14 completed. 14 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Completed 14 |
| Phase 2 | 1 | Completed 1 |
Follow Venous Insufficiency: new trials by email Literature Review of Venous Insufficiency trials Research Report on Venous Insufficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Resolution Enhancement by a Supplemental Obstruction Lessening Venoactive Drug for Eight Weeks in Deep Vein Thrombosis Hydroxyethylrutoside - Deep Vein Thrombosis | Phase 3 | Completed | Maastricht University Medical Center | 44 | 2020-12-08 | 2024-03-01 |
| Study Investigating the Safety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers >12 cm2 to ≤ 36 cm2 HP802-247, Vehicle - Venous Leg Ulcers | Phase 3 | Completed | Healthpoint | 155 | 2012-11-01 | 2017-07-26 |
| Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis Recombinant tissue plasminogen activator (rt-PA) - Deep Vein Thrombosis, Venous Thrombosis | Phase 3 | Completed | Washington University School of Medicine | 692 | 2009-11-01 | 2018-03-29 |
| Assess the Efficacy and Tolerability of Antistax Film-coated Tablets in Patients With Chronic Venous Insufficiency Red vine leaf extract (AS 195), Placebo - Venous Insufficiency | Phase 3 | Completed | Boehringer Ingelheim | 250 | 2009-03-01 | 2014-05-16 |
| THERMES ET VEINES: Spa for Prevention of Leg Ulcers Immediate spa treatment, Late spa treatment - Venous Insufficiency, Leg Ulcer | Phase 3 | Completed | Association Francaise pour la Recherche Thermale | 425 | 2008-05-01 | 2012-10-01 |
| Evaluation of the Duration of Therapy for Thrombosis in Children Shortened duration (6 weeks) of anticoagulant therapy, Conventional duration (3 months) of anticoagulant therapy, No Intervention - Venous Thrombosis | Phase 3 | Completed | Johns Hopkins All Children's Hospital | 532 | 2008-03-01 | 2025-06-18 |
| Efficacy and Tolerability CVI (A 12-week, Double-blind, Randomised, Placebo-controlled, Multicentre Trial (CVI) Read vine leaf extract (AS 195) - Venous Insufficiency | Phase 3 | Completed | Boehringer Ingelheim | 202 | 2006-03-01 | 2013-10-29 |
| The Influence of Compression Stockings on Skin's Barrier Function at Patients With Chronic Venous Disease urea contained compressing stockings, compressing stockings - Venous Insufficiency | Phase 2 / Phase 3 | Completed | University Medicine Greifswald | 42 | 2005-06-01 | 2005-09-20 |
| Clinical Study of BNS003 on Swelling in Legs Due to Venous Reflux BNS003 - Venous Insufficiency | Phase 3 | Completed | Boehringer Ingelheim | 180 | 2004-07-01 | 2014-08-08 |
| The SOX Trial: Compression Stockings to Prevent the Post-Thrombotic Syndrome Knee-length, graduated elastic compression stocking, Knee-length, placebo stocking - Deep Venous Thrombosis | Phase 3 | Completed | Sir Mortimer B. Davis - Jewish General Hospital | 806 | 2004-06-01 | 2014-08-18 |
| Evaluation of a Venous-Return Assist Device (Venowave) to Treat Post-Thrombotic Syndrome: A Randomized Controlled Trial Veno-device (Venowave) - Postphlebitic Syndrome | Phase 3 | Completed | Hamilton Health Sciences Corporation | 32 | 2004-05-01 | 2008-07-22 |
| Efficacy and Tolerability of Antistax® in Male and Female Patients Suffering From Chronic Venous Insufficiency Antistax®, Placebo - Venous Insufficiency | Phase 3 | Completed | Boehringer Ingelheim | 245 | 2004-04-01 | 2014-07-16 |
| ESGVS: Sclerotherapy With Lauromacrogol lauromacrogol - Venous Insufficiency, Saphenous Vein | Phase 3 | Completed | University Hospital, Grenoble | 150 | 2004-03-01 | 2006-07-06 |
| Evaluation of Long-Term Sequelae After Thrombophlebitis, i.e. Deep Venous Thrombosis of the Lower Extremities unfractionated heparin, Tinzaparin (Leo) - Deep Venous Thrombosis | Phase 3 | Completed | Aalborg University Hospital | 99 | 1993-10-01 | 2008-03-05 |
Postthrombotic Syndrome (6) · Venous Thrombosis (6) · Postphlebitic Syndrome (3) · Varicose Ulcer (2) · Venous Thromboembolism (2) · Leg Ulcer (1) · Thrombosis (1) · Ulcer (1) · Varicose Veins (1) · Wounds and Injuries (1)
Cardiovascular Diseases (14) · Vascular Diseases (14) · Embolism and Thrombosis (7) · Thrombosis (6) · Peripheral Vascular Diseases (3) · Phlebitis (3) · Skin Diseases (2) · Skin Ulcer (2) · Skin and Connective Tissue Diseases (2) · Thromboembolism (2) · Leg Ulcer (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1) · Varicose Veins (1)
AS 195 (2) · Antistax (1) · Heparin (1) · Hydroxyethylrutoside (1) · Polidocanol (1) · Tinzaparin (1) · Tissue Plasminogen Activator (1) · troxerutin (1)
Boehringer Ingelheim (4) · Aalborg University Hospital (1) · Association Francaise pour la Recherche Thermale (1) · Hamilton Health Sciences Corporation (1) · Healthpoint (1) · Johns Hopkins All Children's Hospital (1) · Maastricht University Medical Center (1) · Sir Mortimer B. Davis - Jewish General Hospital (1) · University Hospital, Grenoble (1) · University Medicine Greifswald (1) · Washington University School of Medicine (1)
Canada (4) · United States (4) · Germany (3) · Austria (2) · France (2) · Netherlands (2) · Australia (1) · Czechia (1) · Denmark (1) · Israel (1) · Puerto Rico (1)
Andrea Ladwig (1) · Benedicte Laursen, MD, DMSc (1) · Clive Kearon, MB, MRCP, FRCP(C), PhD (1) · Herbert B Slade, MD (1) · Martin O'Donnell, MB MRCPI (1) · Neil A Goldenberg, MD, PhD (1) · Robert Kirsner, MD (1) · Samuel Z Goldhaber, M.D. (1) · Suresh Vedantham, M.D. (1)
PMID 20047905, PMID 21239190, PMID 23537968, PMID 24135621, PMID 24315521, PMID 25183442, PMID 29037354, PMID 29211671, PMID 30586751, PMID 30699446, PMID 31354089, PMID 31592728, PMID 31843251, PMID 33141449, PMID 33445952, PMID 35015038, PMID 39321425, PMID 39968829
U01HL088476 (1), U01HL130048 (1)