8 completed, 5 unknown, 1 active not recruiting, 1 not yet recruiting. 7 Not applicable, 5 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Unknown 3, Completed 2, Not yet recruiting 1, Recruiting 1 |
| Phase 4 | 5 | Completed 3, Unknown 2 |
Follow Sugammadex: new trials by email Literature Review of Sugammadex trials Research Report on Sugammadex
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sugammadex-Induced Clenching During Neuromuscular Blockade Reversal Sugammadex 1 mg/kg Group, Sugammadex 2 mg/kg Group, Sugammadex 4 mg/kg Group - Neuromuscular Blockade Reversal Agent, Perioperative Complications | Not applicable | Recruiting | Wonkwang University Hospital | 240 | 2025-07-01 | 2026-07-07 |
| NMBA Reversal and Postoperative Urinary Retention Choice of reversal agent (sugammadex or neostigmine [with muscaranic antagonist]) - Neuromuscular Blocking Agents, Urinary Retention After Procedure | Active not recruiting | Beth Israel Deaconess Medical Center | 70000 | 2025-06-08 | 2026-01-23 | |
| Sugammadex on Laparoscopic Bariatric Surgery Sugammadex, Neostigmine - Laparoscopic Bariatric Surgery, Sugammadex | Not applicable | Not yet recruiting | Shanxi Bethune Hospital | 60 | 2024-12-01 | 2024-11-07 |
| Effectiveness on Smooth Extubation According to the Administration Time of Sugammadex sugammadex - Sugammadex, Extubation | Not applicable | Unknown | Ajou University School of Medicine | 66 | 2024-10-03 | 2024-07-25 |
| Quantitative Neuromuscular Monitoring and Gastric Bypass Surgery Quantitative Neuromuscular Function Monitoring - Sugammadex | Completed | University of California, Davis | 183 | 2024-01-08 | 2026-10-09 | |
| Postoperative Urinary Retention After Reversal of Neuromuscular Block by Neostigmine Versus Sugammadex Neostigmine, Sugammadex - Urinary Retention Postoperative, Laparoscopic Cholecystectomy | Phase 4 | Completed | University of Texas Southwestern Medical Center | 235 | 2023-09-11 | 2024-10-09 |
| Sugammadex and Time to Extubation in Ophthalmic Surgery sugammadex, Neostigmine + Atropine - General Anesthesia Using Endotracheal Intubation, Ophthalmologic Surgical Procedure | Completed | China Medical University Hospital | 262 | 2023-08-01 | 2024-10-08 | |
| Neostigmine Versus Sugammadex on Renal Functions Neostigmine, Sugammadex - Sugammadex, Neostigmine | Phase 4 | Unknown | Menoufia University | 64 | 2023-03-01 | 2023-10-13 |
| Comparative Efficacy and Safety of Sugammadex and Neostigmine Neostigmine and Sugammadex - Sugammadex | Not applicable | Unknown | Chang Gung Memorial Hospital | 200 | 2021-09-06 | 2022-03-10 |
| Effect of Muscle Relaxation Reversal on the Success Rate of Motor Evoked Potential Recording Sugammadex, Saline - Sugammadex, Motor Evoked Potentials | Not applicable | Completed | Beijing Tiantan Hospital | 170 | 2021-08-16 | 2022-09-21 |
| Diaphragm Ultrasound to Evaluate the Antagonistic Effect of Sugammadex sugammadex - Diaphragm Ultrasonography, Liver Dysfunction | Phase 4 | Unknown | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 99 | 2021-07-01 | 2021-09-05 |
| Comparison of the Effects of Sugammadex and Neostigmine on Early Extubation, Intensive Care Unit Admission and Length of Stay, and Hospital Costs in Adult Cranial Surgery Craniectomy, Sugammadex | Completed | Kanuni Sultan Suleyman Training and Research Hospital | 112 | 2021-05-01 | 2025-05-23 | |
| Effectiveness of Sugammadex on Muscle Relaxant Reversal in Preterm Neonates Sugammadex, Neostigmine - Sugammadex | Not applicable | Unknown | Alexandria University | 60 | 2020-08-11 | 2020-09-28 |
| The Effect of Sugammadex During Transcranial Electrical Motor Evoked Potential Monitoring in Spinal Surgery Sugammadex - Sugammadex | Not applicable | Completed | Beijing Tiantan Hospital | 66 | 2020-07-16 | 2021-04-06 |
| Comparison of QoR-15 in Laparoscopic Cholecystectomy: Sugammadex vs. Neostigmine Sugammadex, Neostigmine - Neuromuscular Blockade Reversal Agent, Sugammadex | Phase 4 | Completed | Seoul National University Bundang Hospital | 77 | 2020-02-24 | 2020-12-24 |
| Residual Paralysis and Reversal With Routine Neostigmine Versus Half-dose Sugammadex and Routine Neostigmine Neostigmine, Sugammadex - Neuromuscular Blockade, Sugammadex | Phase 4 | Completed | Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital | 113 | 2013-05-01 | 2021-10-04 |
Delayed Emergence from Anesthesia (1) · Liver Diseases (1) · Trismus (1) · Urinary Retention (1)
Pathological Conditions, Signs and Symptoms (2) · Digestive System Diseases (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Male Urogenital Diseases (1) · Nervous System Diseases (1) · Neurologic Manifestations (1) · Neuromuscular Manifestations (1) · Pathologic Processes (1) · Postoperative Complications (1) · Signs and Symptoms (1) · Spasm (1) · Urination Disorders (1) · Urogenital Diseases (1) · Urologic Diseases (1)
Sugammadex (14) · Neostigmine (9) · Atropine (1) · Epinephrine (1) · Population Groups (1) · Pyridostigmine Bromide (1) · S 1 (combination) (1) · Sodium Chloride (1)
Beijing Tiantan Hospital (2) · Ajou University School of Medicine (1) · Alexandria University (1) · Beth Israel Deaconess Medical Center (1) · Chang Gung Memorial Hospital (1) · China Medical University Hospital (1) · Kanuni Sultan Suleyman Training and Research Hospital (1) · Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital (1) · Menoufia University (1) · Seoul National University Bundang Hospital (1) · Shanxi Bethune Hospital (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · University of California, Davis (1) · University of Texas Southwestern Medical Center (1) · Wonkwang University Hospital (1)
China (3) · United States (3) · Egypt (2) · South Korea (2) · Taiwan (2) · Turkey (Türkiye) (1)
Ahmed M Elshafie (1) · Cheolhyeong Lee, MD (1) · Jian-Wen Zhang, MD (1) · Jiwon Han, Ms (1) · Luca J Wachtendorf, MD (1) · Maximilian S Schaefer, MD, PhD (1) · Ruquan Han, M.D., Ph.D (1) · Tiffany Moon, MD (1) · Yi-Ying Chiang, MD (1) · Yun Lin, MD, PhD. (1)
PMID 20876699, PMID 20885293, PMID 26634077, PMID 28399799, PMID 35105573, PMID 35501072, PMID 37626303, PMID 38686365, PMID 41789933