11 completed, 5 unknown, 3 active not recruiting, 3 recruiting. 7 Phase 3, 3 Phase 4, 2 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 5, Active not recruiting 2 |
| Phase 4 | 3 | Completed 1, Terminated 1, Unknown 1 |
| Not applicable | 2 | Unknown 2 |
| Phase 1 | 1 | Unknown 1 |
Follow Primary Immune Deficiency: new trials by email Literature Review of Primary Immune Deficiency trials Research Report on Primary Immune Deficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating Bronchodilator Response in Patients With Bronchiectasis spirometry, Salbutamol, placebo - Bronchiectasis, Cystic Fibrosis | Not applicable | Unknown | Rambam Health Care Campus | 96 | 2023-05-20 | 2023-07-06 |
| Evaluation of Adult Patients With Immunodeficiency Within the Scope of the ICF Primary Immune Deficiency, Exercise Capacity | Completed | Hacettepe University | 40 | 2023-03-15 | 2024-02-28 | |
| An Open Label, Multicenter Study to Evaluate the Pharmacokinetics, Efficacy and Safety of ASCENIV™ (IGIV) in Pediatric Subjects With Primary Immunodeficiency Diseases (PIDD) Asceniv™ - Primary Immune Deficiency | Phase 4 | Unknown | ADMA Biologics, Inc. | 12 | 2022-09-01 | 2022-09-16 |
| A Prospective Monocentric Study to Assess the Concordance of Lung MRI Compared to Chest CT Scan to Assess the Extent and Severity of Bronchial and Parenchymal Pulmonary Lesions in Adult Patients With Primary Immune Deficiency (PID) . MRI procedure - Primary Immune Deficiency | Not applicable | Unknown | Hopital Foch | 50 | 2021-11-03 | 2022-07-27 |
| COVID-19 Vaccine Responses in PIDD Subjects X-linked Agammaglobulinemia, XLA | Active not recruiting | Duke University | 100 | 2021-09-30 | 2025-06-03 | |
| Study to Evaluate the Pharmacokinetics, Efficacy, Tolerability, and Safety of Subcutaneous Human Immunoglobulin (Newnorm) in Patients With Primary Immunodeficiency Diseases Newnorm - Primary Immune Deficiency | Phase 3 | Active not recruiting | Octapharma | 50 | 2021-08-04 | 2026-08-06 |
| Characterizing the Upper Airway Manifestations in Primary Ciliary Dyskinesia and Primary Immunodeficiencies Primary Ciliary Dyskinesia, Kartagener Syndrome | Completed | University of North Carolina, Chapel Hill | 159 | 2021-06-09 | 2025-08-21 | |
| Biologics And Clinical Immunology Cohort at Sinai Immunological Disease, Autoimmune Diseases | Recruiting | Icahn School of Medicine at Mount Sinai | 800 | 2021-03-03 | 2026-02-17 | |
| Study of Immune Globulin Intravenous (Human) GC5107 in Pediatric Subjects With Primary Humoral Immunodeficiency GC5107 - Primary Immune Deficiency | Phase 3 | Active not recruiting | GC Biopharma Corp | 24 | 2020-12-21 | 2025-07-25 |
| Defining the Genetic Etiology of Suppurative Lung Disease in Children and Adults Genetic Testing for PCD or PID, Unaffected Family Member Genetic Testing - Primary Ciliary Dyskinesia, Primary Immune Deficiency | Completed | University of North Carolina, Chapel Hill | 436 | 2020-12-01 | 2025-08-21 | |
| Primitive Immunodeficiency and Pregnancy Questionnaire - Primary Immune Deficiency | Completed | Assistance Publique - Hôpitaux de Paris | 99 | 2020-11-30 | 2026-03-09 | |
| COVID-19 in PID Survey Primary Immune Deficiency, COVID | Recruiting | Imagine Institute | 200 | 2020-03-15 | 2026-09-10 | |
| Transfer of Effector Memory T Cells (Tem) Following Allogeneic Stem Cell Transplantation CD62L- Tem - Lymphoma, Leukemia | Phase 1 | Unknown | University College, London | 18 | 2019-10-21 | 2019-10-25 |
| Study of Immune Deficiency Patients Treated With Subcutaneous Immunoglobulin (IgPro20, Hizentra®) on Weekly and Biweekly Schedules Subcutaneous Immune Globulin (Human) (Hizentra) - Primary Immune Deficiency, Secondary Immune Deficiency | Phase 4 | Completed | CSL Behring | 26 | 2016-03-15 | 2018-02-26 |
| Determinants of Health Status and Quality of Life in Patients With Primary Immunodeficiencies Inhereted Diagnosed During Childhood Primary Immune Deficiency | Unknown | Assistance Publique Hopitaux De Marseille | 1780 | 2012-05-01 | 2016-08-16 | |
| Multicenter Study of Long-Term Clinical Outcomes of Subcutaneous Immune Globulin IgPro20 in Subjects With Primary Immunodeficiency (Japan Study) Immune globulin subcutaneous (Human) - Primary Immune Deficiency | Phase 3 | Completed | CSL Behring | 22 | 2011-10-01 | 2014-12-02 |
| Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy (Japan Study) Immune Globulin Subcutaneous (Human) (SCIG) - Primary Immune Deficiency | Phase 3 | Completed | CSL Behring | 25 | 2010-09-01 | 2014-12-12 |
| Retrospective Chart Review of Subcutaneous IgG Use in Infants Subcutaneous IgG (SCIG) - Primary Immune Deficiency | Completed | CSL Behring | 27 | 2010-05-01 | 2011-02-11 | |
| Extension Study of Subcutaneous Immunoglobulin Human in Patients With Primary Immunodeficiency (PID) IgPro20 - Primary Immune Deficiency | Phase 3 | Completed | CSL Behring | 21 | 2008-06-01 | 2014-04-02 |
| Safety Study of Subcutaneous Ig NextGen 16% in Patients With Primary Immunodeficiency Immunoglobulin G (Ig NextGen 16%) - Primary Immune Deficiency | Phase 3 | Completed | CSL Limited | 41 | 2008-04-01 | 2013-06-19 |
Showing 20 of 23. Sign in to see all of them.
Primary Immunodeficiency Diseases (23) · Ciliary Motility Disorders (3) · Autoimmune Diseases (2) · Kartagener Syndrome (2) · Anemia, Aplastic (1) · Asthma (1) · Bronchiectasis (1) · Bronchiolitis Obliterans (1) · Bruton type agammaglobulinemia (1) · COVID-19 (1) · Common Variable Immunodeficiency (1) · Cystic Fibrosis (1) · Genetic Diseases, Inborn (1) · Graft vs Host Disease (1) · Immune System Diseases (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (23) · Genetic Diseases, Inborn (22) · Immune System Diseases (22) · Immunologic Deficiency Syndromes (22) · Respiratory Tract Diseases (5) · Bronchial Diseases (4) · Abnormalities, Multiple (3) · Ciliopathies (3) · Congenital Abnormalities (3) · Lung Diseases (3) · Otorhinolaryngologic Diseases (3) · Bronchiectasis (2) · Cardiovascular Abnormalities (2) · Cardiovascular Diseases (2) · Dextrocardia (2)
Hizentra (5) · gamma-Globulins (4) · Immunoglobulin G (2) · Albuterol (1) · Apoptosis (1) · Bronchodilator Agents (1) · Fluid Therapy (1) · Genetic Testing (1) · Heptavalent Pneumococcal Conjugate Vaccine (1) · Pneumococcal Vaccines (1) · Proline (1) · Respiratory Function Tests (1) · Spirometry (1) · Surveys and Questionnaires (1) · Vivaglobin (1)
CSL Behring (6) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · University of North Carolina, Chapel Hill (2) · ADMA Biologics, Inc. (1) · Assistance Publique - Hôpitaux de Paris (1) · Assistance Publique Hopitaux De Marseille (1) · CSL Limited (1) · Duke University (1) · GC Biopharma Corp (1) · Hacettepe University (1) · Hopital Foch (1) · Icahn School of Medicine at Mount Sinai (1) · Imagine Institute (1) · Octapharma (1) · Rambam Health Care Campus (1)
United States (12) · France (4) · Canada (3) · Japan (2) · Turkey (Türkiye) (2) · Australia (1) · Bosnia and Herzegovina (1) · Germany (1) · Hungary (1) · Israel (1) · Italy (1) · New Zealand (1) · Poland (1) · Serbia (1) · Slovakia (1)
Caroline Charlier-Woerther, MD (1) · Ebru Calik-Kutukcu, PhD (1) · Elie Haddad, MD (1) · Elise Mallart (1) · Gulbu Uzel, M.D. (1) · Helen C Su, M.D. (1) · John Sleasman, MD (1) · Kenneth Olivier, MD, MPH (1) · Kristina De Paris, PhD (1) · Melvin Berger, MD, PhD (1) · Mordechai Pollak, MD, MSc (1) · Nizar Mahlaoui, MD (1)
PMID 20454851, PMID 21553933, PMID 24412910, PMID 24504846, PMID 29198545, PMID 29305315, PMID 37210041
U54HL096458 (2), 2015 (1), R21AI168980 (1)