4 completed, 1 withdrawn. 5 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 5 | Completed 4, Withdrawn 1 |
Follow Vasoconstriction: new trials by email Literature Review of Vasoconstriction trials Research Report on Vasoconstriction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sex Disparities in Hypoxic Sympatholysis and Impact of Obesity Cold Pressor Test - Obesity, Healthy | Early Phase 1 | Completed | University of Missouri-Columbia | 73 | 2020-12-09 | 2026-07-28 |
| Impact of Insulin on Sympathetic Nervous System-mediated Peripheral Vasoconstriction Insulin - Vasoconstriction, Healthy | Early Phase 1 | Completed | University of Missouri-Columbia | 28 | 2020-08-06 | 2023-02-17 |
| Role of Acetylcholine in Blood Flow Regulation in Healthy Adults: Effects of Age and Exercise Training Handgrip Exercise Training, Acetylcholine, Adenosine Triphosphate - Vasoconstriction, Vasodilation | Early Phase 1 | Withdrawn | Colorado State University | 2019-04-16 | 2021-08-02 | |
| Reflex Responses to Intermittent Hypoxia in Humans: Mechanisms and Consequences Hypoxic exposure, modified Oxford test, Oral Bosentan 62.5 mg - Sleep Apnea, Healthy | Early Phase 1 | Completed | University of Missouri-Columbia | 54 | 2016-12-20 | 2021-12-06 |
| Role of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3) Bosentan, Sitaxsentan, Placebo - Pulmonary Arterial Hypertension, Vasodilation | Early Phase 1 | Completed | University of Edinburgh | 10 | 2009-01-01 | 2015-07-21 |
Aneurysm (4) · Insulin Resistance (1) · Motor Activity (1) · Obesity (1) · Pulmonary Arterial Hypertension (1) · Sleep Apnea Syndromes (1)
Cardiovascular Diseases (4) · Vascular Diseases (4) · Nutritional and Metabolic Diseases (2) · Respiratory Tract Diseases (2) · Apnea (1) · Behavior (1) · Body Weight (1) · Dyssomnias (1) · Glucose Metabolism Disorders (1) · Hyperinsulinism (1) · Hypertension, Pulmonary (1) · Lung Diseases (1) · Metabolic Diseases (1) · Nervous System Diseases (1) · Nutrition Disorders (1)
Bosentan (2) · Acetylcholine (1) · Adenosine Triphosphate (1) · Atropine (1) · Endothelin-3 (1) · Insulin (1) · Nitroprusside (1) · Phenylephrine (1) · sitaxsentan (1)
University of Missouri-Columbia (3) · Colorado State University (1) · University of Edinburgh (1)
United States (4) · United Kingdom (1)
Frank Dinenno, PhD (1) · Jacqueline K Limberg, Ph.D. (1) · Jacqueline L Limberg, Ph.D. (1)
K99HL130339 (1), R00HL130339 (1)