12 unknown, 10 completed, 6 not yet recruiting, 4 recruiting. 16 Not applicable, 4 Phase 2, 2 Phase 4, 1 Early Phase 1, 1 Phase 3.
Follow Recurrent Implantation Failure: new trials by email Literature Review of Recurrent Implantation Failure trials Research Report on Recurrent Implantation Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Endometrial Immune Profile in Recurrent Implantation Failure Recurrent Implantation Failure, Infertility (IVF Patients) | Not yet recruiting | King's College London | 64 | 2026-10-01 | 2026-09-30 | |
| ERA in Young Primary Infertile RIF Patients tb-ERA and personalized embryo transfer - Recurrent Implantation Failure | Not yet recruiting | ShangHai Ji Ai Genetics & IVF Institute | 400 | 2026-08-15 | 2026-08-17 | |
| Zishen Yutai Pill for Patients With Recurrent Implantation Failure Zishen Yutai Pill, Placebo - Recurrent Implantation Failure | Not applicable | Not yet recruiting | Peking University Third Hospital | 878 | 2026-07-01 | 2026-06-11 |
| Experimental Study on the Use of Intrauterine Infusion of Autologous Platelet-rich Plasma (PRGF-IUI) in Patients With Recurrent Implantation Failure and/or Refractory Thin Endometrium Intrauterine Platelet-Rich Plasma (PRP) Infusion, Hormone Replacement Therapy (HRT) - Recurrent Implantation Failure, Endometrial Receptivity Disorders | Not applicable | Not yet recruiting | Azienda Sanitaria Locale di Asti | 80 | 2026-05-01 | 2026-05-14 |
| Study of Endometrial Immune and Microbiological Modifications in Cases of Recurrent Implantation Failure and/or Recurrent Pregnancy Loss Endometrial Biopsy, Vaginal Swab, Blood sample - Recurrent Implantation Failure, Recurrent Pregnancy Loss | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 100 | 2026-04-01 | 2026-02-05 |
| Efficacy of a Non-Invasive Endometrial Receptivity Prediction Model Based on Peripheral Blood miRNA Signatures During the Peri-Implantation Period in Improving IVF Outcomes in Patients With Unexplained RIF Non-invasive endometrial receptivity prediction model guides personalized embryo transfer for patients with recurrent implantation failure (RIF). - Recurrent Implantation Failure | Not applicable | Not yet recruiting | Tang-Du Hospital | 546 | 2026-02-01 | 2026-01-23 |
| Comparing FET Guided by ERA Vs Standard Timing in Patients with Recurrent Implantation Failure Frozen embryo transfer according to endometrial receptivity analysis result - Recurrent Implantation Failure, Infertility | Not applicable | Recruiting | The University of Hong Kong | 734 | 2025-02-15 | 2025-03-26 |
| Bone Marrow Derived Stem Cells Mobilization for Treatment of Abnormal Endometrium Plerixafor - Asherman Syndrome, Atrophic Endometrium | Early Phase 1 | Recruiting | Hugh Taylor | 90 | 2023-11-01 | 2025-11-12 |
| Effect of Hysteroscopic Metroplasty on Reproductive Outcome in Patients with RIF Hysterocopic metroplasty - Recurrent Implantation Failure, T-Shaped Uterus | Not applicable | Enrolling by invitation | Shanghai First Maternity and Infant Hospital | 200 | 2022-01-01 | 2025-02-26 |
| Effect of Acupuncture on the Clinical Outcome of IVF-ET in Patients With Recurrent Implantation Failure acupuncture - Acupuncture, Recurrent Implantation Failure | Not applicable | Unknown | ShangHai Ji Ai Genetics & IVF Institute | 310 | 2021-05-01 | 2021-08-10 |
| Effect of Low Molecular Weight Heparin in Freeze-thaw Embryo Transfer Cycles in Women With Recurrent Implantation Failure Low Molecular Weight Heparine - Low Molecular Weight Heparin, Recurrent Implantation Failure | Completed | The Second Hospital of Shandong University | 392 | 2021-01-01 | 2025-08-12 | |
| Short Course Rifapentine and Isoniazid for the Preventive Treatment for Latent Genital Tuberculosis rifapentine plus isoniazid - Infertility, Female, Recurrent Implantation Failure | Phase 3 | Unknown | Huashan Hospital | 1050 | 2020-09-01 | 2020-08-27 |
| Effect of Reproductive Tract Microbiota on Pregnancy Outcome in IVF/ICSI Infertility, Recurrent Implantation Failure | Unknown | Peking University Third Hospital | 120 | 2020-08-18 | 2021-02-02 | |
| Role of Atosiban in Recurrent Implantation Failure Recurrent Implantation Failure | Unknown | Al Baraka Fertility Hospital | 150 | 2019-10-10 | 2021-09-28 | |
| Intrauterine Infusion of GCSF and Reproductive Outcomes in Infertile Women with History of RIF Granulocyte Colony-Stimulating Factor, placebo - Recurrent Implantation Failure, Granulocyte Colony-Stimulating Factor | Completed | Cairo University | 100 | 2019-09-01 | 2024-10-01 | |
| Preimplantation Genetic Testing for Aneuploidies in Patients With Recurrent Implantation Failure PGT-A, Control - Recurrent Implantation Failure | Not applicable | Recruiting | Universitaire Ziekenhuizen KU Leuven | 100 | 2019-05-01 | 2025-02-26 |
| Use of Metabolomics for the Identification of Endometrial Biomarkers for IRPL and RIF After in Vitro Fertilization metabolomics analysis - Recurrent Pregnancy Loss, Recurrent Implantation Failure | Not applicable | Unknown | University Hospital, Angers | 40 | 2019-01-01 | 2018-10-01 |
| The PIP Study - Pre- IVF Immune Profiling Study Sub-fertility, Recurrent Implantation Failure | Unknown | University of Oxford | 250 | 2018-09-26 | 2018-10-29 | |
| Effect of Granulocyte Colony-stimulating Factor on Clinical Pregnancy Rate in Patients With Endometriosis Granulocyte Colony-Stimulating Factor, Intrauterine infusion of normal saline - Recurrent Implantation Failure, Endometriosis | Phase 2 | Unknown | Amira Magdi Guergues Selim | 88 | 2018-06-01 | 2018-06-08 |
| Azathioprine in Recurrent Implantation Failure Azathioprine Pill, Placebo Oral Tablet - Recurrent Implantation Failure, In Vitro Fertilization | Phase 2 | Completed | Ain Shams University | 64 | 2018-04-25 | 2019-07-24 |
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Infertility (11) · Infertility, Female (4) · Abortion, Habitual (3) · Abortion, Spontaneous (2) · Adenomyosis (2) · Endometriosis (2) · Dysmenorrhea (1) · Endometritis (1) · Gynatresia (1) · Mannose-Binding Protein Deficiency (1) · Tuberculosis, Female Genital (1) · Uterine Diseases (1)
Genital Diseases (17) · Urogenital Diseases (17) · Female Urogenital Diseases and Pregnancy Complications (9) · Female Urogenital Diseases (7) · Genital Diseases, Female (7) · Infertility (3) · Pregnancy Complications (3) · Abortion, Spontaneous (1) · Actinomycetales Infections (1) · Adnexal Diseases (1) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1) · Gram-Positive Bacterial Infections (1) · Infections (1) · Menstruation Disturbances (1)
Filgrastim (2) · Granulocyte Colony-Stimulating Factor (2) · Heparin, Low-Molecular-Weight (2) · Acupuncture Therapy (1) · Aromatase (1) · Aromatase Inhibitors (1) · Aspirin (1) · Azathioprine (1) · Blood Specimen Collection (1) · Control Groups (1) · Crinone (1) · Gels (1) · Gonadotropin-Releasing Hormone (1) · Hormone Replacement Therapy (1) · Immunoglobulins, Intravenous (1)
Centre for Endocrinology and Reproductive Medicine, Italy (2) · Peking University Third Hospital (2) · ShangHai Ji Ai Genetics & IVF Institute (2) · Shanghai First Maternity and Infant Hospital (2) · Aalborg University Hospital (1) · Acibadem University (1) · Ain Shams University (1) · Al Baraka Fertility Hospital (1) · Amira Magdi Guergues Selim (1) · Assistance Publique - Hôpitaux de Paris (1) · Azienda Sanitaria Locale di Asti (1) · Cairo University (1) · Dr. Kamal Rageh (1) · Huashan Hospital (1) · Hugh Taylor (1)
China (9) · Iran (4) · Bahrain (2) · Egypt (2) · France (2) · Italy (2) · Turkey (Türkiye) (2) · United Kingdom (2) · Albania (1) · Belgium (1) · Bulgaria (1) · Denmark (1) · Israel (1) · United States (1)
Mohammad Nouri, Ph.D (3) · Mehdi Yousefi, Ph.D (2) · Ahmed H Salama (1) · Cumhur B Urman, M.D. (1) · Daniela A Marconi, MD (1) · Ernest HY Ng, MD (1) · Hugh Taylor, MD (1) · Ingrid Granne, DPhil MA MBBS MRCOG (1) · Ippokratis Sarris, DM, FRCOG (1) · Lu Li, M.Sc. (1) · Mathilde Bourdon, MD, PhD (1) · Mehdi Yousefi, Immunologist (1)
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