5 completed. 4 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 4 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow davunetide: new trials by email Literature Review of davunetide trials Research Report on davunetide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Evaluate the Safety and Efficacy of Davunetide for the Treatment of Progressive Supranuclear Palsy Davunetide, Placebo - Progressive Supranuclear Palsy | Phase 2 / Phase 3 | Completed | Allon Therapeutics | 313 | 2010-10-01 | 2013-01-17 |
| Davunetide (AL-108) in Predicted Tauopathies - Pilot Study davunetide (AL-108, NAP), Placebo nasal spray - Predicted Tauopathies, Including, Progressive Supranuclear Palsy | Phase 1 | Completed | University of California, San Francisco | 12 | 2010-01-01 | 2019-04-05 |
| A Multicenter Study of NAP (AL-108) in Schizophrenia AL-108, Placebo - Schizophrenia | Phase 2 | Completed | University of California, Los Angeles | 63 | 2007-07-01 | 2017-03-10 |
| Safety, Tolerability and Efficacy Study to Evaluate Subjects With Mild Cognitive Impairment AL-108, Placebo - Mild Cognitive Impairment, So Stated | Phase 2 | Completed | Allon Therapeutics | 144 | 2007-01-01 | 2012-10-24 |
| Study to Evaluate Safety, Tolerability, and Effect of AL208 on Mild Cognitive Impairment Following Coronary Artery Bypass Graft Surgery AL-208, Placebo - Mild Cognitive Impairment | Phase 2 | Completed | Allon Therapeutics | 234 | 2006-08-01 | 2012-10-24 |
Cognitive Dysfunction (2) · Supranuclear Palsy, Progressive (2) · Corticobasal Degeneration (1) · Dementia (1) · Frontotemporal Dementia (1) · Frontotemporal Lobar Degeneration (1) · Primary Progressive Nonfluent Aphasia (1) · Schizophrenia (1)
Allon Therapeutics (3) · University of California, Los Angeles (1) · University of California, San Francisco (1)
United States (5) · Canada (2) · Australia (1) · France (1) · Germany (1) · United Kingdom (1)
Adam Boxer, M.D., PhD. (1) · Adam L. Boxer, M.D., Ph.D. (1) · Daniel C Javitt, MD, PhD (1) · Donald E Schmechel, MD (1) · Elena Matthews, MD (1)
PMID 23594991, PMID 24873720, PMID 28433500, PMID 28436538, PMID 38825840, PMID 39358355, PMID 41173865