3 completed, 2 not yet recruiting, 2 recruiting. 4 Not applicable, 2 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Not yet recruiting 2, Completed 1, Recruiting 1 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Refractory Migraine: new trials by email Literature Review of Refractory Migraine trials Research Report on Refractory Migraine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| EMBRACE Study: Enduring Migraine Benefit From Responsive Artery Coil Embolization TEMMA Endovascular Treatment - Migraine Disorders, Refractory Migraine | Not applicable | Not yet recruiting | Cortex Neurovascular | 25 | 2028-03-01 | 2026-10-20 |
| Localized Injection of Lidocaine Via the Middle Meningeal Artery for Headache Treatment Lidocaine (drug), Saline - Refractory Migraine, Headache | Phase 2 | Recruiting | Daniel A Tonetti, MD | 80 | 2026-09-09 | 2026-10-01 |
| Bilateral Embolization of the Middle Meningeal Arteries for Refractory Chronic Migraine embolization of middle meningeal arteries - Migraine, Chronic Migraine Headache | Not applicable | Recruiting | Johns Hopkins University | 13 | 2026-04-24 | 2026-09-03 |
| Occipital Nerve Stimulation in Chronic Migraine Prodigy internal pulse generator occipital nerve stimulator - Chronic Migraine, Headache, Refractory Migraine | Not applicable | Not yet recruiting | University College, London | 40 | 2025-09-01 | 2025-07-28 |
| Localized Injection of Lidocaine and Glucocorticoid for Headache Treatment Phase 1 Lidocaine hydrochloride, Methylprednisolone sodium succinate - Refractory Migraine | Phase 1 | Completed | The Cooper Health System | 10 | 2024-03-15 | 2025-11-04 |
| Pulsed Electromagnetic Field Therapy in the Refractory Migraine pulsed electromagnetic field - Refractory Migraine | Not applicable | Completed | Niyayesh Clinic | 30 | 2012-01-01 | 2016-02-17 |
| Investigation of Efficacy and Safety of Botulinum Toxin A (Botox-Allergan Inc) in Migraine Headaches Botox, Placebo - Refractory Migraine | Phase 2 / Phase 3 | Completed | Yale University | 25 | 2008-01-01 | 2016-03-14 |
Migraine Disorders (7) · Headache (3) · Pain (1)
Brain Diseases (7) · Central Nervous System Diseases (7) · Headache Disorders (7) · Headache Disorders, Primary (7) · Nervous System Diseases (7) · Neurologic Manifestations (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Pain (3)
Lidocaine (2) · Sodium Chloride (2) · Botulinum Toxins, Type A (1) · Fluid Therapy (1) · Methylprednisolone (1) · Methylprednisolone Hemisuccinate (1) · Pharmaceutical Preparations (1)
Cortex Neurovascular (1) · Daniel A Tonetti, MD (1) · Johns Hopkins University (1) · Niyayesh Clinic (1) · The Cooper Health System (1) · University College, London (1) · Yale University (1)
United States (5) · Iran (1)
Bahman Jabbari, M.D. (1) · Boshra Hatef, Phd student PT,TMU (1) · Daniel A Tonetti, MD (1) · Dennis Wang, MD (1) · Hamza A Shaikh, MD (1) · Manisha Koneru, MD (1) · Risheng Xu, MD, PhD (1)