function Protection in Post-surgical Vestibular Schwannoma Patients Steroids therapy, Placebo - Vestibular Schwannoma, Facial Nerve Paralysis | Phase 3 | Recruiting | Beijing Tiantan Hospital | 364 | 2025-10-09 | 2026-10-26 |
| 3D MRE-Based Evaluation of Vestibular Schwannoma Mechanical Properties and Histological Features Vestibular Schwannoma | Recruiting | Shengjing Hospital | 30 | 2025-09-25 | 2026-10-16 | |
| Vestibular Rehabilitation Protocol in Unilateral Vestibular Schwannoma No Intervention: Observational Cohort, Structured home-based vestibular telerehabilitation program, CE-marked clinical rotatory chair - Vestibular Schwannoma, Vestibular Schwannomas | Not applicable | Recruiting | Albert Torrents Torrero | 75 | 2025-09-01 | 2026-01-23 |
| Mapping of Vestibular Centers Activation Using fMRI in Patients With Vestibular Schwannoma vestibular schwannoma resection - Vestibular Schwannoma, Unilateral Vestibular Deficit | Not applicable | Recruiting | Marketa Bonaventurova | 40 | 2025-06-01 | 2026-10-22 |
| Early Rehabilitation Using Head Impulse Test for Acute Vestibular Deficit Experimental treatment: Head movements, Sham treatment: only eye movements - Vestibular Schwannoma, Unilateral Vestibular Deficit | Not applicable | Recruiting | Hospices Civils de Lyon | 26 | 2025-05-13 | 2025-05-16 |
| Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma AAVAnc80-antiVEGF via Akouos Delivery Device - Vestibular Schwannoma | Phase 1 / Phase 2 | Recruiting | Akouos, Inc. | 27 | 2025-01-17 | 2026-04-06 |
| USPIO Enhanced MR Imaging in CNS Tumours (UMIC) USPIO enhanced MRI - Vestibular Schwannoma, Glioma, Astrocytic | Not applicable | Recruiting | Northern Care Alliance NHS Foundation Trust | 17 | 2024-04-26 | 2024-08-27 |
| Evolution of Vestibular Function After Treatment of a Vestibular Schwannoma by Gamma-knife Radio-surgery Vestibular exam - Vestibular Schwannoma, Neurinoma, Acoustic | Not applicable | Unknown | Centre Hospitalier Universitaire de Besancon | 20 | 2024-02-20 | 2024-09-19 |
| Evaluating Pre-Treatment Vestibular Physical Therapy Rehab for Patients With Vestibular Schwannomas Microsurgical resection of VS, Stereotactic radiosurgery, PREHAB - Vestibular Schwannoma | Not applicable | Recruiting | Medical College of Wisconsin | 36 | 2024-01-22 | 2026-03-24 |
| Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular Schwannoma Stereotactic radiosurgery - Vestibular Schwannoma, Ototoxicity | Recruiting | University Hospital, Geneva | 258 | 2023-01-24 | 2025-01-13 | |
| Remote Ischemic Preconditioning in Vestibular Schwannoma Surgery Remote ischemic preconditioning, Sham-control - Vestibular Schwannoma | Not applicable | Unknown | University Hospital Tuebingen | 120 | 2022-10-01 | 2022-10-05 |
| StableEyes With Active Neurofeedback Traditional Therapy, SWAN - Vestibular Disorder, Vestibular Schwannoma | Not applicable | Recruiting | Johns Hopkins University | 48 | 2022-08-08 | 2026-09-08 |
| Enhancing Facial Nerve Function With Omega-3 After Resection of Vestibular Schwannoma Omega-3, Placebo - Vestibular Schwannoma | Not applicable | Terminated | Mayo Clinic | 15 | 2021-11-01 | 2023-09-08 |
| Microscopic Fluorescence-guided Vestibular Schwannoma Resection Using Fluorescein Sodium and YELLOW 560 Fluorescein Sodium, YELLOW560 filter - Vestibular Schwannoma | Phase 2 | Completed | Mayo Clinic | 12 | 2021-10-06 | 2023-08-01 |
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Neuroma, Acoustic (63) · Neurofibromatosis 2 (14) · Meningioma (6) · Vestibular Diseases (6) · Hearing Loss (5) · Neurilemmoma (5) · Ependymoma (4) · Brain Neoplasms (3) · Dizziness (3) · Motion Sickness (2) · Vestibular Neuronitis (2) · Astrocytoma (1) · Bell Palsy (1) · Brain Stem Neoplasms (1) · Endolymphatic Hydrops (1)
Cranial Nerve Diseases (63) · Cranial Nerve Neoplasms (63) · Ear Diseases (63) · Neoplasms (63) · Neoplasms by Histologic Type (63) · Neoplasms by Site (63) · Neoplasms, Germ Cell and Embryonal (63) · Neoplasms, Nerve Tissue (63) · Nerve Sheath Neoplasms (63) · Nervous System Diseases (63) · Nervous System Neoplasms (63) · Neuroectodermal Tumors (63) · Neuroendocrine Tumors (63) · Otorhinolaryngologic Neoplasms (63) · Peripheral Nervous System Neoplasms (63)
Radiosurgery (4) · AZD 6244 (3) · Bevacizumab (3) · Gentamicins (3) · Cochlear Implants (2) · Lapatinib (2) · Aspirin (1) · Docosahexaenoic Acids (1) · Endostatins (1) · Exome (1) · Fluorescein (1) · Fluoresceins (1) · HDAC-42 (1) · Head Movements (1) · Losartan (1)
Beijing Tiantan Hospital (5) · Massachusetts Eye and Ear Infirmary (4) · Medical University of Vienna (3) · University Hospital Tuebingen (3) · Akouos, Inc. (2) · Assistance Publique Hopitaux De Marseille (2) · Central Hospital, Nancy, France (2) · Christoph Arnoldner (2) · Haukeland University Hospital (2) · Lund University (2) · Mayo Clinic (2) · Aalto University (1) · Albert Torrents Torrero (1) · Centre Hospitalier Universitaire de Besancon (1) · Charles University, Czech Republic (1)
United States (22) · France (8) · China (7) · Austria (5) · Germany (3) · Sweden (3) · United Kingdom (3) · Czechia (2) · Norway (2) · Finland (1) · Netherlands (1) · Spain (1) · Switzerland (1)
Aaron Tward, MD (2) · Fu Zhao (2) · Matthew L Carlson, MD (2) · Pinan Liu (2) · Anhua Wu, MD (1) · Brad Welling, MD, PhD (1) · Cameron C Wick, MD (1) · Christoph Arnoldner (1) · Christoph Arnoldner, MD (1) · Contantin Roder, Prof., MD (1) · D. Bradley Welling, MD, PhD (1)
PMID 17917842, PMID 19574236, PMID 19645909, PMID 22027076, PMID 11587600, PMID 11710496, PMID 11981398, PMID 12925338, PMID 14724495, PMID 15354006, PMID 17438254, PMID 18607963, PMID 19645932, PMID 20802221, PMID 26247776, PMID 26943915, PMID 26976425, PMID 28053986, PMID 31796939, PMID 33737417, PMID 34667843, PMID 35229827, PMID 36240730, PMID 36809199, PMID 37526718, PMID 38669501, PMID 38904277, PMID 39284021, PMID 41925729, PMID 42267547, PMID 9831156
P30CA006973 (1), R01DC003196 (1), R01DC017425 (1)