16 completed, 4 unknown, 3 withdrawn, 1 not yet recruiting. 7 Not applicable, 5 Phase 2, 4 Phase 1, 3 Phase 3, 2 Early Phase 1.
Follow Adenosine Triphosphate: new trials by email Literature Review of Adenosine Triphosphate trials Research Report on Adenosine Triphosphate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of an ATP-Containing Parenteral Vitamin B Complex in Patients With Symptomatic Diabetic Polyneuropathy adenosine triphosphate, Vitamin B Complex - Neuropathic Pain | Phase 4 | Not yet recruiting | Egyptian International Pharmaceutical Industries Co | 200 | 2026-01-10 | 2025-12-22 |
| The Safety, Feasibility, and Repeatability of Inhaled ATP Cough Challenges Adenosine 5'-triphosphate - Chronic Cough (CC), Asthma | Phase 1 | Recruiting | McMaster University | 33 | 2025-08-05 | 2025-08-29 |
| Effectiveness of Audio-Tactile Performance Technique With Sing-Along Lyrics on Oral Hygiene Instruction to Visually Impaired Individuals ATP, ATP with song - Oral Hygiene, Visually Impaired Persons | Not applicable | Completed | Mahidol University | 40 | 2025-06-09 | 2026-06-23 |
| Rapid Improvement of Depression of Fluoxetine Combined With ATP Control group: Fluoxetine and Placebo, Experimental group: Fluoxetine and ATP, Control group: Fluoxetine and Phosphocreatine - Depression | Phase 2 | Unknown | Nanfang Hospital, Southern Medical University | 195 | 2020-01-07 | 2023-11-15 |
| Role of Acetylcholine in Blood Flow Regulation in Healthy Adults: Effects of Age and Exercise Training Handgrip Exercise Training, Acetylcholine, Adenosine Triphosphate - Vasoconstriction, Vasodilation | Early Phase 1 | Withdrawn | Colorado State University | 2019-04-16 | 2021-08-02 | |
| Functional Magnetic Resonance Imaging of ATP Cough in Chronic Cough Patients Adenosine Triphosphate, Capsaicin, Functional Brain Imaging - Cough | Not applicable | Completed | Stuart Mazzone | 58 | 2019-03-01 | 2024-08-22 |
| Pyridoxine, P2 Receptor Antagonism, and ATP-mediated Vasodilation in Young Adults Adenosine Triphosphate, Acetylcholine, Sodium Nitroprusside - Receptor Blockade | Early Phase 1 | Completed | Colorado State University | 9 | 2019-02-07 | 2021-07-27 |
| ATP and Capsaicin Cough Provocation Test in Chronic Cough and Bronchiectasis Adenosine Triphosphate, capsaicin - Chronic Cough, Bronchiectasis | Unknown | Guangzhou Institute of Respiratory Disease | 200 | 2018-10-29 | 2020-02-11 | |
| Rapid Antidepressant Effects of ATP and Phosphocreatine Placebo, ATP, Phosphocreatine - Major Depressive Disorder | Phase 2 | Unknown | Zhujiang Hospital | 42 | 2017-05-03 | 2017-05-08 |
| A Time-to-effect Based Dosing Strategy in Cryoballoon Ablation of Patients With Paroxysmal Atrial Fibrillation Conventional cryotherapy dosage, Experimental cryotherapy dosage, Arctic Front Advance ST Cryoenergy Balloon Catheter - Atrial Fibrillation | Not applicable | Completed | Fundación para la Investigación del Hospital Clínico de Valencia | 140 | 2015-12-01 | 2019-08-15 |
| ATP in Alzheimer Disease ADENOSINE TRIPHOSPHATE, PLACEBO - Alzheimer's Disease | Phase 2 | Completed | Sara Varea | 20 | 2014-12-01 | 2017-03-29 |
| Study of Resting and Exercising Body Functioning in Freeman-Sheldon Syndrome and Related Conditions Lactate, Glucose, and Adenosine Triphosphate Blood Levels, Physiological Stress Test, Functional Enquiry Form - Arthrogryposis, Craniofacial Abnormalities | Withdrawn | Freeman-Sheldon Research Group, Inc. | 2014-03-01 | 2022-06-06 | ||
| Internet-delivered Attention Training for Obsessive-Compulsive Disorder Attention Training Program - Obsessive-Compulsive Disorder | Not applicable | Completed | Humboldt-Universität zu Berlin | 108 | 2013-10-01 | 2014-11-13 |
| Muscle Afferent Feedback Effects in Patients With Heart Failure Muscle Contraction with Metabolite Solution Administration - Chronic Heart Failure | Phase 1 | Completed | University of Utah | 144 | 2013-09-01 | 2018-01-08 |
| Study to Examine the Effects of ATP Supplementation on Muscle Excitability and Reaction Time During and Following a Repeated Sprint Bout Placebo, ATP - Muscle Fatigue Caused by Repetitive Muscle Exercise | Not applicable | Completed | Metabolic Technologies Inc. | 42 | 2013-07-01 | 2015-09-28 |
| Cimzia Versus Cimzia Plus Azathioprine in the Treatment of Active Crohn's Disease Certolizumab pegol, Azathioprine - Crohn's Disease | Phase 3 | Unknown | Gastroenterology Research of America | 65 | 2013-03-01 | 2013-03-26 |
| The Effects of HMB, ATP, and HMB Plus ATP on Muscle Mass, Strength, and Power in Resistance Trained Athletes Placebo, HMB, Peak ATP and HMB - Healthy Experienced Weight Training Males | Not applicable | Completed | Metabolic Technologies Inc. | 44 | 2012-01-01 | 2017-08-01 |
| Retinoids in ANCA Small Vessel Vasculitis: Silencing Autoantigens Retinoic acid, Standard of care - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Phase 2 | Withdrawn | University of North Carolina, Chapel Hill | 2012-01-01 | 2017-02-23 | |
| Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions PTSD Checklist-Specific, Modified Flanagan Quality of Life Scale, Center for Epidemiologic Studies Depression Scale - Arthrogryposis, Craniofacial Abnormalities | Terminated | Freeman-Sheldon Research Group, Inc. | 6 | 2011-02-01 | 2017-04-04 | |
| Study to Evaluate ATP-induced Pain and ATP-induced Dermal Vasodilation by Iontophoresis (0000-118)(COMPLETED) Comparator: Iontophoresis and Laser Doppler with ATP, Comparator: Iontophoresis and Laser Doppler with Saline - Osteoarthritis Pain | Phase 1 | Completed | Merck Sharp & Dohme LLC | 44 | 2009-10-01 | 2015-07-30 |
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Arthrogryposis (2) · Asthma (2) · Chronic Cough (2) · Craniofacial Abnormalities (2) · Depression (2) · Glomerulonephritis, IGA (2) · Proteinuria (2) · Alzheimer Disease (1) · Aneurysm (1) · Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (1) · Atrial Fibrillation (1) · Bronchiectasis (1) · Cachexia (1) · Cough (1) · Crohn Disease (1)
A. Manzoni Hospital (2) · Colorado State University (2) · Freeman-Sheldon Research Group, Inc. (2) · Metabolic Technologies Inc. (2) · Dartmouth-Hitchcock Medical Center (1) · Egyptian International Pharmaceutical Industries Co (1) · Fundación para la Investigación del Hospital Clínico de Valencia (1) · Gastroenterology Research of America (1) · Guangzhou Institute of Respiratory Disease (1) · Humboldt-Universität zu Berlin (1) · Imperial College London (1) · Maastricht University Medical Center (1) · Mahidol University (1) · McMaster University (1) · Merck Sharp & Dohme LLC (1)
United States (11) · China (3) · Spain (2) · Australia (1) · Canada (1) · Germany (1) · Guatemala (1) · Italy (1) · Mexico (1) · Nepal (1) · Netherlands (1) · Switzerland (1) · United Kingdom (1)
Frank Dinenno, PhD (2) · John A Rathmacher, PhD (2) · Antonello Pani, MD (1) · Betty Diamond, MD (1) · Bin Zhang, MD & PhD (1) · Carlo M Taboada, MD (1) · Charles W Randall, MD (1) · Claudio Ponticelli, MD (1) · Claudio Pozzi, MD (1) · David Wofsy, MD (1) · Francesco Locatelli, MD (1) · Gian B Fogazzi, MD (1) · Ke-fang Lai, MD (1) · Lionel D. Lewis, MD (1) · Markus Amann, PhD (1)
PMID 24330670, PMID 25403681, PMID 25590209, PMID 25779381, PMID 26174733, PMID 26178231, PMID 26494722, PMID 28034943, PMID 28264711, PMID 29247029, PMID 30626424
P01DK058335 (1)