53 unknown. 53 Phase 2, 22 Phase 1, 12 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 53 | Unknown 53 |
| Phase 1 | 22 | Unknown 22 |
| Phase 3 | 12 | Unknown 12 |
Follow Retinal Degeneration: new trials by email Literature Review of Retinal Degeneration trials Research Report on Retinal Degeneration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Therapeutic Efficacy of Faricimab for Clinical AMD, DME, and RVO Patients Faricimab - Age-Related Macular Degeneration, Diabetic Macular Edema | Phase 2 / Phase 3 | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 30 | 2024-03-01 | 2024-08-27 |
| Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration VOY-101 - Age-related Macular Degeneration, Geographic Atrophy | Phase 1 / Phase 2 | Unknown | Perceive Biotherapeutics, Inc. | 45 | 2022-11-17 | 2024-04-11 |
| A Study to Investigate the Effect on Central Macular Thickness of Treatment With MG-O-1002 Eye Drops in Participants Aged Over 45 With Neovascular Age-related Macular Degeneration (nAMD) MG-O-1002, Placebo - Age-Related Macular Degeneration | Phase 2 | Unknown | Theratocular Biotek Co. | 36 | 2022-08-09 | 2024-03-13 |
| The Effect of Stem Cells and Stem Cell Exosomes on Visual Functions in Patients With Retinitis Pigmentosa Subtenon injection of Wharton jelly derived mesenchymal stem cells, Subtenon injection of Wharton jelly derived mesenchymal stem cell exosomes, Placebo - Retinitis Pigmentosa | Phase 2 / Phase 3 | Unknown | TC Erciyes University | 135 | 2022-08-05 | 2022-09-07 |
| Results of Suprachoroidal Steroids Injections in Two Chorioretinal Diseases Triamcinolone Acetonide - Central Serous Chorioretinopathy, Irvine-Gass Syndrome | Phase 2 / Phase 3 | Unknown | Benha University | 50 | 2022-04-14 | 2022-04-20 |
| Comparison of Combined Intravitreal Bevacizumab and Oral Acetazolamide Versus Intravitreal Bevacizumab Alone for the Treatment of Macular Edema Secondary to Retinal Vein Occlusions intravitreal injection of bevacizumab with acetazolamide tablets, intravitreal injection of bevacizumab - Macular Edema | Phase 2 | Unknown | Shahid Beheshti University of Medical Sciences | 57 | 2022-03-12 | 2022-03-22 |
| Treatment of Age-related Macular Degeneration Using Retinal Stem and Progenitor Cells Cultured retinal stem and progenitor cells, Standard treatment according to the clinical protocols - Age-Related Macular Degeneration | Phase 1 / Phase 2 | Unknown | Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | 20 | 2022-03-01 | 2022-09-14 |
| Efficacy and Safety of Intravitreal Injection of Bevacizumab with and Without Oral Curcumin bevacizumab with oral curcumin, bevacizumab with oral placebo - Diabetic Macular Edema, Macular Edema | Phase 2 / Phase 3 | Unknown | Isfahan University of Medical Sciences | 52 | 2021-10-10 | 2024-09-19 |
| Effects of Treatment With N- Acetylcysteine on Visual Outcomes in Patients With Retinitis Pigmentosa Prescribe N-acetylcysteine tablets, Prescribe placebo tablets - Retinitis Pigmentosa | Phase 2 | Unknown | Shahid Beheshti University of Medical Sciences | 30 | 2021-04-17 | 2021-04-29 |
| An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene. sepofarsen - Leber Congenital Amaurosis 10, Blindness | Phase 2 / Phase 3 | Unknown | ProQR Therapeutics | 15 | 2021-03-23 | 2022-03-25 |
| Investigation of Therapeutic Efficacy and Safety of UMSCs for the Management of Retinitis Pigmentosa (RP) Injection of stem cells in sub-tenon space of eye for the management of retinitis pigmentosa, Injection of stem cells in suprachoroidal space of eye for the management of Retinitis Pigmentosa - Retinitis Pigmentosa (RP) | Phase 2 | Unknown | Jinnah Burn and Reconstructive Surgery Centre, Lahore | 50 | 2021-02-01 | 2021-02-21 |
| Single Ascending Dose Study in Participants With LCA10 EDIT-101 - Leber Congenital Amaurosis 10, Inherited Retinal Dystrophies | Phase 1 / Phase 2 | Unknown | Editas Medicine, Inc. | 34 | 2019-09-26 | 2022-12-05 |
| Minocycline Treatment for Cystoid Macular Edema minocycline - Minocycline, Cystoid Macular Edema | Phase 1 / Phase 2 | Unknown | Sun Yat-sen University | 5 | 2019-01-01 | 2023-04-19 |
| Safety and Tolerability of Oral CM082 in Patients With wAMD CM082 - Age-Related Macular Degeneration | Phase 2 | Unknown | AnewPharma | 64 | 2018-11-22 | 2020-01-13 |
| Comparison of Treatment Response to Intravitreal Injection of Combined Propranolol and Bevacizumab Versus Bevacizumab Monotherapy in Patients With Wet Age Related Macular Degeneration :A Clinical Trial Combined Intravitreal bevacizumab and propranolol, Intravitreal bevacizumab - Age Related Macular Degeneration | Phase 2 / Phase 3 | Unknown | Shahid Beheshti University of Medical Sciences | 40 | 2018-09-01 | 2018-08-01 |
| Studying a Potential Protective Effect of L-Dopa on Retinitis Pigmentosa levodopa-carbidopa - Retinitis Pigmentosa | Phase 2 | Unknown | Beirut Eye Specialist Hospital | 50 | 2016-06-01 | 2016-07-19 |
| Study of Subretinal Implantation of Human Embryonic Stem Cell-Derived RPE Cells in Advanced Dry AMD CPCB-RPE1 - Dry Macular Degeneration, Geographic Atrophy | Phase 1 / Phase 2 | Unknown | Regenerative Patch Technologies, LLC | 16 | 2016-02-16 | 2020-05-29 |
| Safety and Tolerability of hRPC in Retinitis Pigmentosa hRPC - Retinitis Pigmentosa | Phase 1 / Phase 2 | Unknown | ReNeuron Limited | 29 | 2015-12-01 | 2023-07-06 |
| Evaluating RXI-109 to Reduce the Progression of Subretinal Fibrosis in Subjects With NVAMD RXI-109 - Age-related Macular Degeneration, Subfoveal Choroidal Neovascularization | Phase 1 / Phase 2 | Unknown | RXi Pharmaceuticals, Corp. | 9 | 2015-11-01 | 2018-02-26 |
| Analysis of Aqueous and Vitreous Humor Ranibizumab, No Ranibizumab - Proliferative Diabetic Retinopathy, Macular Degeneration | Phase 2 | Unknown | California Retina Consultants | 45 | 2015-07-01 | 2017-03-01 |
Showing 20 of 53. Sign in to see all of them.
Macular Degeneration (28) · Macular Edema (13) · Retinitis Pigmentosa (9) · Retinal Diseases (5) · Diabetic Retinopathy (4) · Retinal Vein Occlusion (4) · Eye Diseases (3) · Geographic Atrophy (3) · Vision Disorders (3) · Choroidal Neovascularization (2) · Diabetes Mellitus (2) · Eye Abnormalities (2) · Genetic Diseases, Inborn (2) · Leber Congenital Amaurosis (2)
Eye Diseases (50) · Retinal Diseases (48) · Eye Diseases, Hereditary (14) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (13) · Macular Degeneration (13) · Genetic Diseases, Inborn (10) · Retinal Dystrophies (10) · Cardiovascular Diseases (7) · Pathological Conditions, Signs and Symptoms (7) · Vascular Diseases (7) · Endocrine System Diseases (6) · Nervous System Diseases (5) · Diabetes Complications (4) · Diabetes Mellitus (4)
Ranibizumab (8) · Bevacizumab (7) · Triamcinolone Acetonide (5) · aflibercept (2) · Acetazolamide (1) · Antioxidants (1) · Cholesterol (1) · Control Groups (1) · Curcumin (1) · Eggs (1) · Fluocinolone Acetonide (1) · Glatiramer Acetate (1) · Infliximab (1) · Lipectomy (1) · Lutein (1)
Shahid Beheshti University of Medical Sciences (3) · Catholic University of the Sacred Heart (2) · Rafic Hariri University Hospital (2) · Sun Yat-sen University (2) · University of Sao Paulo (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Al-Azhar University (1) · AnewPharma (1) · Beirut Eye Specialist Hospital (1) · Benha University (1) · California Retina Consultants (1) · Canadian Retinal Trials Group (1) · Central Clinical Hospital w/Outpatient Health Center of Business Administration for the President of Russian Federation (1) · Chaitanya Hospital, Pune (1) · Control Delivery Systems (1)
United States (14) · China (6) · Brazil (5) · Iran (4) · Israel (4) · United Kingdom (4) · Canada (3) · Italy (3) · Egypt (2) · Lebanon (2) · Netherlands (2) · Belarus (1) · Belgium (1) · Germany (1) · Hungary (1)
Ahmad M Mansour, MD (1) · Ahmad Mansour, MD (1) · Ahmed A Abdelshafy, MD (1) · Alina K Drakon, MD (1) · Avila Marcos, MD (1) · Ayala Pollack, MD (1) · Benedetto Falsini, M.D. (1) · Benedetto Falsini, MD (1) · Chenjin Jin, ph.D. (1) · David A Maberley, M.D. (1) · Elias F. Jarade, MD (1) · Elizeu Ramos, M.S. (1) · Ellen R Elias, MD (1) · Farzin Forooghian, MD (1)
PMID 19748675, PMID 20688744, PMID 23795985, PMID 25677668, PMID 27030277, PMID 28614154, PMID 31618812, PMID 31956432, PMID 32539744, PMID 32573764, PMID 33497524, PMID 34629400, PMID 36739258, PMID 36912792, PMID 37702300, PMID 38709228, PMID 40020685