6 not yet recruiting, 4 completed, 3 recruiting, 2 active not recruiting. 11 Not applicable, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Not yet recruiting 5, Active not recruiting 2, Recruiting 2, Enrolling by invitation 1, Unknown 1 |
| Phase 3 | 3 | Completed 2, Recruiting 1 |
Follow Rectal Cancer Surgery: new trials by email Literature Review of Rectal Cancer Surgery trials Research Report on Rectal Cancer Surgery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| FLuorescent Angiography in REduction of Anastomotic Leak in Rectal Cancer Surgery Indocyanine Green Fluorescence Angiography, Standard Surgical Perfusion Assessment - Rectal Cancer Patients, Rectal Cancer Surgery | Not applicable | Not yet recruiting | Basavatarakam Indo American Cancer Hospital & Research Institute | 610 | 2026-11-15 | 2026-10-27 |
| ColoSeal™ ICD System Anastomotic Protection Pivotal Study ColoSeal ICD System, Protective Diverting Ostomy - Rectal Cancer Surgery | Not applicable | Active not recruiting | Averto Medical, Inc. | 250 | 2026-06-19 | 2026-10-13 |
| REsults of LOw Anterior Resections With or Without Preventive Stoma in Nonemergency Department Without a preventive stoma, With a preventive stoma - TME, Rectal Cancer Surgery | Not applicable | Recruiting | ANO Scientific and Practical Club for the Development of Modern Medical Technologies | 442 | 2026-05-05 | 2026-05-13 |
| Postoperative Outcomes of Single-stapled Anastomosis Combined With Transanal Natural Orifice Specimen Extraction Rectal Cancer Patients, Rectal Cancer Surgery | Not yet recruiting | Istituto Clinico Humanitas | 190 | 2026-01-31 | 2026-01-22 | |
| The SMART Trial: Modified Single-Stapled Anastomosis in Laparoscopic or Robotic Low Anterior Resection for Rectal Cancer Modified single-stapled anastomosis technique - Rectal Neoplasms, Rectal Neoplasms Malignant | Not applicable | Enrolling by invitation | Korea University Anam Hospital | 450 | 2025-12-20 | 2026-01-29 |
| Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance Intensified follow-up program - LARS - Low Anterior Resection Syndrome, Rectal Cancer Surgery | Phase 3 | Recruiting | University Hospital, Basel, Switzerland | 140 | 2025-12-01 | 2026-05-06 |
| Comparison of Different Surgical Approaches in Female Rectal Cancer. Surgical approach - Rectal Cancer Surgery | Not applicable | Not yet recruiting | First Affiliated Hospital of Wenzhou Medical University | 200 | 2025-10-01 | 2025-09-24 |
| Walking and Sitting Difficulties After Rectal Cancer Surgery Targeted leaderled training program, Control arm with WHO recommendation on physical activity - Rectal Cancer Patients, Rectal Cancer Surgery | Not applicable | Not yet recruiting | Sahlgrenska University Hospital | 300 | 2025-09-15 | 2025-06-25 |
| Intraoperative Rectal Lavage to Prevent Local Recurrence After Laparoscopic Mid-to-Low Rectal Cancer Resection: A Multicenter Randomized Trial Rectal irrigation - Middle and Low Rectal Cancer, Rectal Cancer Surgery | Not applicable | Recruiting | Sun Yat-sen University | 1598 | 2025-06-01 | 2026-04-06 |
| Pelvic Floor Peritoneal Closure to Prevent Postoperative Ileus in Mid-Low Rectal Cancer Surgery Pelvic floor peritoneum reconstruction - Rectal Cancer Surgery, Middle and Low Rectal Cancer | Not applicable | Active not recruiting | Sun Yat-sen University | 516 | 2025-06-01 | 2026-02-25 |
| Effect of Preserving the Left Colic Artery on Proximal Bowel Perfusion High Tie of Inferior Mesenteric Artery, Low Tie of Inferior Mesenteric Artery - Rectal Cancer Surgery, Perfusion Imaging | Not applicable | Not yet recruiting | Ningbo Medical Center Lihuili Hospital | 143 | 2025-06-01 | 2025-05-21 |
| Impact of IMA Occlusion on Anastomotic Leakage Rectal Cancer Surgery, Anastomotic Leak Rectum | Completed | Istanbul Saglik Bilimleri University | 123 | 2025-05-01 | 2026-06-18 | |
| Transanal Irrigation for Low Anterior Resection Syndrome Transanal Irrigation (TAI) - Low Anterior Resection Syndrome, Rectal Cancer Surgery | Not applicable | Not yet recruiting | Seoul National University Hospital | 94 | 2025-02-01 | 2025-01-28 |
| Indocyanine Green Fluorescence Angiography in Laparoscopic Sigmoid and Rectal Cancer Surgery Colorectal Cancer (CRC), Rectal Cancer Surgery | Completed | Jagiellonian University | 115 | 2023-10-09 | 2026-02-20 | |
| Applications of Fluorescence Imaging Guided Lymph Node Dissection and Fluorescence Angiography of Inferior Mesenteric Artery Assisted Left Colic Artery Preservation Fluorescence laparoscopic system - Fluorescence, Indocyanine Green | Not applicable | Unknown | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 100 | 2023-05-01 | 2023-09-13 |
| Mechanical Bowel Preparation and Oral Antibiotics Before Rectal Cancer Surgery Sennosides colonic preparation, Oral Gentamycin, Oral Ornidazole - Rectal Cancer Surgery | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 414 | 2018-09-03 | 2024-01-05 |
| Drainage After Rectal Excision for Rectal Cancer Laying and management of the drain (strictly randomized arm with drainage), No pelvic drainage - Rectal Cancer Surgery, Randomized Clinical Trial | Phase 3 | Completed | University Hospital, Bordeaux | 494 | 2011-01-01 | 2026-05-14 |
Rectal Neoplasms (8) · Anastomotic Leak (5) · Colorectal Neoplasms (3) · Low Anterior Resection Syndrome (2) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Gastrointestinal Diseases (1) · Gastrointestinal Neoplasms (1) · Ileus (1) · Intestinal Diseases (1) · Intestinal Neoplasms (1) · Intestinal Obstruction (1) · Neoplasms by Site (1) · Rectal Diseases (1) · Sigmoid Neoplasms (1)
Digestive System Diseases (11) · Gastrointestinal Diseases (11) · Intestinal Diseases (11) · Neoplasms (11) · Rectal Diseases (11) · Digestive System Neoplasms (10) · Gastrointestinal Neoplasms (10) · Intestinal Neoplasms (10) · Neoplasms by Site (10) · Colorectal Neoplasms (8) · Pathologic Processes (8) · Pathological Conditions, Signs and Symptoms (8) · Postoperative Complications (8) · Colonic Diseases (5) · Colonic Neoplasms (1)
Drainage (1) · Gentamicins (1) · Ornidazole (1) · Oviposition (1)
Sun Yat-sen University (2) · ANO Scientific and Practical Club for the Development of Modern Medical Technologies (1) · Assistance Publique - Hôpitaux de Paris (1) · Averto Medical, Inc. (1) · Basavatarakam Indo American Cancer Hospital & Research Institute (1) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · First Affiliated Hospital of Wenzhou Medical University (1) · Istanbul Saglik Bilimleri University (1) · Istituto Clinico Humanitas (1) · Jagiellonian University (1) · Korea University Anam Hospital (1) · Ningbo Medical Center Lihuili Hospital (1) · Sahlgrenska University Hospital (1) · Seoul National University Hospital (1) · University Hospital, Basel, Switzerland (1)
China (3) · France (2) · South Korea (2) · India (1) · Italy (1) · New Zealand (1) · Poland (1) · Russia (1) · Sweden (1) · Switzerland (1) · Turkey (Türkiye) (1) · United States (1)
Anna Gawlicka, PhD, MBA (1) · Antonino Spinelli, MD, PhD (1) · Charlotta E Larsson, MD, PhD (1) · Daniel Steinemann, Deputy chief physician (1) · Jiazi Yu, M.D. (1) · Jin Kim, M.D., Ph.D (1) · Syed Nusrath, MS,DNB(Gen Surg),DNB(Surg Onc) (1)
PMID 27631776, PMID 30255647, PMID 36748942, PMID 42428782, PMID 42767745
R44CA287615 (1)