3 completed, 2 terminated. 5 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 3, Terminated 2 |
| Phase 2 | 3 | Completed 3 |
Follow Progressive Supranuclear Palsy: new trials by email Literature Review of Progressive Supranuclear Palsy trials Research Report on Progressive Supranuclear Palsy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AMX0035 and Progressive Supranuclear Palsy AMX0035, Placebo - Progressive Supranuclear Palsy, PSP | Phase 2 / Phase 3 | Completed | Amylyx Pharmaceuticals Inc. | 139 | 2023-12-21 | 2026-04-30 |
| Study to Evaluate the Safety and Efficacy of Davunetide for the Treatment of Progressive Supranuclear Palsy Davunetide, Placebo - Progressive Supranuclear Palsy | Phase 2 / Phase 3 | Completed | Allon Therapeutics | 313 | 2010-10-01 | 2013-01-17 |
| Efficacy, Tolerability and Safety of Azilect in Subjects With Progressive Supranuclear Palsy Rasagiline, Sugar pill - Progressive Supranuclear Palsy | Phase 3 | Terminated | Prof. Dr. Stefan Lorenzl | 44 | 2010-01-01 | 2013-04-24 |
| Effects of Coenzyme Q10 in PSP and CBD CoQ10 - Progressive Supranuclear Palsy, Neurological Disorders | Phase 2 / Phase 3 | Completed | Lahey Clinic | 2004-01-01 | 2018-06-15 | |
| Neuroprotection and Natural History in Parkinson's Plus Syndromes (NNIPPS) Riluzole - Multiple System Atrophy, Progressive Supranuclear Palsy | Phase 3 | Terminated | King's College London | 800 | 2000-04-01 | 2005-12-15 |
Supranuclear Palsy, Progressive (5) · Multiple System Atrophy (1) · Nervous System Diseases (1) · Neurodegenerative Diseases (1)
Basal Ganglia Diseases (5) · Brain Diseases (5) · Central Nervous System Diseases (5) · Cranial Nerve Diseases (5) · Eye Diseases (5) · Movement Disorders (5) · Neurologic Manifestations (5) · Ocular Motility Disorders (5) · Ophthalmoplegia (5) · Paralysis (5) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (5) · Tauopathies (5) · Nervous System Diseases (4) · Neurodegenerative Diseases (4)
Riluzole (1) · Sugars (1) · coenzyme Q10 (1) · davunetide (1) · rasagiline (1) · sodium phenylbutyrate and taurursodiol (1)
Allon Therapeutics (1) · Amylyx Pharmaceuticals Inc. (1) · King's College London (1) · Lahey Clinic (1) · Prof. Dr. Stefan Lorenzl (1)
Germany (3) · United States (3) · France (2) · United Kingdom (2) · Australia (1) · Canada (1) · Italy (1) · Spain (1)
Adam Boxer, M.D., PhD. (1) · Diana Apetauerova, MD (1) · Peter N Leigh, PhD FRCP (1) · Stefan Lorenzl, PD Dr. (1)
PMID 19029129, PMID 19771175, PMID 21386111, PMID 21829612, PMID 24873720, PMID 28436538, PMID 38825840
2008 (1)