16 completed, 5 recruiting, 5 unknown, 2 withdrawn. 19 Not applicable, 4 Phase 3, 4 Phase 4, 3 Phase 2, 1 Early Phase 1.
Follow Vaginal Dryness: new trials by email Literature Review of Vaginal Dryness trials Research Report on Vaginal Dryness
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| VEDA Study (DHEA vs Estradiol) DHEA ovals, Estradiol 0.01% Vag Cream - Post-menopause, Pre-menopause | Not applicable | Recruiting | University of Arizona | 324 | 2026-08-04 | 2026-09-21 |
| F-GYN for Vaginal Dryness and Vulvovaginal Atrophy F-GYN Non-Crosslinked Hyaluronic Acid Injectable Gel, Standard Non-Hormonal Symptomatic Care - Atrophic Vaginitis, Atrophic Vulvovaginitis | Not applicable | Recruiting | Biovico Sp. z o.o. | 130 | 2026-07-24 | 2026-10-01 |
| Retrospective Cohort Study of Symptoms and Quality of Life in Women With Genitourinary Syndrome of Menopause. Vulvar Atrophy, Vulvovaginal Signs and Symptoms | Not yet recruiting | Mucosa Innovations, S.L. | 100 | 2026-07-01 | 2026-07-30 | |
| Exploration of the Effect of a Wheat Polar Lipid Complex on Vaginal Dryness in Healthy Postmenopausal Women Wheat Polar Lipid Complex, Placebo - Vaginal Dryness, Menopause Symptoms | Not applicable | Recruiting | Seppic | 110 | 2026-02-02 | 2026-10-19 |
| Efficacy and Safety of Vaginal Radiofrequency for Vulvovaginal Atrophy in Breast Cancer Patients GynWave-360, Local hydratation - Vaginal Dryness, Breast Cancer | Not applicable | Recruiting | Centre Oscar Lambret | 75 | 2025-06-12 | 2026-03-18 |
| Pilot Study of Individualized Treatment for Genitourinary Syndrome of Menopause in Women After Cancer Treatment Non-ablative vaginal Er:YAG laser therapy, Standard care - Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness | Not applicable | Active not recruiting | Institute of Oncology Ljubljana | 65 | 2024-10-15 | 2026-02-19 |
| Performance and Safety of MUCOGYNE® Ovule as a Moisturizer Mucogyne Ovule - Vaginal Dryness | Not applicable | Terminated | Biocodex | 33 | 2024-04-11 | 2025-04-13 |
| Changes in the Impact of Genitourinary Syndrome of Menopause With a Novel Nonhormonal Vulvovaginal Gel Assessed by PROMs. Hormone-free vulvovaginal gel with the tested composition XCMIM20m - Vulvar Atrophy, Vulvovaginal Signs and Symptoms | Not applicable | Recruiting | Mucosa Innovations, S.L. | 80 | 2024-01-08 | 2026-03-30 |
| Assess Efficacy, Safety, and Tolerability of 8 Weeks of Vaginal Hyaluronic (V-HYAL) Gel in Peri- and Post-Menopausal Female Vaginal Hyal gel 2.5g - Vaginal Dryness | Phase 4 | Completed | University of Malaya | 70 | 2024-01-08 | 2025-05-09 |
| Evaluation of the Efficacy and Safety of Mucogye® Gel as a Moisturizer Mucogyne Gel - Vaginal Dryness | Not applicable | Completed | Biocodex | 34 | 2023-10-10 | 2026-02-19 |
| Effectiveness and Safety of a Water-based and a Silicone-based Personal Lubricants With Sensory Action Lubricant A (sensate water-based personal lubricant) and Comparator A (non-sensate water-based lubricant), Lubricant B (sensate silicone-based personal lubricant) and Comparator B (non-sensate silicone-based personal lubricant) - Dyspareunia, Vaginal Dryness | Not applicable | Completed | Reckitt Benckiser Healthcare (UK) Limited | 132 | 2023-02-20 | 2025-02-11 |
| To Assess Signs and Symptoms in Women Affected by GSM After One Cycle of Pixel CO2-Alma Fractionated Laser Fractionated Laser (Pixel CO2-Alma), Fractionated Laser (Pixel CO.2-Alma) - Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness | Not applicable | Unknown | Dr. Filippo Murina | 70 | 2022-01-30 | 2021-12-14 |
| A Clinical Investigation Into the Effectiveness and Safety of Five Water Based Personal Lubricants. Lubricant A, Lubricant B, Lubricant C - Dyspareunia, Vaginal Dryness | Phase 3 | Completed | Reckitt Benckiser Healthcare (UK) Limited | 183 | 2021-03-01 | 2021-07-02 |
| Acceptability, Under Use in Real Conditions Of Two Vaginal Moistures Indicated for Women With Vaginal Drying Belamy (vaginal moisturizer) - Vaginal Dryness | Not applicable | Completed | Libbs Farmacêutica LTDA | 74 | 2020-04-06 | 2020-04-13 |
| Evaluation of Viscosity of a Vaginal Moisturizer sodium lactate and combination of polymers - Vaginal Dryness, Menopausal Women | Phase 4 | Unknown | Farmoquimica S.A. | 33 | 2019-01-14 | 2018-12-21 |
| Laser Therapy Following Radiotherapy for Gynecological Cancer Microablative Fractional CO2 Laser Therapy - Pelvic Radiotherapy, Gynecological Cancer | Not applicable | Unknown | National and Kapodistrian University of Athens | 112 | 2018-11-15 | 2019-07-30 |
| Carbon Dioxide Fractional Laser in Treating Participants With Stage 0-III Hormone Receptor-Positive Breast Cancer With Vulvovaginal Atrophy Carbon Dioxide Fractional Laser, Questionnaire Administration - Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | Phase 2 | Withdrawn | Mayo Clinic | 2018-09-10 | 2023-01-06 | |
| Fractional CO2 Laser Therapy in Minimizing Genitourinary Syndrome of Menopause in Gynecological Cancer Survivors Laser Therapy, Questionnaire Administration, Sham Intervention - Cervical Carcinoma, Dyspareunia | Not applicable | Completed | Ohio State University Comprehensive Cancer Center | 19 | 2018-05-11 | 2022-04-22 |
| Fractional CO2 Laser Therapy for Survivors of Breast Malignancies Laser Therapy, Questionnaire Administration - Breast Carcinoma, Cancer Survivor | Not applicable | Completed | Ohio State University Comprehensive Cancer Center | 66 | 2017-11-16 | 2023-03-20 |
| Hybrid Fractional Laser for Symptoms of Genitourinary Syndrome of Menopause Hybrid Fractional Laser - Vaginal Atrophy, Sexual Dysfunction | Not applicable | Completed | Sciton | 60 | 2017-05-19 | 2020-08-11 |
Showing 20 of 31. Sign in to see all of them.
Dyspareunia (13) · Breast Neoplasms (6) · Urinary Incontinence (3) · Sexual Dysfunction, Physiological (2) · Uterine Cervical Neoplasms (2) · Atrophic Vaginitis (1) · Breast Carcinoma In Situ (1) · Dysuria (1) · Endometrial Neoplasms (1) · Hot Flashes (1) · Orgasm (1) · Ovarian Neoplasms (1) · Pain (1) · Paresthesia (1) · Sexuality (1)
Urogenital Diseases (15) · Female Urogenital Diseases (14) · Female Urogenital Diseases and Pregnancy Complications (14) · Genital Diseases (14) · Male Urogenital Diseases (14) · Genital Diseases, Female (13) · Genital Diseases, Male (13) · Mental Disorders (13) · Sexual Dysfunctions, Psychological (13) · Sexual Dysfunction, Physiological (12) · Neoplasms (8) · Neoplasms by Site (8) · Breast Diseases (7) · Skin Diseases (7) · Skin and Connective Tissue Diseases (7)
Laser Therapy (2) · Vaginal Creams, Foams, and Jellies (2) · Estradiol (1) · Hyaluronic Acid (1) · Ospemifene (1) · Pilocarpine (1) · Standard of Care (1) · Testosterone (1)
Biocodex (2) · Farmoquimica S.A. (2) · Mucosa Innovations, S.L. (2) · Ohio State University Comprehensive Cancer Center (2) · Reckitt Benckiser Healthcare (UK) Limited (2) · Alliance for Clinical Trials in Oncology (1) · Biovico Sp. z o.o. (1) · Centre Oscar Lambret (1) · Creighton University (1) · Derming SRL (1) · Dr. August Wolff GmbH & Co. KG Arzneimittel (1) · Dr. Filippo Murina (1) · F&C Licorice Ltd (1) · Hadassah Medical Organization (1) · Institute of Oncology Ljubljana (1)
United States (7) · France (3) · Germany (3) · Italy (3) · Israel (2) · Spain (2) · Belgium (1) · Brazil (1) · Finland (1) · Greece (1) · Malaysia (1) · Poland (1) · Slovenia (1)
Allison Quick, MD (2) · Adele Sparavigna, Physician (1) · Boris Kaplan, MD (1) · Charles L. Loprinzi, MD (1) · Christoph Abels, Prof., MD (1) · Dianne Travers-Gustafson, PhD (1) · Drorith Hochner-Celnikier, MD (1) · Hasniza Zaman Huri Prof, Doctor of Philosophy (1) · Irene Su, MD MSCE (1) · Kirstin Deuble-Bente, Dr. (1) · Kirstin Deuble-Bente, Medical Doctor (1) · Klaus-Michael Grunwald, MD (1) · Laurent Simar, Dr (1)
PMID 40709601, PMID 21702402, PMID 25845406, PMID 28657769, PMID 30694917, PMID 31474161, PMID 33358206, PMID 37619252, PMID 42643155, PMID 42665344, PMID 42793498