5 completed, 1 active not recruiting, 1 terminated, 1 unknown. 8 Phase 2, 3 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 5, Active not recruiting 1, Terminated 1, Unknown 1 |
| Phase 1 | 3 | Completed 2, Terminated 1 |
| Phase 3 | 2 | Completed 2 |
Follow Short Stature: new trials by email Literature Review of Short Stature trials Research Report on Short Stature
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vosoritide for Short Stature in Turner Syndrome Vosoritide - Turner Syndrome, Short Stature | Phase 2 | Unknown | Roopa Kanakatti Shankar, MBBS, MS | 20 | 2024-04-12 | 2024-06-24 |
| Vosoritide for Selected Genetic Causes of Short Stature Vosoritide - Short Stature | Phase 2 | Active not recruiting | Andrew Dauber | 56 | 2020-08-04 | 2026-03-18 |
| Growth Hormone Treatment in Patients With Aggrecan (ACAN) Deficiency Norditropin - Short Stature | Phase 1 / Phase 2 | Completed | Children's Hospital Medical Center, Cincinnati | 22 | 2018-02-01 | 2024-07-30 |
| IGF-1 Treatment for Individuals With Short Stature Due to PAPP-A2 Deficiency Increlex - Short Stature | Phase 1 / Phase 2 | Completed | Children's Hospital Medical Center, Cincinnati | 7 | 2015-12-21 | 2024-02-28 |
| Free Fatty Acids, Body Weight, and Growth Hormones Secretion in Children Niacin First, Placebo First, Dose-Establishing Study 1 Niacin 250mg - Obesity, Short Stature | Phase 1 / Phase 2 | Terminated | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 37 | 2011-07-01 | 2018-12-17 |
| Role of Nutrition and Hormones in Boys With Disordered Growth Growth Hormone Therapy - Short Stature, Constitutional Delay of Growth and Development | Phase 2 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 20 | 2005-01-19 | 2017-07-02 |
| Individualizing Dose of Growth Hormone to Maintain Normal Growth Velocity After Fulfilled Catch up Growth in Children Genotropin - Short Stature | Phase 2 / Phase 3 | Completed | Göteborg University | 99 | 2003-12-01 | 2019-04-30 |
| Weekly Zinc Chelate Supplementation on Children's Growth Zinc amino acid chelate, Placebo - Short Stature | Phase 2 / Phase 3 | Completed | Federal University of São Paulo | 199 | 2000-09-01 | 2013-12-24 |
Dwarfism (8) · Dwarfism, Pituitary (2) · Hypochondroplasia (1) · Noonan Syndrome (1) · Obesity (1) · Overweight (1) · Turner Syndrome (1)
Bone Diseases (8) · Bone Diseases, Developmental (8) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (8) · Endocrine System Diseases (8) · Genetic Diseases, Inborn (8) · Musculoskeletal Diseases (8) · Bone Diseases, Endocrine (2) · Brain Diseases (2) · Cardiovascular Abnormalities (2) · Cardiovascular Diseases (2) · Central Nervous System Diseases (2) · Congenital Abnormalities (2) · Heart Defects, Congenital (2) · Heart Diseases (2) · Hypopituitarism (2)
Human Growth Hormone (2) · vosoritide (2) · mecasermin (1)
Children's Hospital Medical Center, Cincinnati (2) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2) · Andrew Dauber (1) · Federal University of São Paulo (1) · Göteborg University (1) · Roopa Kanakatti Shankar, MBBS, MS (1)
United States (5)
Philippe Backeljauw, MD (2) · Andrew Dauber, MS MMSc (1) · Gajanathan Muthuvel, MD (1) · Jack A Yanovski, M.D. (1) · Kerstin Albertsson-Wikland, MD, prof (1) · Maria Halldin, MD (1) · Roopa Kanakatti Shankar, MBBS, MS (1) · Sten Ivarsson, MD, Prof (1)
PMID 19001519, PMID 20961566, PMID 29029190, PMID 30339244, PMID 34922359, PMID 35001504, PMID 36646053, PMID 36994923, PMID 38813446, PMID 39906034