2 completed, 1 recruiting, 1 terminated. 4 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Recruiting 1, Terminated 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
Follow Tuberculosis, MDR: new trials by email Literature Review of Tuberculosis, MDR trials Research Report on Tuberculosis, MDR
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Program for Rifampicin-Resistant Disease With Stratified Medicine for Tuberculosis Bedaquiline, Linezolid, Pretomanid - Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant | Phase 2 / Phase 3 | Recruiting | University of California, San Francisco | 400 | 2025-10-03 | 2026-09-02 |
| A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis Pretomanid, Bedaquiline, moxifloxacin - Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant | Phase 2 | Completed | Global Alliance for TB Drug Development | 26 | 2021-09-16 | 2025-01-17 |
| Adjunctive Acetylsalicylic Acid and Ibuprofen for Tuberculosis Control group, ASA group, IBU group - Tuberculosis, Pulmonary, Tuberculosis, MDR | Phase 2 | Terminated | Fundació Institut Germans Trias i Pujol | 426 | 2021-03-04 | 2026-06-01 |
| Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult Patients Pretomanid, Bedaquiline, Moxifloxacin - Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant | Phase 2 / Phase 3 | Completed | Global Alliance for TB Drug Development | 455 | 2018-07-30 | 2026-08-27 |
Tuberculosis (4) · Tuberculosis, Multidrug-Resistant (4) · Tuberculosis, Pulmonary (4) · Communicable Diseases (1) · Extensively Drug-Resistant Tuberculosis (1) · Latent Tuberculosis (1)
Actinomycetales Infections (4) · Bacterial Infections (4) · Bacterial Infections and Mycoses (4) · Gram-Positive Bacterial Infections (4) · Infections (4) · Lung Diseases (4) · Mycobacterium Infections (4) · Respiratory Tract Diseases (4) · Respiratory Tract Infections (4) · Disease Attributes (1) · Latent Infection (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
Moxifloxacin (3) · bedaquiline (3) · pretomanid (3) · Pyrazinamide (2) · Aspirin (1) · Control Groups (1) · Ethambutol (1) · Ibuprofen (1) · Isoniazid (1) · Linezolid (1) · Rifampin (1)
Global Alliance for TB Drug Development (2) · Fundació Institut Germans Trias i Pujol (1) · University of California, San Francisco (1)
Georgia (3) · South Africa (3) · Uganda (2) · Brazil (1) · Malaysia (1) · Mongolia (1) · Pakistan (1) · Peru (1) · Philippines (1) · Russia (1) · Tanzania (1) · Vietnam (1)
Antonio Lombardi, MD (1) · Cristina Vilaplana, MD, PhD (1) · Morounfolu Olugbosi, MD MSc (1)