57 completed, 17 recruiting, 12 unknown, 10 terminated. 113 Phase 3, 15 Phase 2.
Follow Vasculitis: new trials by email Literature Review of Vasculitis trials Research Report on Vasculitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Aspirin for the Prevention of Ischemic Complications in Giant Cell Arteritis Acetyl Salicylic Acid (ASA), Placebo - Giant Cell Arteritis (GCA), Acute Coronary Syndrome (ACS) | Phase 3 | Not yet recruiting | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | 120 | 2027-10-01 | 2026-10-30 |
| Reducing Arterial Inflammation Using Eplerenone and Statins in HIV Eplerenone, Placebo - HIV (Human Immunodeficiency Virus), Cardiovascular Diseases (CVD) | Phase 2 / Phase 3 | Not yet recruiting | Massachusetts General Hospital | 124 | 2027-03-01 | 2026-10-23 |
| Evaluation of Botulinum TOXin Type A in the Treatment of Buerger's Disease BOTOX INJECTION - Buerger Disease, Raynaud Syndrome | Phase 3 | Not yet recruiting | University Hospital, Toulouse | 8 | 2027-01-01 | 2026-07-23 |
| Efficacy and Safety of Immunoglobulin Plus Firsekibart in Patients With Kawasaki Disease IVIG, Aspirin, Firsekibart - Kawasaki Disease | Phase 2 / Phase 3 | Not yet recruiting | Children's Hospital of Fudan University | 90 | 2026-11-01 | 2026-10-22 |
| Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued Treatment Benralizumab - Asthma, Eosinophilic Granulomatosis With Polyangiitis (EGPA) | Phase 3 | Recruiting | AstraZeneca | 230 | 2026-07-24 | 2026-10-27 |
| Treatment for Giant Cell Arteritis With Tocilizumab and 8 as Compared to 26 Weeks of Prednisone Prednisone - Giant Cell Arteritis (GCA) | Phase 3 | Not yet recruiting | Insel Gruppe AG, University Hospital Bern | 178 | 2026-07-01 | 2026-05-01 |
| Statins Study in Children of Acute Kawasaki Disease With Coronary Artery Abnormalities atorvastatin of dose level 1, atorvastatin of dose level 2, atorvastatin of dose level 3 - Kawasaki Disease, Coronary Artery Abnormalities | Phase 3 | Recruiting | Children's Hospital of Fudan University | 9 | 2026-06-08 | 2026-06-16 |
| TAVNEOS for Otolaryngologic Manifestations of Granulomatosis With Polyangiitis Avacopan, Placebo - Granulomatosis With Polyangiitis, Wegener's | Phase 2 / Phase 3 | Recruiting | Robert Spiera, MD | 30 | 2026-05-22 | 2026-09-02 |
| Avacopan Added to Standard-of-care Therapy in ANCA-associated Vasculitis With Severe Kidney Involvement Avacopan, Placebo - ANCA-Associated Vasculitis (AAV) | Phase 3 | Not yet recruiting | University Hospital, Toulouse | 130 | 2026-03-01 | 2026-01-28 |
| Safe Effective Therapy With Low-Dose Glucocorticoid in ANCA-Associated Vasculitis (SAFE-LOW) Cyclophosphamide, Standard of Care (SOC), Prednisone - Granulomatosis With Polyangiitis, Microscopic Polyangiitis (MPA) | Phase 3 | Recruiting | Ottawa Hospital Research Institute | 36 | 2025-11-10 | 2026-01-30 |
| BDB-001 Phase III Trial in ANCA-Associated Vasculitis BDB-001 injection, Cyclophosphamide, Rituximab - ANCA Associated Vasculitis (AAV) | Phase 3 | Recruiting | Staidson (Beijing) Biopharmaceuticals Co., Ltd | 300 | 2025-11-10 | 2026-08-13 |
| Randomized Controlled Multicenter Study Comparing Steroid Therapy Plus Anticoagulants to Steroid Therapy Alone in Deep Venous Thrombosis of Behçet's Syndrome Corticosteroids + Rivaroxaban, Corticosteroids alone - Behcet Syndrome | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 134 | 2025-06-24 | 2026-04-23 |
| Study of Ravulizumab in Pediatric Participants With Primary IgAN Ravulizumab - IgAN, IgAVN | Phase 3 | Recruiting | Alexion Pharmaceuticals, Inc. | 36 | 2025-06-14 | 2026-07-30 |
| Study of Salvage Therapy to Treat Patients With Granulomatosis With Polyangiitis Rituximab, Tocilizumab, Tofacitinib - Granulomatosis With Polyangiitis, Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 42 | 2025-06-06 | 2026-04-03 |
| Immunosuppressive Therapy Alone Versus Plus Oral Anticoagulation in the Treatment of VT Associated With Behcet's Disease Placebo plus immunosuppression, Rivaroxaban plus immunosupression - Behcet Disease, Behcet Disease and Vascular Involvement | Phase 3 | Not yet recruiting | Marmara University | 110 | 2025-04-30 | 2025-04-13 |
| A Trial to Investigate Benralizumab in Children With Eosinophilic Diseases Benralizumab - Eosinophilic Granulomatosis With Polyangiitis (EGPA), Hypereosinophilia Syndrome (HES) | Phase 3 | Recruiting | AstraZeneca | 14 | 2025-04-17 | 2026-10-28 |
| Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV. Avacopan - Vasculitis | Phase 3 | Active not recruiting | Amgen | 19 | 2024-10-22 | 2026-07-20 |
| TocilizuMab discontinuAtion in GIant Cell Arteritis Tocilizumab treatment, questionnaires, Blood samples - Giant Cell Arteritis | Phase 3 | Active not recruiting | Centre Hospitalier Universitaire Dijon | 120 | 2024-05-13 | 2026-05-04 |
| A Study to Evaluate the Efficacy and Safety of SHR-1703 in Subjects With Eosinophilic Granulomatosis With Polyangiitis （EGPA） SHR-1703, Mepolizumab Injection - Eosinophilic Granulomatosis With Polyangiitis | Phase 2 / Phase 3 | Recruiting | Guangdong Hengrui Pharmaceutical Co., Ltd | 166 | 2023-11-16 | 2025-12-04 |
| A Study of Efficacy and Safety of Hemay005 Tablets in Patients With Behçet's Disease Hemay005, Placebo - Behçet's Disease | Phase 3 | Recruiting | Ganzhou Hemay Pharmaceutical Co., Ltd | 162 | 2023-11-13 | 2025-04-08 |
Showing 20 of 113. Sign in to see all of them.
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (21) · Giant Cell Arteritis (20) · Granulomatosis with Polyangiitis (20) · Microscopic Polyangiitis (15) · Behcet Syndrome (13) · Mucocutaneous Lymph Node Syndrome (13) · Churg-Strauss Syndrome (11) · Takayasu Arteritis (7) · Systemic Vasculitis (6) · Phlebitis (5) · Thrombophlebitis (5) · Lupus Erythematosus, Systemic (4) · Vascular Diseases (4) · Arteritis (3)
Cardiovascular Diseases (110) · Vascular Diseases (109) · Skin and Connective Tissue Diseases (100) · Skin Diseases (98) · Skin Diseases, Vascular (96) · Immune System Diseases (68) · Autoimmune Diseases (64) · Nervous System Diseases (37) · Brain Diseases (36) · Central Nervous System Diseases (36) · Systemic Vasculitis (36) · Cerebrovascular Disorders (34) · Hemic and Lymphatic Diseases (28) · Arteritis (26)
Prednisone (14) · Rituximab (14) · Cyclophosphamide (13) · Azathioprine (12) · Immunoglobulins, Intravenous (8) · Adrenal Cortex Hormones (6) · Infliximab (6) · Prednisolone (6) · mepolizumab (6) · Glucocorticoids (5) · tocilizumab (5) · Methotrexate (4) · avacopan (4) · Abatacept (3) · Aspirin (3)
Assistance Publique - Hôpitaux de Paris (19) · Cambridge University Hospitals NHS Foundation Trust (6) · Amgen (5) · Children's Hospital of Fudan University (5) · GlaxoSmithKline (4) · AstraZeneca (3) · Novartis Pharmaceuticals (3) · University Hospital, Toulouse (3) · University of Pennsylvania (3) · AbbVie (2) · Centre Hospitalier Universitaire Dijon (2) · Chinese SLE Treatment And Research Group (2) · Hoffmann-La Roche (2) · Massachusetts General Hospital (2) · Peking Union Medical College Hospital (2)
France (50) · United States (34) · Canada (23) · Italy (21) · United Kingdom (21) · Germany (18) · China (16) · Spain (15) · Belgium (14) · Japan (14) · Netherlands (13) · Israel (12) · Australia (10) · Sweden (10) · Turkey (Türkiye) (10)
Peter A Merkel, MD, MPH (4) · Jeffrey P Krischer, PhD (3) · Loic Guillevin, MD, PhD (3) · Carol A Langford, MD, MHS (2) · David Jayne (2) · David Jayne, MD (2) · John H. Stone, MD, MPH (2) · Xinping Tian, MD (2)
PMID 28592297, PMID 39425055, PMID 10068416, PMID 12401245, PMID 12905485, PMID 15751091, PMID 15838068, PMID 15986348, PMID 16221103, PMID 16378799, PMID 16646004, PMID 16914703, PMID 17332971, PMID 17407214, PMID 17557758, PMID 18163506, PMID 19109574, PMID 19451574, PMID 20054700, PMID 20647199, PMID 21060104, PMID 22127969, PMID 22975753, PMID 23290985, PMID 23305955, PMID 23528439, PMID 23615499, PMID 23754238, PMID 23897775, PMID 23901839, PMID 23902481, PMID 24572997, PMID 25047592, PMID 25372085, PMID 25776953, PMID 26387933, PMID 26621483, PMID 27049404, PMID 27310969, PMID 27696762, PMID 27924855, PMID 28246067, PMID 28270229, PMID 28514601, PMID 28605168, PMID 28678392, PMID 28745999, PMID 29386515, PMID 29695500, PMID 29724729
2023 (6), 2016 (4), 2018 (3), 2009 (2), 2014 (2), 2017 (2), R01HL115041 (2), U54AR057319 (2), 2015 (1), 2019 (1), R01HD066139 (1), R01HL033233 (1)