6 completed. 6 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 6 |
| Phase 2 | 2 | Completed 2 |
Follow Primary Biliary Cirrhosis: new trials by email Literature Review of Primary Biliary Cirrhosis trials Research Report on Primary Biliary Cirrhosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Umbilical Cord Derived Mesenchymal Stem Cell (UC -MSC) Transplantation for Children Suffering From Biliary Atresia Umbilical Cord Derived Mesenchymal Stem Cell (UC -MSC) Transplantation - Primary Biliary Cirrhosis | Phase 1 / Phase 2 | Completed | Vinmec Research Institute of Stem Cell and Gene Technology | 20 | 2019-08-10 | 2024-06-06 |
| An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects 3 mg [14C]-A4250 capsule - Orphan Cholestatic Liver Diseases, Progressive Familial Intrahepatic Cholestasis | Phase 1 | Completed | Albireo | 6 | 2017-01-31 | 2024-03-07 |
| A Safety and Pharmakokinetic Study of A4250 Alone or in Combination With A3384 A4250, CRC (A3384), Questran - Orphan Cholestatic Liver Diseases, Primary Biliary Cirrhosis | Phase 1 | Completed | Albireo | 94 | 2013-07-01 | 2024-03-07 |
| Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CT 11C-CSar, ICG - Cholestasis, Primary Sclerosing Cholangitis | Phase 1 | Completed | University of Aarhus | 22 | 2013-06-01 | 2015-02-23 |
| Modafinil in the Treatment of Fatigue in Patients With Primary Biliary Cirrhosis (PBC) Modafinil - Fatigue, Primary Biliary Cirrhosis | Phase 1 | Completed | Mayo Clinic | 40 | 2009-06-01 | 2012-01-18 |
| Initial Study of Rituximab to Treat Primary Biliary Cirrhosis rituximab - Primary Biliary Cirrhosis | Phase 1 / Phase 2 | Completed | University of California, Davis | 6 | 2007-01-01 | 2017-07-02 |
Liver Cirrhosis, Biliary (6) · Alagille Syndrome (2) · Cholestasis, progressive familial intrahepatic 1 (2) · Biliary Atresia (1) · Cholangitis, Sclerosing (1) · Cholestasis (1) · Fatigue (1) · Liver Cirrhosis (1)
Bile Duct Diseases (6) · Biliary Tract Diseases (6) · Cholestasis, Intrahepatic (6) · Digestive System Diseases (6) · Fibrosis (6) · Liver Diseases (6) · Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6) · Cholestasis (5) · Liver Cirrhosis (5) · Congenital Abnormalities (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Abnormalities, Multiple (2) · Cardiovascular Abnormalities (2) · Cardiovascular Diseases (2)
Cholestyramine Resin (1) · Indocyanine Green (1) · Modafinil (1) · Rituximab (1) · Transplantation (1) · cholylsarcosine (1)
Albireo (2) · Mayo Clinic (1) · University of Aarhus (1) · University of California, Davis (1) · Vinmec Research Institute of Stem Cell and Gene Technology (1)
United States (2) · Denmark (1) · United Kingdom (1) · Vietnam (1)
Christopher L Bowlus, MD (1) · Keith D Lindor, M.D. (1) · Liem Nguyen (1) · M. Eric Gershwin, MD (1) · Susanne Keiding, M.D. D.Sc. (1)
PMID 27148676, PMID 28249726, PMID 40907882
2016 (1)