13 completed, 9 unknown, 4 not yet recruiting, 4 terminated. 35 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 35 | Completed 13, Unknown 9, Not yet recruiting 4, Terminated 4, Withdrawn 3, Active not recruiting 2 |
Follow Uveitis: new trials by email Literature Review of Uveitis trials Research Report on Uveitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Therapeutic Drug Monitoring-baSed adalimuMab De-escalatiOn in nOn-infecTious cHronic Uveitis Blood sample, Adalimumab Injection - Uveitis, Chronic Disease | Phase 4 | Not yet recruiting | Centre Hospitalier Universitaire de Saint Etienne | 320 | 2026-12-01 | 2026-07-10 |
| Adalimumab Dose Adjustment for Pediatric Uveitis Treatment Trial Adalimumab/Biosimilar - Juvenile Idiopathic Arthritis Associated Uveitis, Uveitis, Anterior | Phase 4 | Not yet recruiting | Nisha Acharya | 160 | 2026-09-01 | 2026-07-13 |
| Impact Of Upadacitinib On The Frequency Of Acute Recurrent Anterior Uveitis In Patients With Axial Spondyloarthritis Upadacitinib 15 MG [Rinvoq] - Axial Spondylarthritis (axSpA) | Phase 4 | Not yet recruiting | CARE ARTHRITIS LTD. | 200 | 2026-05-01 | 2026-02-06 |
| Loteprednol Etabonate Versus Prednisolone Acetate for Anterior Chamber Granulomas loteprednol etabonate 1% arm 1, prednisolone acete 1% - Anterior Chamber Granulomatous Uveitis | Phase 4 | Completed | Fayoum University | 66 | 2025-08-10 | 2026-03-27 |
| An Interventional Study of Upadacitinib Extended-Release Tablets in Patients With Refractory Uveitis Upadacitinib Extended-Release Tablets - Uveitis | Phase 4 | Active not recruiting | Tianjin Medical University | 30 | 2025-01-01 | 2026-08-19 |
| Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases Recombinant Herpes Zoster Vaccine (RZV), MTX Discontinuation, MMF Discontinuation - Rheumatoid Arthritis, Spondylitis, Ankylosing | Phase 4 | Active not recruiting | University of Sao Paulo General Hospital | 2005 | 2023-05-23 | 2026-05-04 |
| A Study of the Effect of Different Doses of Difluprednate Eye Drops on the Intraocular Pressure After Phacoemulsification Difluprednate Eye Drops - Uveitis, Anterior | Phase 4 | Unknown | Kafrelsheikh University | 20 | 2022-11-01 | 2022-12-13 |
| Biologic Therapy in Pediatric JIA Uveitis biologic DMARDs - Juvenile Idiopathic Arthritis Associated Uveitis | Phase 4 | Unknown | Kasr El Aini Hospital | 250 | 2022-07-01 | 2022-10-04 |
| Fluocinolone Acetonide Intravitreal Implant 0.18 mg in the Treatment of Chronic Non-Infectious Posterior Segment Uveitis Fluocinolone Acetonide Intravitreal Implant 0.18 mg - Uveitis, Posterior | Phase 4 | Unknown | Alimera Sciences | 125 | 2022-06-06 | 2024-08-06 |
| Ixekizumab for the Management of Refractory Non-Infectious Uveitis: A Proof-of-Concept Study Ixekizumab Prefilled Syringe - Uveitis, Posterior, Uveitis, Anterior | Phase 4 | Unknown | Massachusetts Eye Research and Surgery Institution | 20 | 2022-06-01 | 2023-10-16 |
| Assessment of Safety , Clinical Efficacy With QLETLI in Non-infectious Uveitis (UV) QLETLI - Uveitis | Phase 4 | Completed | Bio-Thera Solutions | 60 | 2021-12-27 | 2026-10-13 |
| Ozurdex Monotherapy Trial Ozurdex 0.7mg Ophthalmic Implant, Prednisone - Uveitis, Posterior, Uveitis, Intermediate | Phase 4 | Withdrawn | Ottawa Hospital Research Institute | 2021-11-30 | 2025-03-12 | |
| Efficacy and Safety of Adalimumab Plus Medium Dose Oral Glucocorticosteroid for Refractory Behçet's Uveitis Adalimumab plus different doses of oral glucocorticosteroid - Uveitis | Phase 4 | Not yet recruiting | Peking Union Medical College Hospital | 130 | 2021-11-10 | 2021-11-03 |
| The Efficacy and Safety of Adalimumab in Non-infectious Anterior Pediatric Uveitis With Peripheral Vascular Leakage Adalimumab, Methotrexate - Uveitis, Anterior, Adalimumab | Phase 4 | Unknown | Peking Union Medical College Hospital | 50 | 2021-08-19 | 2021-11-10 |
| Adalimumab in JIA-associated Uveitis Stopping Trial Adalimumab, Placebo - Uveitis, JIA | Phase 4 | Completed | Nisha Acharya | 87 | 2020-03-15 | 2025-05-11 |
| Six-months Versus Nine-months ATT for Ocular TB Anti-Tuberculosis Treatment - Tuberculosis (TB), Uveitis | Phase 4 | Completed | L.V. Prasad Eye Institute | 58 | 2020-01-01 | 2024-09-26 |
| Safety and Effectiveness of Acthar Gel for Inflammation of the Eye's Uvea (Middle Layer) Acthar Gel - Uveitis, Posterior, Uveitis, Intermediate | Phase 4 | Terminated | Mallinckrodt | 5 | 2018-10-05 | 2021-08-03 |
| Macular Edema Nepafenac vs. Difluprednate Uveitis Trial Difluprednate, Nepafenac, Prednisolone acetate - Uveitis, Macular Edema | Phase 4 | Terminated | University of California, San Francisco | 9 | 2018-09-12 | 2021-01-13 |
| Saline vs. Lactated Ringers for Emergency Department IV Fluid Resuscitation Lactated Ringer Solution, Normal Saline 0.9% Infusion Solution Bag - Fluid Loss, Symptom Complex, Triple | Phase 4 | Completed | Nicholas M Mohr | 157 | 2017-05-23 | 2018-09-11 |
| Efficacy and Safety of H.P. ACTHAR GEL in Adults With Retinal Vasculitis H.P. ACTHAR GEL - Uveitis, Posterior, Vasculitis Retinal | Phase 4 | Unknown | Ocular Immunology and Uveitis Foundation | 40 | 2017-03-22 | 2019-09-12 |
Showing 20 of 35. Sign in to see all of them.
Uveitis, Anterior (10) · Uveitis, Posterior (9) · Uveitis, Intermediate (7) · Macular Edema (5) · Behcet Syndrome (4) · Panuveitis (3) · Retinal Vasculitis (3) · Axial Spondyloarthritis (2) · Spondylitis, Ankylosing (2) · Arthritis, Juvenile (1) · Arthritis, Rheumatoid (1) · Choroiditis (1) · Chronic Disease (1) · Dermatomyositis (1)
Uveal Diseases (35) · Eye Diseases (34) · Panuveitis (17) · Retinal Diseases (8) · Cardiovascular Diseases (6) · Vascular Diseases (6) · Vasculitis (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Macular Degeneration (5) · Retinal Degeneration (5) · Ankylosis (4) · Arthritis (4) · Bone Diseases (4) · Genetic Diseases, Inborn (4)
Adalimumab (6) · Adrenocorticotropic Hormone (3) · Fluocinolone Acetonide (3) · Infliximab (3) · Methotrexate (3) · Calcium Dobesilate (2) · Prednisone (2) · Adrenal Cortex Hormones (1) · Alkylating Agents (1) · Azathioprine (1) · Bimatoprost (1) · Biological Products (1) · Biosimilar Pharmaceuticals (1) · Blood Specimen Collection (1) · Certolizumab Pegol (1)
Nisha Acharya (2) · Peking Union Medical College Hospital (2) · Alimera Sciences (1) · Asan Medical Center (1) · Bio-Thera Solutions (1) · CARE ARTHRITIS LTD. (1) · Centre Hospitalier Universitaire de Saint Etienne (1) · Duke University (1) · Egla C. Rabinovich (1) · Fayoum University (1) · JHSPH Center for Clinical Trials (1) · Johns Hopkins University (1) · Kafrelsheikh University (1) · Kasr El Aini Hospital (1) · L.V. Prasad Eye Institute (1)
United States (16) · China (3) · Egypt (3) · United Kingdom (3) · Australia (2) · Brazil (2) · India (2) · Burma (1) · Canada (1) · Czechia (1) · Finland (1) · France (1) · Germany (1) · Iran (1) · Italy (1)
Nisha Acharya, MD MS (3) · Ahmed Hashem, PhD (1) · Alana M Santana, MD (1) · Antonio Cutino (1) · C. Stephen Foster, MD, FACS, FACR (1) · Douglas Jabs, MD, MBA (1) · Egla Rabinovich, MD. MPH (1) · Farhad Shahram, Professor (1) · Glenn J Jaffe, MD (1) · Grace L Clarke (1) · Janet T Holbrook, PhD, MPH (1) · Jennifer E Thorne, MD, PhD (1) · John Kempen, MD, PhD (1)
PMID 16406545, PMID 16461435, PMID 16545455, PMID 21652026, PMID 21840602, PMID 21861971, PMID 22247489, PMID 22409563, PMID 23163490, PMID 25115882, PMID 26501236, PMID 26798977, PMID 28445659, PMID 28477440, PMID 30146446, PMID 32918964, PMID 33854572, PMID 36600374, PMID 38925285, PMID 39863370, PMID 41679320, PMID 41919656, PMID 41932224, PMID 42261247, PMID 42294825, PMID 42843284
2005 (1), 2016 (1), 2023 (1), U10EY014660 (1), UG1EY029658 (1), UG1EY038172 (1)