3 completed, 1 not yet recruiting, 1 recruiting, 1 suspended. 3 Not applicable, 2 Early Phase 1, 2 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 1, Recruiting 1, Withdrawn 1 |
| Early Phase 1 | 2 | Completed 1, Not yet recruiting 1 |
| Phase 4 | 2 | Suspended 1, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow Fluoresceins: new trials by email Literature Review of Fluoresceins trials Research Report on Fluoresceins
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| In Vivo Imaging of the Olfactory Epithelium Using Confocal Laser Endomicroscopy CONVIVO system, Fluorescein injection, USP 10% - Endonasal Surgery, Endoscopic Sinus Surgery | Early Phase 1 | Not yet recruiting | Dartmouth-Hitchcock Medical Center | 36 | 2026-11-03 | 2026-10-20 |
| Microscopic Fluorescence-guided Vestibular Schwannoma Resection Using Fluorescein Sodium and YELLOW 560 Fluorescein Sodium, YELLOW560 filter - Vestibular Schwannoma | Phase 2 | Completed | Mayo Clinic | 12 | 2021-10-06 | 2023-08-01 |
| Intravital Microscopy in Human Solid Tumors Diagnostic Microscopy, Fluorescein Sodium Injection - Solid Tumor, Adult, Clinical Stage IV Gastric Cancer AJCC v8 | Not applicable | Recruiting | Mayo Clinic | 85 | 2019-02-28 | 2026-06-02 |
| Fluorescein Angiography With a Full-dose Versus a Half-dose of Intravenous Fluorescein Fluorescein Na 10% Inj 500mg, Fluorescein Na 10% Inj 250mg - Fluorescein Angiography | Phase 4 | Suspended | Kresge Eye Institute | 79 | 2018-04-05 | 2020-03-16 |
| Intravital Microscopy in Evaluating Patients With Primary Peritoneal, Fallopian Tube, or Stage IA-IV Ovarian Cancer Diagnostic Microscopy, Fluorescein Sodium Injection, Laboratory Biomarker Analysis - Fallopian Tube Carcinoma, Primary Peritoneal Carcinoma | Early Phase 1 | Completed | Roswell Park Cancer Institute | 19 | 2017-11-06 | 2021-10-06 |
| Intravital Microscopy in Identifying Tumor Vessels in Patients With Stage IB-IIIC Melanoma Undergoing Sentinel Lymph Node Biopsy Diagnostic Microscopy, Fluorescein Sodium Injection, Laboratory Biomarker Analysis - Stage IB Skin Melanoma, Stage IIA Skin Melanoma | Not applicable | Completed | Roswell Park Cancer Institute | 20 | 2016-11-03 | 2022-08-01 |
| Confocal Laser Microlaryngoscopy (CLMx) Fluorescein injection, USP 10%, Confocal laser microlaryngoscopy, Biopsy (standard of care) - Laryngeal Dysplasia, Laryngeal Neoplasm | Not applicable | Withdrawn | Washington University School of Medicine | 2015-04-01 | 2016-09-09 | |
| Yellow 560 Microscope for Intraoperative Visualization of Fluorescein Stained Intracranial Lesions Fluorescein Sodium - Adult Intracranial Neoplasm, Vascular: Intracranial | Phase 4 | Terminated | Indiana University | 136 | 2013-12-01 | 2016-11-08 |
Brain Neoplasms (2) · Anosmia (1) · Breast Neoplasms (1) · Carcinoma, Hepatocellular (1) · Cholangiocarcinoma (1) · Colorectal Neoplasms (1) · Fallopian Tube Neoplasms (1) · Laryngeal Neoplasms (1) · Melanoma (1) · Neuroma, Acoustic (1) · Ovarian Neoplasms (1) · Pancreatic Neoplasms (1) · Sarcoma (1) · Stomach Neoplasms (1)
Mayo Clinic (2) · Roswell Park Cancer Institute (2) · Dartmouth-Hitchcock Medical Center (1) · Indiana University (1) · Kresge Eye Institute (1) · Washington University School of Medicine (1)
United States (7)
Aaron A Cohen, MD, MSc (1) · Emese Zsiros, MD (1) · Emmanuel M Gabriel, M.D., Ph.D. (1) · Gary W Abrams, MD (1) · Joseph Bradley, M.D. (1) · Joseph Skitzki (1) · Matthew L Carlson, MD (1)
PMID 12001988, PMID 17704903, PMID 19906081, PMID 19917863, PMID 20061178, PMID 20233873, PMID 20336386, PMID 20374484, PMID 20490982, PMID 20737573, PMID 21153378, PMID 21909917, PMID 21926464, PMID 22162570, PMID 23456602, PMID 24956510, PMID 25013744, PMID 26883450, PMID 2801858, PMID 33654117, PMID 36240730, PMID 37124504, PMID 3808620
UM1TR004772 (1)