4 completed, 1 recruiting, 1 terminated, 1 withdrawn. 5 Phase 2, 2 Phase 1, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 2, Recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 1 | 2 | Completed 1, Terminated 1 |
| Not applicable | 1 | Completed 1 |
Follow Quinacrine: new trials by email Literature Review of Quinacrine trials Research Report on Quinacrine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Quinacrine in Participants With Cutaneous Lupus Erythematosus Quinacrine Hydrochloride, Placebo - Cutaneous Lupus Erythematosus (CLE) | Phase 2 | Recruiting | Victoria Werth | 24 | 2026-06-30 | 2026-08-12 |
| Quinacrine-Capecitabine Combinatorial Therapy for Advanced Stage Colorectal Adenocarcinoma Quinacrine and Capecitabine - Colorectal Adenocarcinoma | Phase 1 / Phase 2 | Terminated | Fox Chase Cancer Center | 19 | 2016-01-14 | 2021-03-25 |
| Erlotinib Hydrochloride and Quinacrine Dihydrochloride in Stage IIIB-IV Non-Small Cell Lung Cancer erlotinib hydrochloride, quinacrine dihydrochloride - Escalation dose, laboratory biomarker analysis - Recurrent Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer | Phase 1 | Completed | Neelesh Sharma MD PhD | 12 | 2013-09-01 | 2016-10-31 |
| Treatment of Advanced Renal Cell Carcinoma With Quinacrine quinacrine - Renal Cell Carcinoma | Phase 2 | Withdrawn | Cleveland BioLabs | 2007-11-01 | 2015-08-03 | |
| Quinacrine Treatment in Patients With Androgen-Independent Prostate Cancer Quinacrine - Prostatic Cancer | Phase 2 | Completed | Cleveland BioLabs | 31 | 2006-12-01 | 2013-04-11 |
| CJD (Creutzfeldt-Jakob Disease) Quinacrine Study Quinacrine, Placebo - Creutzfeldt-Jakob Disease | Phase 2 | Completed | University of California, San Francisco | 69 | 2005-04-01 | 2014-06-09 |
| PRION-1: Quinacrine for Human Prion Disease Quinacrine - Prion Disease | Not applicable | Completed | Medical Research Council | 160 | 2004-06-01 | 2015-04-07 |
Creutzfeldt-Jakob Syndrome (2) · Prion Diseases (2) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Renal Cell (1) · Dementia (1) · Insomnia, Fatal Familial (1) · Lupus Erythematosus, Cutaneous (1) · Nervous System Diseases (1) · Prostatic Neoplasms (1)
Cleveland BioLabs (2) · Fox Chase Cancer Center (1) · Medical Research Council (1) · Neelesh Sharma MD PhD (1) · University of California, San Francisco (1) · Victoria Werth (1)
United States (5) · United Kingdom (1)
Bruce L. Miller, MD (1) · Crystal S. Denlinger, MD (1) · Edwin Posadas, MD (1) · Janet Darbyshire, MBChB, FRCP (1) · John Collinge, MD, FRCP (1) · John H Gordon, PhD (1) · Michael Geschwind, MD, PhD (1) · Neelesh Sharma, MD, PhD (1) · Victoria P Werth, MD (1)
P01AG021601 (1)