2 active not recruiting, 2 recruiting, 1 completed, 1 withdrawn. 4 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Active not recruiting 1, Completed 1, Recruiting 1, Withdrawn 1 |
| Phase 2 | 3 | Recruiting 2, Active not recruiting 1 |
Follow Refractory Pancreatic Carcinoma: new trials by email Literature Review of Refractory Pancreatic Carcinoma trials Research Report on Refractory Pancreatic Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors Biospecimen Collection, Computed Tomography, Devimistat - Advanced Biliary Tract Carcinoma, Advanced Colorectal Carcinoma | Phase 2 | Recruiting | Northwestern University | 94 | 2023-03-08 | 2023-03-10 |
| Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors BET Bromodomain Inhibitor ZEN-3694, Computed Tomography, Core Biopsy - Advanced Malignant Solid Neoplasm, Locally Advanced Pancreatic Carcinoma | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 49 | 2022-11-16 | 2026-07-15 |
| Testing a New Anti-cancer Drug Combination, Entinostat and GSK525762C, for Advanced and Refractory Solid Tumors and Lymphomas Entinostat, Molibresib - Advanced Lymphoma, Advanced Malignant Solid Neoplasm | Phase 1 | Withdrawn | National Cancer Institute (NCI) | 2020-09-18 | 2020-09-28 | |
| A Phase I Study of SOR-C13 in Patients With Advanced Solid Tumors TRPV6 Calcium Channel Inhibitor SOR-C13 - Advanced Malignant Solid Neoplasm, Refractory Malignant Solid Neoplasm | Phase 1 | Completed | M.D. Anderson Cancer Center | 11 | 2019-07-29 | 2023-11-18 |
| Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer Danvatirsen, Durvalumab - Advanced Colorectal Carcinoma, Advanced Lung Non-Small Cell Carcinoma | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 39 | 2017-03-02 | 2025-05-06 |
| M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery Berzosertib, Biopsy Specimen, Biospecimen Collection - Metastatic Colorectal Carcinoma, Metastatic Lung Small Cell Carcinoma | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 66 | 2016-07-22 | 2026-09-25 |
Pancreatic Neoplasms (6) · Colorectal Neoplasms (3) · Lung Neoplasms (3) · Ovarian Neoplasms (2) · Adenocarcinoma of Lung (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Transitional Cell (1) · Lymphoma (1) · Lymphoma, B-Cell (1) · Lymphoma, T-Cell (1) · Neoplasm Metastasis (1) · Prostatic Neoplasms (1) · Small Cell Lung Carcinoma (1) · Turcot syndrome (1)
Digestive System Diseases (6) · Digestive System Neoplasms (6) · Endocrine Gland Neoplasms (6) · Endocrine System Diseases (6) · Neoplasms (6) · Neoplasms by Site (6) · Pancreatic Diseases (6) · Colonic Diseases (3) · Gastrointestinal Diseases (3) · Gastrointestinal Neoplasms (3) · Intestinal Diseases (3) · Intestinal Neoplasms (3) · Lung Diseases (3) · Rectal Diseases (3) · Respiratory Tract Diseases (3)
Specimen Handling (2) · entinostat (2) · Biopsy, Large-Core Needle (1) · Biopsy, Needle (1) · Disulfides (1) · Fluorouracil (1) · Gemcitabine (1) · Hydroxychloroquine (1) · Immunoglobulin G (1) · Irinotecan (1) · Magnetic Resonance Spectroscopy (1) · SOR-C13 (1) · berzosertib (1) · danvatirsen (1) · dehydroftorafur (1)
National Cancer Institute (NCI) (3) · M.D. Anderson Cancer Center (2) · Northwestern University (1)
United States (5)
Patricia M LoRusso (2) · David S Hong (1) · Devalingam Mahalingam (1) · Liza C Villaruz (1) · Siqing Fu (1)
UM1CA186689 (3), P30CA060553 (1), UM1CA186690 (1), UM1CA186704 (1), UM1CA186717 (1)