63 completed, 33 unknown, 13 recruiting, 10 not yet recruiting. 85 Not applicable, 7 Phase 3, 4 Phase 2, 4 Phase 4, 1 Phase 1.
Follow Skull Fractures: new trials by email Literature Review of Skull Fractures trials Research Report on Skull Fractures
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimized Osteosynthesis: Bone Mineral Density Recovery in Mandibular Body Fractures Using Patient-Specific Versus Conventional Plates Open reduction and Internal fixation of a mandibular body fracture - Mandibular Fractures | Not applicable | Recruiting | Cairo University | 26 | 2026-10-12 | 2026-10-29 |
| Epidemiological and Statistical Study of Facial Traumatic Fractures at Assiut University Trauma Hospital Facial Fractures, Maxillofacial Injuries | Not yet recruiting | Assiut University | 50 | 2026-10-01 | 2026-09-18 | |
| Custom-Made Titanium Plates Versus Custom-Made Polyether Ether Ketone (PEEK) Plates Custom-Made Titanium Plate, Custom-Made PEEK Plate - Mandibular Fractures | Not applicable | Recruiting | Mansoura University | 32 | 2026-09-24 | 2026-10-09 |
| Virtual Surgical Planning and Preoperative Plate Bending for Maxillofacial Fractures Conventional Open Reduction and Internal Fixation With Intraoperative Plate Bending, Virtual Surgical Planning-Assisted Open Reduction and Internal Fixation With Preoperative Plate Bending - Mandibular Fractures, Maxillofacial Injuries | Not applicable | Not yet recruiting | University of Medicine and Pharmacy at Ho Chi Minh City | 30 | 2026-09-20 | 2026-10-02 |
| Safety-zone Approach and Facial Nerve Preservation in Transbuccal-accessed Fixation of Mandibular Fractures Landmarking Safety-zone - Facial Nerve Injuries, Mandibular Fractures | Not applicable | Recruiting | Delta University for Science and Technology | 16 | 2026-09-05 | 2026-09-09 |
| A Trial to Evaluate Two Ectropion Preventive Measures Using the Subciliary Approach in Orbital Fracture Surgery. Subciliary Approach, Lateral Canthopexy, Orbicularis Oculi Suspension - Orbital Fractures, Orbital Floor Fractures | Not applicable | Not yet recruiting | Minia University | 30 | 2026-09-01 | 2026-08-20 |
| Effect of Adipose Tissue Derived Autologous Mesenchymal Stem Cell Concentrate on Bone Quality in Mandibular Fracture Healing. Adipose tissue derived mesenchymal stem cells concentrate application in addition to the open reduction and internal fixation., Open reduction and internal fixation - Mandible Fracture | Not applicable | Not yet recruiting | Cairo University | 20 | 2026-07-01 | 2026-06-29 |
| Clinical Outcomes of Transconjunctival Vs Transcutaneous Approaches in Orbital Fracture Repair orbital fracture reduction and fixation - Orbital Fractures | Not applicable | Recruiting | Alexandria University | 75 | 2026-05-25 | 2026-08-12 |
| 3D Custom Plate vs. Standard Titanium Plates for Mandibular Sub-condylar Fractures Fixation 3D custom plate, Standard titanium fixation plates - Mandibular Sub-condylar Fracture | Not applicable | Not yet recruiting | Esraa Mosad Tawfik | 30 | 2026-04-10 | 2026-03-19 |
| Comparison of Submucosal Dexamethasone and Methylprednisolone in Postoperative Sequelae of Parasymphsis Fractures Dexamethasone, Methylprednisolone (Corticosteroid) - Mandible Fracture, Edema Face | Phase 2 | Recruiting | Nishtar Medical University | 72 | 2026-01-03 | 2026-04-06 |
| Inter Flex Three Dimensional Plate in Management of Mandibular Fracture RCT Group I :site with mandibular fracture will be treated with custom made Inter-flex three dimensional plate in site of mandibular fracture - Mandibular Fracture Treatment | Not applicable | Recruiting | Suez Canal University | 20 | 2026-01-01 | 2026-01-22 |
| Skull Fractures in Pediatric Emergency Department: the Ultrasound Protocol Skull ultrasound - Skull Fractures | Not applicable | Recruiting | Istituto Giannina Gaslini | 150 | 2026-01-01 | 2026-06-09 |
| Accuracy of Positioning Guide and Customized Plate in Zygomaticomaxillary Complex Fractures Patient-specific positioning guide, Customized titanium plate - Zygomaticomaxillary Complex Fracture, Zygoma Fracture | Not applicable | Enrolling by invitation | Cairo University | 8 | 2025-11-01 | 2026-05-27 |
| Z-Shaped Versus Conventional Miniplates for Mandibular Fractures Z-shaped titanium miniplate, Conventional titanium miniplates - Mandibular Fractures | Not applicable | Completed | Sana'a University | 20 | 2025-09-25 | 2026-10-28 |
| Erich Arch Bars, IMF Screws and Hybrid Arch Bars in the Management of Mandibular Fractures Erich Arch Bars, Hybrid Arch Bars, IMF Screws - Mandibular Fractures | Not applicable | Recruiting | Mansoura University | 105 | 2025-09-16 | 2026-09-10 |
| Sagittal Split Plate Versus Two Miniplates in the Treatment of Mandibular Angle Fractures single Sagittal Split plate, two conventional miniplates - Mandible Fracture | Not applicable | Recruiting | Alexandria University | 16 | 2025-07-16 | 2025-08-05 |
| Multi-Institutional IMPACT Validation IMPACT-G Module, IMPACT-N Module, IMPACT-O Module - Facial Injuries, Mandible Fracture | Enrolling by invitation | University of Tennessee | 500 | 2025-07-01 | 2025-06-18 | |
| Evaluation of Pin Buckle Bone Plates for Management of Anterior Mandibular Fractures Pin Buckle Bone Plate, Conventional Titanium Miniplates - Mandibular Fractures, Symphysis Fractures | Not applicable | Completed | Suez Canal University | 20 | 2025-06-11 | 2026-07-30 |
| Comparing Pre-adaptation of In-stock Mesh Over In-house 3D Patient Specific Model to Reconstruct Unilateral Primary Orbital Fracture With and Without Intraoperative Navigation vs Conventional Intraoperative Free-hand Mesh Bending 3D printed patient specific model, Conventional, Brainlab navigation system - Orbital Fractures, Unilateral | Not applicable | Recruiting | Ain Shams University | 30 | 2025-06-01 | 2026-10-20 |
| BoneTape Feasibility Trial BoneTape - Zygomaticomaxillary Complex Fracture, Zygomatic Fractures | Not applicable | Recruiting | Cohesys Inc. | 30 | 2025-05-05 | 2025-08-22 |
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Mandibular Fractures (80) · Orbital Fractures (29) · Zygomatic Fractures (17) · Fractures, Bone (7) · Maxillary Fractures (7) · Wounds and Injuries (6) · Jaw Fractures (5) · Surgical Wound Infection (4) · Facial Injuries (3) · Intracranial Hemorrhages (3) · Maxillofacial Injuries (3) · Surgical Wound (3) · Wound Infection (3) · Agnosia (2)
Nervous System Diseases (135) · Trauma, Nervous System (135) · Craniocerebral Trauma (134) · Wounds and Injuries (129) · Fractures, Bone (128) · Facial Injuries (122) · Maxillofacial Injuries (122) · Jaw Fractures (82) · Pathological Conditions, Signs and Symptoms (15) · Pathologic Processes (12) · Eye Diseases (9) · Stomatognathic Diseases (8) · Infections (6) · Musculoskeletal Diseases (6)
Fracture Fixation, Internal (9) · Open Fracture Reduction (7) · Control Groups (3) · Amoxicillin-Potassium Clavulanate Combination (2) · Mandibular Reconstruction (2) · Surgery, Computer-Assisted (2) · Surgical Procedures, Operative (2) · Transplantation, Autologous (2) · Adrenal Cortex Hormones (1) · Amoxicillin (1) · Ascorbic Acid (1) · Bone Plates (1) · Bupivacaine (1) · Chitosan (1) · Clindamycin (1)
Cairo University (24) · Alexandria University (8) · Hams Hamed Abdelrahman (5) · Stryker Craniomaxillofacial (4) · Suez Canal University (4) · Tanta University (4) · Assiut University (3) · Fayoum University (3) · Instituto Mexicano del Seguro Social (3) · Mansoura University (3) · AO Clinical Investigation and Publishing Documentation (2) · AO Innovation Translation Center (2) · Ain Shams University (2) · Dufresne, Craig, MD, PC (2) · Emory University (2)
Egypt (52) · United States (22) · Germany (6) · Pakistan (6) · Switzerland (6) · France (4) · China (3) · Mexico (3) · Romania (3) · South Africa (3) · Spain (3) · United Kingdom (3) · Canada (2) · Finland (2) · Malaysia (2)
Craig R Dufresne, MD (2) · Olivier Lieger, MD, DMD (2) · Tateyuki Iizuka, MD, DDS, PhD (2) · Abdulaziz M Alanazi (1) · Ahmed Abdelmohsen Younis, Associate Professor (1) · Ahmed Mohamed, PhD (1) · Alaa Othman, PhD (1) · Alejandro Gonzalez Ojeda, M.D., Ph.D. (1) · Alejandro Gonzalez-Ojeda, PhD (1) · Alexey Yu Drobyshev, MD, PhD, DSc (1) · Alman Khan, BDS,FCPS (1) · Amr A. Gomaa, associate professor (1) · Andrew C Laing, PhD (1)
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