2 completed, 1 active not recruiting, 1 not yet recruiting, 1 unknown. 5 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 2, Active not recruiting 1, Not yet recruiting 1, Unknown 1 |
| Phase 1 | 2 | Active not recruiting 1, Not yet recruiting 1 |
Follow Prion Diseases: new trials by email Literature Review of Prion Diseases trials Research Report on Prion Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial of ALN-6457 in Adult Participants With Symptomatic Prion Disease (PrD) ALN-6457 - Prion Disease | Phase 1 / Phase 2 | Not yet recruiting | Regeneron Pharmaceuticals | 60 | 2026-10-23 | 2026-09-22 |
| PrProfile: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ION717 ION717, Placebo - Prion Disease | Phase 1 / Phase 2 | Active not recruiting | Ionis Pharmaceuticals, Inc. | 85 | 2024-01-04 | 2026-09-18 |
| Knee Arthritis Treatment With Autologous Fragmented Adipose Tissue and PRP - Comparison of Two Treatment Methods autologous adipose tissue transfer, PRP injections - Osteo Arthritis Knee, Knee Osteoarthritis | Phase 2 | Unknown | Rehasport Clinic | 60 | 2018-07-30 | 2020-03-25 |
| Familiar Fatal Insomnia: Preventive Treatment With Doxycycline in Subject With Disease Risk Doxycycline Hcl, Placebo - Familial Fatal Insomnia | Phase 2 | Completed | Mario Negri Institute for Pharmacological Research | 29 | 2011-04-28 | 2024-12-05 |
| CJD (Creutzfeldt-Jakob Disease) Quinacrine Study Quinacrine, Placebo - Creutzfeldt-Jakob Disease | Phase 2 | Completed | University of California, San Francisco | 69 | 2005-04-01 | 2014-06-09 |
Insomnia, Fatal Familial (4) · Creutzfeldt-Jakob Syndrome (2) · Dementia (2) · Arthritis (1) · Central Nervous System Diseases (1) · Central Nervous System Infections (1) · Gerstmann-Straussler-Scheinker Disease (1) · Joint Diseases (1) · Nervous System Diseases (1) · Neurodegenerative Diseases (1) · Osteoarthritis, Knee (1) · Proteostasis Deficiencies (1)
Infections (5) · Central Nervous System Diseases (4) · Central Nervous System Infections (4) · Dyssomnias (4) · Nervous System Diseases (4) · Neurodegenerative Diseases (4) · Sleep Disorders, Intrinsic (4) · Sleep Initiation and Maintenance Disorders (4) · Sleep Wake Disorders (4) · Brain Diseases (2) · Mental Disorders (2) · Neurocognitive Disorders (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Genetic Diseases, Inborn (1)
Quinacrine (1)
Ionis Pharmaceuticals, Inc. (1) · Mario Negri Institute for Pharmacological Research (1) · Regeneron Pharmaceuticals (1) · Rehasport Clinic (1) · University of California, San Francisco (1)
United States (2) · Australia (1) · Canada (1) · France (1) · Germany (1) · Israel (1) · Italy (1) · Japan (1) · Poland (1) · Spain (1)
Bruce L. Miller, MD (1) · Michael Geschwind, MD, PhD (1) · Pawel Bakowski, MD PhD (1) · Tomasz Piontek, MD PhD (1)
2023 (1), P01AG021601 (1)