2 active not recruiting, 1 completed, 1 terminated. 4 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Active not recruiting 2, Completed 1, Terminated 1 |
| Phase 3 | 1 | Active not recruiting 1 |
Follow Refractory Malignant Neoplasm: new trials by email Literature Review of Refractory Malignant Neoplasm trials Research Report on Refractory Malignant Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated Cancers DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine MEDI0457, Durvalumab - Human Papillomavirus-16 Positive, Human Papillomavirus-18 Positive | Phase 2 | Terminated | M.D. Anderson Cancer Center | 41 | 2018-11-14 | 2024-07-09 |
| Cobimetinib and Atezolizumab in Treating Participants With Advanced or Refractory Rare Tumors Atezolizumab, Cobimetinib - Skin Squamous Cell Carcinoma, Appendix Adenocarcinoma | Phase 2 | Completed | M.D. Anderson Cancer Center | 49 | 2017-04-07 | 2025-05-28 |
| Physical Activity and Dexamethasone in Reducing Cancer-Related Fatigue in Patients With Advanced Cancer Dexamethasone, Exercise Intervention, Laboratory Biomarker Analysis - Advanced Malignant Neoplasm, Fatigue | Phase 2 / Phase 3 | Active not recruiting | M.D. Anderson Cancer Center | 90 | 2015-08-13 | 2026-09-22 |
| Talazoparib in Treating Patients With Recurrent, Refractory, Advanced, or Metastatic Cancers and Alterations in the BRCA Genes Laboratory Biomarker Analysis, Pharmacological Study, Talazoparib - Advanced Malignant Neoplasm, ATM Gene Mutation | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 150 | 2014-12-22 | 2026-06-12 |
Neoplasm Metastasis (4) · Neoplasms (4) · Recurrence (3) · Adenocarcinoma, Mucinous (1) · Anal Canal Carcinoma (1) · Anus Neoplasms (1) · Fatigue (1) · Penile Neoplasms (1) · Uterine Cervical Neoplasms (1) · Vaginal Neoplasms (1) · Vulvar Neoplasms (1)
Neoplastic Processes (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Disease Attributes (3) · Adenocarcinoma (1) · Anus Diseases (1) · Carcinoma (1) · Colorectal Neoplasms (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Gastrointestinal Diseases (1) · Gastrointestinal Neoplasms (1) · Genital Diseases (1)
Calcium Dobesilate (1) · Dexamethasone (1) · Disulfides (1) · Immunoglobulin G (1) · MEDI0457 (1) · VGX-3100 (1) · atezolizumab (1) · auricularum (1) · cobimetinib (1) · dexamethasone 21-phosphate (1) · dexamethasone acetate (1) · durvalumab (1) · rocakinogene sifuplasmid (1) · talazoparib (1)
M.D. Anderson Cancer Center (4)
United States (4)
Kanwal P Raghav (1) · Michael M Frumovitz (1) · Sarina A Piha-Paul (1) · Sriram Yennu (1)