6 completed, 1 enrolling by invitation, 1 unknown. 5 Not applicable, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 3, Enrolling by invitation 1, Unknown 1 |
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow Sprue, Tropical: new trials by email Literature Review of Sprue, Tropical trials Research Report on Sprue, Tropical
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| OCT Guided Trans Nasal Imaging of the Small Intestine in Adults TNIB Catheter - Environmental Enteric Dysfunction | Not applicable | Enrolling by invitation | Massachusetts General Hospital | 30 | 2017-09-22 | 2026-11-10 |
| Effectiveness of Point-of-use Water Treatment Technologies to Prevent Stunting Among Children in South Africa Silver-impregnated ceramic tablet, Silver-impregnated ceramic water filter, Safe-storage water container - Diarrhoea;Infectious;Presumed, Diarrhea, Infantile | Not applicable | Completed | University of Virginia | 415 | 2016-06-01 | 2025-07-15 |
| Intervention and Mechanisms of Alanyl-Glutamine for Inflammation, Nutrition, and Enteropathy Alanyl-Glutamine - Malnutrition, Environmental Enteropathy | Phase 3 | Completed | Children's Hospital Medical Center, Cincinnati | 112 | 2013-10-01 | 2016-08-01 |
| WASH Benefits Kenya Water Quality, Sanitation, Handwashing - Malnutrition, Diarrhea | Not applicable | Completed | Innovations for Poverty Action | 8246 | 2012-11-01 | 2018-07-12 |
| WASH Benefits Bangladesh Water quality, Sanitation, Hand washing - Malnutrition, Diarrhea | Not applicable | Unknown | International Centre for Diarrhoeal Disease Research, Bangladesh | 5040 | 2012-05-01 | 2022-04-13 |
| Exploration of the Biologic Basis for Underperformance of Oral Polio and Rotavirus Vaccines in INDIA (PROVIDE) IPV vaccination - Poliomyelitis, Tropical Enteropathy | Phase 1 | Completed | International Vaccine Institute | 372 | 2012-03-01 | 2017-08-31 |
| Exploration of the Biologic Basis for Underperformance of Oral Polio and Rotavirus Vaccines in Bangladesh IPV (inactivated polio vaccine), Rotarix - Rotavirus Diarrhea, Vaccine Virus Shedding | Phase 3 | Completed | University of Vermont | 700 | 2011-05-01 | 2025-04-29 |
| Trial of Rifaximin in the Treatment of Tropical Enteropathy Rifaximin, Placebo - Tropical Enteropathy | Not applicable | Completed | Washington University School of Medicine | 147 | 2007-09-01 | 2019-11-12 |
Diarrhea (3) · Malnutrition (3) · Breast Feeding (2) · Intestinal Diseases, Parasitic (2) · Nutrition Disorders (2) · Child Nutrition Disorders (1) · Diarrhea, Infantile (1) · Disease (1) · Intestinal Diseases (1) · Poliomyelitis (1)
Digestive System Diseases (8) · Gastrointestinal Diseases (8) · Malabsorption Syndromes (8) · Metabolic Diseases (8) · Nutritional and Metabolic Diseases (8) · Intestinal Diseases (7) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (4) · Signs and Symptoms, Digestive (4) · Infections (3) · Behavior (2) · Feeding Behavior (2) · Nutrition Disorders (2) · Parasitic Diseases (2) · Central Nervous System Diseases (1)
Hand Disinfection (2) · Nutritional Status (2) · Sanitation (2) · Water Quality (2) · Aging (1) · Poliovirus Vaccine, Inactivated (1) · RIX4414 vaccine (1) · Rifaximin (1) · alanylglutamine (1)
Children's Hospital Medical Center, Cincinnati (1) · Innovations for Poverty Action (1) · International Centre for Diarrhoeal Disease Research, Bangladesh (1) · International Vaccine Institute (1) · Massachusetts General Hospital (1) · University of Vermont (1) · University of Virginia (1) · Washington University School of Medicine (1)
Bangladesh (2) · Brazil (1) · India (1) · Kenya (1) · Malawi (1) · South Africa (1) · United States (1)
Beth Kirkpatrick, M.D. (2) · Aldo Lima, MD, PhD (1) · Amy Pickering, PhD (1) · Ayan Dey, Ph.D (1) · Christine Stewart, PhD (1) · Clair Null, PhD (1) · Guillermo Tearney, M.D, PhD. (1) · Mark J Manary (1) · Pascal O Bessong, PhD (1) · Ranjan K Nandy, M.D. (1) · Rashidul Haque, M.D., Ph.D. (1) · Rebecca Dillingham, MD, MPH (1) · Sean R Moore, MD, MS (1) · Stephen P Luby, MD (1) · Suman Kanungo, M.D. (1)
PMID 23996605, PMID 30624600, PMID 26643930, PMID 26870801, PMID 27075905, PMID 27154394, PMID 27217217, PMID 28194449, PMID 28293424, PMID 28444240, PMID 28980942, PMID 29378045, PMID 29390150, PMID 29394355, PMID 29396219, PMID 29514306, PMID 29616235, PMID 29616236, PMID 29669039, PMID 29976234, PMID 29976251, PMID 30517728, PMID 30963177, PMID 31050672, PMID 31242190, PMID 32157282, PMID 32826717, PMID 32867719, PMID 33407549, PMID 34086447, PMID 34319986, PMID 34494545, PMID 34565452, PMID 35939520, PMID 38378704, PMID 38670986, PMID 39052701, PMID 40454163, PMID 41401135, PMID 41467215, PMID 42454929