5 completed. 5 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 5 |
Follow GLA-AF adjuvant: new trials by email Literature Review of GLA-AF adjuvant trials Research Report on GLA-AF adjuvant
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase Ib Study of the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel)(R) With or Without AP 10-701 for Intestinal Schistosomiasis in Healthy Exposed Adults GLA-AF, Hepatitis B Virus Vaccine (Recombinant), Sm-TSP-2/Alhydrogel - Schistosomiasis | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 60 | 2018-05-20 | 2021-02-02 |
| Safety and Immunogenicity of the Na-APR-1 Hookworm Vaccine in Healthy Adults Na-APR-1 (M74)/Alhydrogel®, Gluco-Pyranosylphospho-Lipid A Aqueous Formulation - Hookworm Infection, Hookworm Disease | Phase 1 | Completed | Baylor College of Medicine | 40 | 2013-09-01 | 2019-07-31 |
| Investigating Immunisation Strategies of DNA, MVA and CN54rgp140 Adjuvanted With GLA-AF to Maximise Antibody Responses DNA, MVA-C, CN54rgp140 - HIV | Phase 1 | Completed | Imperial College London | 40 | 2013-06-01 | 2016-09-27 |
| The Effects of GLA (5 mcg) on Human Volunteers GLA-AF, GLA-SE, EM060G (SE) - Healthy Volunteers | Phase 1 | Completed | Access to Advanced Health Institute (AAHI) | 17 | 2012-09-01 | 2014-02-26 |
| The Effects of GLA on Human Volunteers GLA-AF, GLA-SE, Squalene - Healthy Volunteers | Phase 1 | Completed | Rockefeller University | 32 | 2011-07-01 | 2013-09-23 |
Ancylostomiasis (1) · Anemia, Iron-Deficiency (1) · Hookworm Infections (1) · Neglected Diseases (1) · Schistosomiasis (1)
Access to Advanced Health Institute (AAHI) (1) · Baylor College of Medicine (1) · Imperial College London (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Rockefeller University (1)
United States (3) · Brazil (1) · United Kingdom (1)
David J Diemert, MD (1) · Franco Piazza, MD, MPH (1) · Marina Caskey, MD (1) · Sheena McCormack, MSc, FRCP (1)