3 terminated, 2 completed, 2 unknown, 1 recruiting. 9 Phase 2, 3 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Terminated 3, Completed 2, Unknown 2, Recruiting 1, Withdrawn 1 |
| Phase 3 | 3 | Unknown 2, Completed 1 |
| Phase 1 | 1 | Terminated 1 |
Follow Status Asthmaticus: new trials by email Literature Review of Status Asthmaticus trials Research Report on Status Asthmaticus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pediatric Asthma Trial of Corticosteroid Heterogeneity (PATCH): Trial of Dexamethasone Versus Methylprednisolone for Pediatric Critical Asthma Dexamethasone (0.6mg/kg; Max 16mg) Once Daily, Dexamethasone (0.25 mg/kg/dose, Max dose 16mg) every 6-hours, Methylprednisolone - Asthma (Diagnosis) | Phase 2 | Recruiting | Johns Hopkins All Children's Hospital | 159 | 2026-08-01 | 2026-08-12 |
| Treating Exacerbations of Asthma With Oral Montelukast in Children Montelukast Oral Granules, Albuterol, Corticosteroid - Status Asthmaticus | Phase 2 | Completed | Vanderbilt University Medical Center | 90 | 2023-10-20 | 2026-07-02 |
| Non Invasive Positive Pressure Ventilation in Status Asthmaticus Noninvasive positive pressure ventilation - Status Asthmaticus | Phase 2 | Withdrawn | Southern Illinois University | 2011-06-01 | 2014-12-12 | |
| The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room Budesonide, Normal saline - Status Asthmaticus | Phase 2 / Phase 3 | Completed | King Saud University | 945 | 2010-11-01 | 2014-03-13 |
| Randomized, Placebo/Active Crossover Dose-ranging Study for Safety and Efficacy in Asthma Patients. E004 (epinephrine inhalation aerosol), 90 mcg/actuation, E004 Placebo, E004 (epinephrine inhalation aerosol), 125 mcg - Asthma | Phase 1 / Phase 2 | Terminated | Amphastar Pharmaceuticals, Inc. | 9 | 2009-12-01 | 2018-05-16 |
| Study Evaluating the Safety and Effects of MN-221 in Subjects Experiencing an Acute Exacerbation of Asthma Dose Group 1, MN-221 placebo, Dose Group 2 - Asthma, Status Asthmaticus | Phase 2 | Terminated | MediciNova | 29 | 2008-06-01 | 2011-10-07 |
| Montelukast With Status Asthmaticus, Ages 2-5 Montelukast, Sterile water - Status Asthmaticus, Asthma | Phase 2 / Phase 3 | Unknown | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 52 | 2006-12-01 | 2008-12-16 |
| Montelukast With Status Asthmaticus, Ages 6-18 Montelukast, sterile water - Status Asthmaticus, Asthma | Phase 2 / Phase 3 | Unknown | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 52 | 2006-12-01 | 2008-12-16 |
| Heliox-Powered Albuterol Therapy in the Treatment of Children Admitted With Acute Asthma Exacerbation Helium-oxygen-driven albuterol nebulizer, Oxygen - Status Asthmaticus | Phase 2 | Terminated | Children's Hospital Medical Center, Cincinnati | 42 | 2006-04-01 | 2010-11-08 |
Asthma (7) · Disease (1) · Dyspnea (1) · Respiratory Sounds (1)
Bronchial Diseases (9) · Hypersensitivity (9) · Hypersensitivity, Immediate (9) · Immune System Diseases (9) · Respiratory Hypersensitivity (9) · Respiratory Tract Diseases (9) · Lung Diseases (7) · Lung Diseases, Obstructive (7) · Asthma (2) · Pathological Conditions, Signs and Symptoms (2) · Pathologic Processes (1) · Respiration Disorders (1) · Signs and Symptoms (1) · Signs and Symptoms, Respiratory (1)
montelukast (3) · Adrenal Cortex Hormones (1) · Albuterol (1) · Budesonide (1) · Dexamethasone (1) · Epinephrine (1) · MAX protein, human (1) · Methylprednisolone (1) · Oxygen (1) · Saline Solution (1) · bedoradrine (1)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2) · Amphastar Pharmaceuticals, Inc. (1) · Children's Hospital Medical Center, Cincinnati (1) · Johns Hopkins All Children's Hospital (1) · King Saud University (1) · MediciNova (1) · Southern Illinois University (1) · Vanderbilt University Medical Center (1)
United States (8) · Saudi Arabia (1)
Abdullah A Alangari, MBBS (1) · Derek S Wheeler, M.D. (1) · Donald H Arnold, MD, MPH (1) · Jeffrey Blumer, MD (1) · Jeffrey L. Blumer, M.D., Ph.D. (1) · Jim Shi, M.D., Ph.D. (1) · Meghan Sorondo, PharmD (1) · Michael Kalafer, MD (1) · Sangita Basnet, MD (1)
PMID 23949578, PMID 24384609, PMID 28639856, PMID 31056949, PMID 32150492, PMID 32960980