87 completed, 34 active not recruiting, 32 terminated, 29 recruiting. 108 Phase 2, 65 Phase 1, 42 Phase 3, 15 Not applicable, 9 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Investigational Medication Combination of Daratumumab and Teclistamab Compared to the Usual Treatment (Daratumumab, Pomalidomide, Dexamethasone or Daratumumab, Carfilzomib, Dexamethasone) for Patients With High-risk Multiple Myeloma Refractory or in First Relapse Biospecimen Collection, Bone Marrow Biopsy, Carfilzomib - Recurrent Multiple Myeloma, Refractory Multiple Myeloma | Phase 2 | Recruiting | National Cancer Institute (NCI) | 80 | 2027-05-22 | 2026-10-20 |
| Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM Trial Autologous Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Bone Marrow Aspiration - Plasma Cell Leukemia | Phase 2 | Recruiting | National Cancer Institute (NCI) | 74 | 2027-04-20 | 2026-10-07 |
| Testing the Investigational Medication Combination of Teclistamab and Pomalidomide Compared to the Usual Treatment (Carfilzomib, Pomalidomide, and Dexamethasone) for Patients With Multiple Myeloma Who Have Relapsed Shortly After Treatment Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Recurrent Multiple Myeloma, Refractory Multiple Myeloma | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 162 | 2027-04-12 | 2026-10-16 |
| FPS-ZM1 With or Without Dexamethasone for Controlling Post Operative Cerebral Edema in Patients With Glioblastoma Biospecimen Collection, Computed Tomography, Dexamethasone - Glioblastoma, Malignant Glioma | Phase 1 | Not yet recruiting | City of Hope Medical Center | 24 | 2027-02-17 | 2026-08-27 |
| Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate Cancer Abiraterone Acetate, Biospecimen Collection, Bone Scan - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 / Phase 3 | Not yet recruiting | ECOG-ACRIN Cancer Research Group | 432 | 2027-01-06 | 2026-10-01 |
| Testing the Addition of an Anti-Cancer Drug, Glofitamab, to the Usual Chemotherapy Treatment (Alternating R-CHOP/R-DHAP) for Previously Untreated Mantle Cell Lymphoma Biospecimen Collection, Cisplatin, Computed Tomography - Ann Arbor Stage II Mantle Cell Lymphoma, Ann Arbor Stage III Mantle Cell Lymphoma | Phase 1 | Not yet recruiting | National Cancer Institute (NCI) | 16 | 2026-10-30 | 2026-09-03 |
| Testing Blinatumomab With or Without Revumenib in Patients With B-cell Acute Lymphoblastic Leukemia With a Genetic Change Requiring More Treatment Biospecimen Collection, Blinatumomab, Bone Marrow Aspiration - Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic Leukemia | Phase 2 | Not yet recruiting | SWOG Cancer Research Network | 90 | 2026-10-14 | 2026-10-13 |
| Time to First Rescue Antiemetic With Ondansetron Plus Metoclopramide Versus Dexamethasone Plus Metoclopramide for PONV Prophylaxis in Laparoscopic Cholecystectomy ondansetron 4 mg, Dexamethasone (intravenous), Metoclopramide 10mg - Postoperative Nausea and Vomiting | Phase 4 | Recruiting | Faisalabad Medical University | 264 | 2026-09-01 | 2026-09-04 |
| Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL) Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration - Stage II T Lymphoblastic Leukemia/Lymphoma, Stage III T Lymphoblastic Leukemia/Lymphoma | Phase 2 / Phase 3 | Not yet recruiting | Children's Oncology Group | 1708 | 2026-08-28 | 2026-07-30 |
| Selvigaltin With Standard of Care Treatment for the Treatment of Relapsed/Refractory Multiple Myeloma Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Recurrent Multiple Myeloma, Refractory Multiple Myeloma | Phase 1 | Withdrawn | Roswell Park Cancer Institute | 2026-04-01 | 2026-05-15 | |
| The Efficacy and Safety of Fosrolapitant and Palonosetron Hydrochloride for Injection in Preventing Nausea and Vomiting Caused by Multi-cycle Immunotherapy and Chemotherapy in Patients With Esophageal Cancer and Lung Cancer Fosrolapitant and Palonosetron Hydrochloride for Injection combined with dexamethasone acetate, For injection, fosapirtan dimeglumine combined with palonosetron hydrochloride and dexamethasone acetate - Esophagus Cancer, Lung Cancer | Phase 2 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 120 | 2025-11-01 | 2026-06-01 |
| Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma Asparaginase Erwinia chrysanthemi, Biospecimen Collection, Bone Marrow Aspiration - B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative, Lymphoblastic Lymphoma | Phase 2 | Recruiting | City of Hope Medical Center | 53 | 2025-10-10 | 2026-10-13 |
| Evaluating Premedication Regimens (Methylprednisolone vs Dexamethasone-based) for the Prevention of Systemic and Injection Site Reactions to Motixafortide in Patients With Multiple Myeloma Undergoing Stem Cell Mobilization, PARADE Trial Acetaminophen, Biospecimen Collection, Dexamethasone - Multiple Myeloma | Phase 4 | Recruiting | Emory University | 94 | 2025-09-24 | 2026-07-23 |
| A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015) Opevesostat, Fludrocortisone/ Fludrocortisone acetate, Dexamethasone/Dexamethasone acetate - Malignant Neoplasm | Phase 2 | Recruiting | Merck Sharp & Dohme LLC | 250 | 2025-08-11 | 2026-10-06 |
| Epcoritamab Plus Standard of Care Platinum-Based Chemotherapy and Autologous Hematopoietic Cell Transplant for the Treatment of Relapsed or Refractory Large B-cell Lymphoma Autologous Hematopoietic Stem Cell Transplantation, Carboplatin, Cytarabine - Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Phase 2 | Recruiting | University of California, Davis | 25 | 2025-07-31 | 2026-06-30 |
| Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia Asparaginase Erwinia chrysanthemi, Biospecimen Collection, Blinatumomab - Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic Leukemia | Phase 2 | Recruiting | National Cancer Institute (NCI) | 153 | 2025-06-05 | 2026-10-21 |
| Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial) Biospecimen Collection, Cemiplimab, Computed Tomography - Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8 | Phase 2 / Phase 3 | Recruiting | SWOG Cancer Research Network | 378 | 2025-05-22 | 2026-10-09 |
| Mezigdomide, Carfilzomib, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma in Patients With Extramedullary Disease Mezigdomide, Carfilzomib, Dexamethasone - Extramedullary Disease in Multiple Myeloma, Recurrent Multiple Myeloma | Phase 2 | Recruiting | Roswell Park Cancer Institute | 28 | 2025-05-01 | 2026-08-18 |
| Elotuzumab, Daratumumab, Iberdomide, and Dexamethasone for the Treatment of Relapsed Multiple Myeloma Bone Marrow Aspiration, Bone Marrow Biopsy, Bone Scan - Recurrent Multiple Myeloma | Phase 1 / Phase 2 | Recruiting | Mayo Clinic | 37 | 2025-03-18 | 2026-06-25 |
| Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial Biospecimen Collection, Computed Tomography, Dexamethasone - Low Grade Glioma, Malignant Brain Glioma | Phase 2 | Recruiting | Emory University | 200 | 2025-01-09 | 2026-02-10 |
Showing 20 of 214. Sign in to see all of them.
Multiple Myeloma (74) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (28) · Burkitt Lymphoma (26) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (12) · Immunoglobulin Light-chain Amyloidosis (8) · Leukemia, Biphenotypic, Acute (8) · Recurrence (8) · Lymphoma, Mantle-Cell (7) · Nausea (7) · Vomiting (7) · Lymphoma (6) · Lymphoma, Large B-Cell, Diffuse (6) · Hodgkin Disease (5) · Leukemia (5) · Leukemia, Myeloid, Acute (5)
M.D. Anderson Cancer Center (34) · National Cancer Institute (NCI) (31) · Mayo Clinic (26) · Children's Oncology Group (11) · SWOG Cancer Research Network (8) · City of Hope Medical Center (7) · Emory University (7) · Barbara Ann Karmanos Cancer Institute (6) · ECOG-ACRIN Cancer Research Group (4) · OHSU Knight Cancer Institute (4) · Roswell Park Cancer Institute (4) · Merck Sharp & Dohme LLC (3) · University of Southern California (3) · University of Washington (3) · Abdullah Khan (2)
United States (168) · Canada (23) · Australia (18) · Puerto Rico (18) · New Zealand (14) · Switzerland (9) · Austria (6) · Germany (6) · China (5) · France (5) · Israel (5) · Spain (5) · Brazil (4) · Italy (4) · Belgium (3)
Elias Jabbour (7) · Shaji Kumar (5) · Shaji Kumar, M.D. (4) · Farhad Ravandi-Kashani (3) · Sikander Ailawadhi, M.D. (3) · Abdullah M Khan, MBBS, MSc (2) · Anne L Angiolillo (2) · Ibrahim Aldoss (2) · Jana L Portnow (2) · Jeffrey A. Zonder, MD (2) · Michael A Rosenzweig (2) · Saroj Vadhan-Raj, MD (2) · Shaji K Kumar (2)
PMID 35622074, PMID 37890117, PMID 39121442, PMID 41671463, PMID 26590194, PMID 29284596, PMID 36603187, PMID 38446568, PMID 39321347, PMID 40315406, PMID 42085640, PMID 10048682, PMID 11773155, PMID 11815760, PMID 12562658, PMID 14757603, PMID 17015575, PMID 1731020, PMID 18595987, PMID 19181644, PMID 19853510, PMID 20100768, PMID 20113991, PMID 20466853, PMID 21817948, PMID 21860025, PMID 22487117, PMID 22627678, PMID 22689675, PMID 22734014, PMID 23233571, PMID 23422747, PMID 23678006, PMID 23799873, PMID 24586581, PMID 24668858, PMID 24825530, PMID 24885354, PMID 24970932, PMID 25311218, PMID 25649543, PMID 25964296, PMID 26071868, PMID 26124497, PMID 26265699, PMID 26432046, PMID 26943915, PMID 26945843, PMID 27381904, PMID 27658581
U10CA180886 (16), U10CA098543 (13), U10CA180820 (11), U10CA180888 (11), P30CA015083 (10), P30CA138292 (7), P30CA022453 (6), P30CA016672 (5), P30CA033572 (5), U10CA021115 (4), U10CA032102 (4), P30CA014089 (3), P30CA069533 (3), 2017 (2), P30CA015704 (2)