6 completed. 6 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 6 |
| Phase 2 | 1 | Completed 1 |
Follow Primary Biliary Cirrhosis: new trials by email Literature Review of Primary Biliary Cirrhosis trials Research Report on Primary Biliary Cirrhosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis Fenofibrate, UDCA - Primary Biliary Cirrhosis | Phase 3 | Completed | Xijing Hospital of Digestive Diseases | 117 | 2016-04-08 | 2023-03-08 |
| Phase 3 Study of Obeticholic Acid in Patients With Primary Biliary Cirrhosis Obeticholic Acid (OCA), Placebo - Primary Biliary Cirrhosis | Phase 3 | Completed | Intercept Pharmaceuticals | 217 | 2012-01-01 | 2021-05-06 |
| Safety and Efficacy of Tauroursodeoxycholic Acid Versus Ursofalk in the Treatment of Adult Primary Biliary Cirrhosis Tauroursodeoxycholic Acid Capsules, Ursodeoxycholic Acid Capsules - Primary Biliary Cirrhosis | Phase 3 | Completed | Beijing Friendship Hospital | 216 | 2009-09-01 | 2013-05-20 |
| Study Comparing Tetrathiomolybdate vs Standard Treatment in Primary Biliary Cirrhosis Tetrathiomolybdate, Placebo - Primary Biliary Cirrhosis | Phase 3 | Completed | George Brewer | 29 | 2006-04-01 | 2017-05-23 |
| Safety and Efficacy of Long-Term Treatment With Atorvastatin in Patients With Primary Biliary Cirrhosis Atorvastatin - Primary Biliary Cirrhosis, Hypercholesterolemia | Phase 3 | Completed | Medical University of Graz | 40 | 2006-01-01 | 2009-02-16 |
| Study of Combivir for Patients With Primary Biliary Cirrhosis Combination antiviral therapy, Placebo - Primary Biliary Cirrhosis | Phase 2 / Phase 3 | Completed | University of Alberta | 59 | 2004-01-01 | 2007-11-01 |
Liver Cirrhosis, Biliary (6) · Atherosclerosis (1) · Cholestasis (1) · Fibrosis (1) · Hypercholesterolemia (1)
Bile Duct Diseases (6) · Biliary Tract Diseases (6) · Cholestasis, Intrahepatic (6) · Digestive System Diseases (6) · Liver Cirrhosis (6) · Liver Diseases (6) · Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6) · Cholestasis (5) · Fibrosis (5) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Cardiovascular Diseases (1) · Dyslipidemias (1) · Hyperlipidemias (1)
Atorvastatin (1) · Fenofibrate (1) · Ursodeoxycholic Acid (1) · lamivudine, zidovudine drug combination (1) · obeticholic acid (1) · tetrathiomolybdate (1) · ursodoxicoltaurine (1)
Beijing Friendship Hospital (1) · George Brewer (1) · Intercept Pharmaceuticals (1) · Medical University of Graz (1) · University of Alberta (1) · Xijing Hospital of Digestive Diseases (1)
United States (3) · Austria (2) · Canada (2) · China (2) · United Kingdom (2) · Australia (1) · Belgium (1) · France (1) · Germany (1) · Italy (1) · Netherlands (1) · Poland (1) · Spain (1) · Sweden (1)
Andrew L Mason, MBBS MRCPI (1) · Bruce Bacon, MD (1) · Catherine Vincent, MD FRCPC (1) · Christian Weyer, MD (1) · Dong Ji Jia, Doctor (1) · James Neuberger, MD FRCP (1) · Keith Lindor, MD (1) · Michael Trauner, M.D. (1)
PMID 19782361, PMID 25543678, PMID 27532829, PMID 30922873, PMID 31606455, PMID 33319187, PMID 36892506, PMID 42449190