14 completed, 5 unknown, 1 active not recruiting, 1 recruiting. 21 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 21 | Completed 14, Unknown 5, Active not recruiting 1, Recruiting 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
Follow Prolapse: new trials by email Literature Review of Prolapse trials Research Report on Prolapse
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vaginal Estrogen for Improvement of Outcomes Following Pelvic Organ Prolapse Surgery Vaginal Estrogen - Twice Weekly, Vaginal Estrogen - Daily - Pelvic Organ Prolapse (POP) | Phase 3 | Recruiting | Sarah Wozney | 180 | 2026-01-01 | 2026-08-20 |
| Effect of Local Estriol Treatment Before Vaginal Repair Surgery estriol cream - Pelvic Organ Prolapse, Pelvic Floor Disorders | Phase 3 | Active not recruiting | Hatice Tukenmez Kurnaz | 36 | 2024-04-01 | 2025-02-05 |
| Gamma-irradiated Amniotic Membrane Graft in Posterior Colporrhaphy posterior colporrhaphy using gamma-irradiated amniotic membrane as a graft - Rectocele; Female, Pelvic Organ Prolapse | Phase 3 | Completed | Ain Shams Maternity Hospital | 25 | 2023-11-01 | 2025-12-02 |
| Lidocaine for Pessary Check Pain Reduction Lidocaine Hcl 2% Jelly, Placebo Jelly - Pelvic Organ Prolapse, Stress Urinary Incontinence | Phase 3 | Completed | University of South Florida | 66 | 2022-09-08 | 2023-12-14 |
| Alfacalcidol Supplementation on Levator Ani Muscle Strength of Menopausal Pelvic Organ Prolapse Patients Alfacalcidol 0.0005 MG, Placebo - Pelvic Organ Prolapse | Phase 3 | Completed | Universitas Padjadjaran | 48 | 2020-11-01 | 2022-08-17 |
| Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures Vaginal scrub, to be applied vaginally and perineally immediately prior to surgery. - Pelvic Organ Prolapse, Urinary Incontinence | Phase 3 | Completed | University of New Mexico | 137 | 2019-07-15 | 2023-07-10 |
| Tamsulosin vs Placebo to Prevent Postoperative Urinary Retention in Female Pelvic Reconstructive Surgery Placebo oral capsule, Tamsulosin - Urinary Retention, Lower Urinary Tract Symptoms | Phase 2 / Phase 3 | Completed | University Hospitals Cleveland Medical Center | 132 | 2018-08-01 | 2021-11-08 |
| Does Intravenous Tranexamic Acid Reduce Blood Loss During Vaginectomy? Tranexamic Acid Injectable Solution, Placebo - Pelvic Organ Prolapse | Phase 3 | Unknown | Mount Sinai Hospital, Canada | 30 | 2018-01-01 | 2022-04-06 |
| Anchor for Robotic Sacrocolpopexy Anchor, Suture - Pelvic Organ Prolapse | Phase 3 | Unknown | Kaiser Permanente | 53 | 2017-11-29 | 2019-03-06 |
| Gabapentin Reduces Opioid Use Postoperatively ("GROUP Study") Gabapentin, placebo - Pelvic Organ Prolapse | Phase 3 | Unknown | Mount Sinai Hospital, Canada | 44 | 2017-01-01 | 2017-02-14 |
| the Indications and Clinical Efficacy of Pelvic Organ Prolapse Surgery transvaginal synthetic mesh, Tolterodine - Pelvic Organ Prolapse | Phase 3 | Unknown | Peking University People's Hospital | 1000 | 2015-08-01 | 2017-05-23 |
| Effects of Preoperative Dexamethasone Study on QOL After Vaginal Reconstructive Surgery for POP Dexamethasone, Placebo - Pelvic Organ Prolapse, PONV | Phase 3 | Completed | TriHealth Inc. | 63 | 2013-02-01 | 2016-04-21 |
| Pelvic Organ Prolapse Repair Plus Mini-Sling Versus Pelvic Organ Prolapse Repair Alone POP repair plus mini-sling, POP repair - Pelvic Organ Prolapse, Urinary Incontinence | Phase 3 | Completed | University Of Perugia | 50 | 2011-06-01 | 2014-05-20 |
| Surgical Correction of Pelvic Organ Prolapse Colposacropexy - Pelvic Organ Prolapse | Phase 3 | Completed | University Of Perugia | 40 | 2010-08-01 | 2014-05-20 |
| The Effects of Local Vaginal Estrogen in Postmenopausal Women With Pelvic Organ Prolapse Vaginal conjugated estrogen cream 0.5gm, Vaginal conjugated estrogen cream 1.0gm - Pelvic Organ Prolapse, Vaginal Atrophy | Phase 3 | Completed | TriHealth Inc. | 54 | 2008-12-01 | 2015-05-27 |
| Post-Operative Pain Control Using Direct Continuous Bupivacaine Infusion After Pelvic Organ Prolapse Repair Continuous bupivacaine analgesia infusion (ON-Q PainBuster Post-Op Pain Relief System) - Post-Operative Pain, Pelvic Organ Prolapse | Phase 2 / Phase 3 | Unknown | St. Luke's Hospital, Kansas City, Missouri | 80 | 2007-04-01 | 2008-06-11 |
| Safety Study of Pelvic Organ Prolapse Repair Using Transvaginal Mesh Transvaginal mesh- PROLIFT®-system - Pelvic Organ Prolapse | Phase 2 / Phase 3 | Completed | Karolinska Institutet | 250 | 2006-08-01 | 2007-11-14 |
| Mesh Repair of Anterior Vaginal Wall Prolapse Low-weight prolypropylene mesh - Anterior Vaginal Wall Prolapse | Phase 3 | Completed | Tampere University | 202 | 2003-04-01 | 2007-01-11 |
| Pexy Versus Non-pexy for Full Thickness Rectal Prolapse sacral rectopexy with sutures or meshes, full rectal mobilization from the sacrum without sacral rectopexy - Rectal Prolapse | Phase 3 | Completed | Societa Italiana di Chirurgia ColoRettale | 180 | 2003-01-01 | 2009-12-02 |
| Colpopexy and Urinary Reduction Efforts (CARE) Protocol Burch urethropexy at time of sacrocolpopexy - Urinary Incontinence, Stress, Uterine Prolapse | Phase 3 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 322 | 2002-04-01 | 2011-01-11 |
Showing 20 of 21. Sign in to see all of them.
Pelvic Organ Prolapse (19) · Urinary Incontinence (4) · Urinary Incontinence, Stress (3) · Pelvic Floor Disorders (2) · Agnosia (1) · Atrophic Vaginitis (1) · Cystocele (1) · Genital Diseases, Female (1) · Lower Urinary Tract Symptoms (1) · Orgasm (1) · Pain, Postoperative (1) · Postoperative Nausea and Vomiting (1) · Rectal Prolapse (1) · Rectocele (1) · Recurrence (1)
Pathological Conditions, Anatomical (21) · Pathological Conditions, Signs and Symptoms (21) · Female Urogenital Diseases (9) · Female Urogenital Diseases and Pregnancy Complications (9) · Urogenital Diseases (9) · Male Urogenital Diseases (8) · Signs and Symptoms (8) · Urologic Diseases (7) · Urination Disorders (6) · Urological Manifestations (6) · Lower Urinary Tract Symptoms (5) · Pathologic Processes (4) · Genital Diseases (3) · Postoperative Complications (3)
Sutures (2) · Data Collection (1) · Dexamethasone (1) · Estrogens, Conjugated (USP) (1) · Gabapentin (1) · Gels (1) · Lidocaine (1) · Saline Solution (1) · Tamsulosin (1) · Tolterodine Tartrate (1) · Tranexamic Acid (1) · Vaginal Creams, Foams, and Jellies (1) · Videotape Recording (1) · alfacalcidol (1)
Mount Sinai Hospital, Canada (2) · TriHealth Inc. (2) · University Of Perugia (2) · Ain Shams Maternity Hospital (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Hatice Tukenmez Kurnaz (1) · Kaiser Permanente (1) · Karolinska Institutet (1) · Peking University People's Hospital (1) · Sarah Wozney (1) · Societa Italiana di Chirurgia ColoRettale (1) · St. Luke's Hospital, Kansas City, Missouri (1) · Tampere University (1) · Universitas Padjadjaran (1) · University Hospitals Cleveland Medical Center (1)
United States (10) · Canada (3) · Finland (2) · Italy (2) · China (1) · Denmark (1) · Egypt (1) · Indonesia (1) · Norway (1) · Sweden (1) · Turkey (Türkiye) (1)
Ahmed M Abbas, MD (1) · Alexander A Berger (1) · Araba A Jackson, MD (1) · Carolyn M Sampselle, PhD,RNC,FAAN (1) · Christine M Vaccaro, DO (1) · Colleen McDermott, MD (1) · Daniel Altman, MD, PhD (1) · Danny Lovatsis, MD (1) · Fulya Dokmeci (1) · Graham Chapman (1) · Ihab FS Eldin Allam, MD (1) · Jianliu Wang, professor (1) · Karen Taylor, BA (1) · Kari Nieminen (1) · Linda Brubaker, MD (1)
PMID 12790869, PMID 16282227, PMID 16611949, PMID 16897749, PMID 17336819, PMID 18060963, PMID 18060965, PMID 18074068, PMID 18185903, PMID 18455536, PMID 18591307, PMID 18656053, PMID 18716704, PMID 18722933, PMID 18845288, PMID 18976976, PMID 19104367, PMID 19104368, PMID 19701041, PMID 21344495, PMID 22517125, PMID 26032041, PMID 29564507, PMID 31039170, PMID 32413431, PMID 32769645, PMID 33894146, PMID 33935807, PMID 34973179, PMID 37431855, PMID 37888839
R01NR004007 (1), U10HD041248 (1), U10HD041250 (1), U10HD041261 (1), U10HD041263 (1), U10HD041267 (1), U10HD041268 (1), U10HD041269 (1)